| Aug 27, 2026 (view filing)4:10 PM ET | Aug 25 | 2 days | Morrison Jodie PopeCEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.85K | $16.56 | −$163.0K | −2.8%343.3K after | |
| Aug 27, 2026 (view filing)4:10 PM ET | Aug 25 | 2 days | Kalowski LeeCFO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.97K | $16.56 | −$65.8K | −2.8%138.5K after | |
| Aug 27, 2026 (view filing)4:10 PM ET | Aug 25 | 2 days | Violette Shelia M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.80K | $16.56 | −$46.3K | −2.1%127.8K after | |
| Jun 1, 2026 (view filing)9:13 PM ET | May 28 | 4 days | OrbiMed Advisors LLC and 2 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.88M | $8.00 | +$15.0M | New position625.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Jun 1, 2026 (view filing) | May 28 | 4 days | Xu DiyongDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.88M | $8.00 | +$15.0M | New position625.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 27, 2026 (view filing) | Feb 25 | 2 days | Kalowski LeeCFO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.00K | $4.51 | −$18.0K | −10.0%35.9K after | |
| Feb 27, 2026 (view filing) | Feb 25 | 2 days | Morrison Jodie PopeCEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.90K | $4.51 | −$44.6K | −10.0%89.1K after | |
| Feb 27, 2026 (view filing) | Feb 25 | 2 days | Violette Shelia M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.81K | $4.51 | −$12.7K | −4.8%55.6K after | |
| Dec 4, 2025 (view filing) | Dec 2 | 2 days | Morrison Jodie PopeCEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.5K | $3.46 | −$77.9K | −18.5%99.0K after | |
| Dec 4, 2025 (view filing) | Dec 2 | 2 days | Kalowski LeeCFO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.07K | $3.46 | −$31.4K | −18.5%39.9K after | |
| Aug 28, 2025 (view filing) | Aug 26 | 2 days | Morrison Jodie PopeCEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.5K | $1.80 | −$18.9K | −8.0%121.5K after | |
| Aug 28, 2025 (view filing) | Aug 26 | 2 days | Violette Shelia M.Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.99K | $1.80 | −$5.38K | −4.9%58.4K after | |
| Aug 28, 2025 (view filing) | Aug 26 | 2 days | Kalowski LeeCFO and President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.24K | $1.80 | −$7.63K | −8.0%49.0K after | |
| Aug 14, 2024 (view filing) | Mar 25 | 142 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Tzianabos ArthurDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −265 | $24.20 | −$6.41K | −3.2%7.98K after | |
| Apr 23, 2024 (view filing) | Mar 25 | 29 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Alloway PaulSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −268 | $24.21 | −$6.49K | −9.4%2.60K after | |
| Apr 23, 2024 (view filing) | Mar 25 | 29 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Michaud Charles JrSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −75 | $24.20 | −$1.81K | −7.5%927 after | |
| Feb 15, 2024 (view filing) | Jan 9 | 37 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Tzianabos ArthurDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.0K | $0.57 | −$7.43K | −9.2%128.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 5, 2024 (view filing) | Jan 3 | 2 days | Alloway PaulSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.28K | $0.57 | −$4.15K | −20.6%28.0K after | |
| Jan 5, 2024 (view filing) | Jan 3 | 2 days | Michaud Charles JrSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.71K | $0.57 | −$973.56 | −12.8%11.6K after | |
| Sep 8, 2023 (view filing) | Sep 6 | 2 days | Seymour AlbertSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.45K | $1.15 | −$1.67K | −1.0%150.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 7, 2023 (view filing) | Aug 3 | 4 days | Jordan JulieChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.85K | $1.39 | −$2.58K | −19.8%7.50K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 4, 2023 (view filing) | Aug 2 | 2 days | Jordan JulieChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −99 | $1.31 | −$129.69 | −3.5%2.77K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 6, 2023 (view filing) | Mar 2 | 4 days | Alloway PaulSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.0K | $1.45 | −$15.9K | −39.6%16.7K after | |
| Jan 11, 2023 (view filing) | Jan 9 | 2 days | Blum Michael LeeChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.45K | $1.39 | −$3.41K | −15.3%13.5K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jan 11, 2023 (view filing) | Jan 9 | 2 days | Alloway PaulSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.09K | $1.39 | −$4.30K | −13.3%20.1K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jan 11, 2023 (view filing) | Jan 9 | 2 days | Seymour AlbertSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.62K | $1.39 | −$5.03K | −2.5%143.2K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
| Jan 11, 2023 (view filing) | Jan 9 | 2 days | Smith W BradfordSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.73K | $1.39 | −$5.18K | −20.8%14.2K after | |
| Jan 11, 2023 (view filing) | Jan 9 | 2 days | Tzianabos ArthurDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.6K | $1.39 | −$14.8K | −8.9%108.4K after | |
| Jan 12, 2022 (view filing) | Jan 5 | 7 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Smith W BradfordCFO & Treasurer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.18K | $3.78 | −$8.25K | −33.1%4.42K after | |
| Jan 12, 2022 (view filing) | Jan 5 | 7 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Kelly Timothy PChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.41K | $3.78 | −$5.31K | −38.7%2.22K after | |
| Jan 12, 2022 (view filing) | Jan 5 | 7 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Seymour AlbertChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.66K | $3.78 | −$6.28K | −1.2%131.6K after | |
| Jan 12, 2022 (view filing) | Jan 5 | 7 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Cohn GabrielChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.66K | $3.78 | −$6.28K | −38.7%2.63K after | |
| Jan 12, 2022 (view filing) | Jan 5 | 7 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Tzianabos ArthurPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.35K | $3.78 | −$20.2K | −5.9%86.0K after | |
| Sep 8, 2021 (view filing) | Sep 3 | 5 days | Kelly Timothy PSee Remarks. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −54 | $7.70 | −$415.8 | −100.0%0 after | |
| Sep 8, 2021 (view filing) | Mar 1 | 191 days | Kelly Timothy PSee Remarks | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.23K | $11.16 | −$69.5K | −100.0%0 after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. |
