| Aug 14, 2026 (view filing)4:52 PM ET | Aug 12 | 2 days | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.0K | $43.68 | −$785.0K | −25.5%52.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 2, 2026 (view filing)5:21 PM ET | Jul 1 | 1 day | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −200.0K | $39.41 | −$7.88M | −89.1%24.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 5, 2026 (view filing) | May 4-5 | 1 day | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −55.2K | $37.88 | −$2.09M | −92.7%4.37K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 2, 2026 (view filing) | Apr 1 | 1 day | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.7K | $32.31 | −$926.1K | −74.9%9.60K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 31, 2026 (view filing) | Mar 31 | Same day | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −21.3K | $32.12 | −$685.4K | −69.0%9.60K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 30, 2026 (view filing) | Mar 27 | 3 days | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.4K | $30.98 | −$506.8K | −63.0%9.60K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 23, 2026 (view filing)1:34 PM ET | Jan 21 | 2 days | Edris BadreddinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −115.5K | $29.44 | −$3.40M | −85.4%19.8K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2025 (view filing)6:06 PM ET | Nov 12 | 1 day | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $21.12 | −$2.11M | −81.0%23.4K after | |
| Nov 13, 2025 (view filing) | Nov 11 | 2 days | Fox Jonathan CDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.7K | $18.64 | +$199.4K | +82.3%23.7K after | |
| Aug 28, 2025 (view filing)4:55 PM ET | Aug 26 | 2 days | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $14.60 | −$1.46M | −81.0%23.4K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.10K | $13.39 | −$28.1K | −17.0%10.2K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.49K | $13.39 | −$33.4K | −9.5%23.6K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Carruthers R MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.43K | $13.39 | −$19.1K | −1.6%86.2K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.91K | $13.39 | −$25.5K | −7.5%23.4K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.97K | $13.39 | −$106.7K | −20.7%30.6K after | |
| Aug 14, 2025 (view filing) | Aug 12 | 2 days | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.86K | $13.39 | −$38.3K | −10.1%25.4K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.55K | $16.45 | −$25.5K | −7.7%18.5K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.93K | $16.45 | −$31.7K | −22.8%6.53K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.28K | $16.45 | −$70.3K | −17.2%20.6K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.19K | $16.45 | −$85.3K | −19.4%21.6K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.69K | $16.45 | −$27.8K | −7.7%20.4K after | |
| May 7, 2025 (view filing) | May 2 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Carruthers R MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.31K | $16.45 | −$21.6K | −1.6%81.0K after | |
| Apr 4, 2025 (view filing)7:33 PM ET | Apr 3 | 1 day | OrbiMed Advisors LLC and 2 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +496.8K | $20.13 | +$10.0M | New position443.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Apr 4, 2025 (view filing) | Apr 3 | 1 day | Thompson Peter A.Director, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +496.8K | $20.13 | +$10.0M | New position443.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 11, 2025 (view filing)4:33 PM ET | Mar 7 | 4 days | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −200 | $30.02 | −$6.00K | −1.3%14.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2025 (view filing)4:32 PM ET | Mar 7 | 4 days | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100 | $30.00 | −$3.00K | −0.7%14.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 7, 2025 (view filing)4:38 PM ET | Feb 5-6 | 2 days | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.21K | $30.04 | −$276.8K | −38.3%14.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 7, 2025 (view filing)4:38 PM ET | Feb 5-6 | 2 days | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.54K | $30.13 | −$287.3K | −39.7%14.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 7, 2025 (view filing) | Feb 5 | 2 days | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $30.03 | −$300.3K | −37.3%16.8K after | |
| Jan 30, 2025 (view filing) | Jan 28 | 2 days | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $27.63 | −$690.8K | −60.4%16.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 31, 2024 (view filing)5:13 PM ET | Dec 30 | 1 day | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100.0K | $27.37 | −$2.74M | −87.1%14.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 27, 2024 (view filing) | Dec 24 | 3 days | Semigran MarcChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.7K | $29.68 | −$881.9K | −81.6%6.72K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 24, 2024 (view filing)8:25 PM ET | Sep 20 | 4 days | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −75.0K | $28.27 | −$2.12M | −85.5%12.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 24, 2024 (view filing) | Sep 20-23 | 4 days | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −70.9K | $28.15 | −$2.00M | −95.6%3.25K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 24, 2024 (view filing) | Sep 20 | 4 days | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.16K | $28.29 | −$202.6K | −33.0%14.5K after | |
| Sep 24, 2024 (view filing) | Sep 20 | 4 days | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −42.1K | $29.03 | −$1.22M | −73.6%15.1K after | |
| Sep 24, 2024 (view filing) | Sep 20 | 4 days | Carruthers R MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −125.1K | $28.57 | −$3.57M | −94.8%6.90K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| May 3, 2024 (view filing) | May 2 | 1 day | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.96K | $18.91 | −$37.0K | −37.6%3.25K after | |
| May 3, 2024 (view filing) | May 2 | 1 day | Carruthers R MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.16K | $18.91 | −$40.8K | −5.8%35.2K after | |
| May 3, 2024 (view filing) | May 2 | 1 day | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.72K | $18.91 | −$32.5K | −11.3%13.4K after | |
| May 3, 2024 (view filing) | May 2 | 1 day | Russell Alan JChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.58K | $18.91 | −$29.8K | −17.9%7.24K after | |
| May 3, 2024 (view filing) | May 2 | 1 day | Donovan Joanne M.CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.68K | $18.91 | −$69.6K | −15.6%19.9K after | |
| May 3, 2024 (view filing) | May 2 | 1 day | Koch KevinPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.15K | $18.91 | −$59.6K | −17.9%14.5K after | |
| Feb 9, 2024 (view filing) | Feb 7-9 | 2 days | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.8K | $20.00 | −$596.8K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 9, 2024 (view filing) | Feb 7-9 | 2 days | Derakhshan BehradChief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $20.02 | −$200.2K | −58.8%7.02K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 25, 2024 (view filing)4:28 PM ET | Jan 23 | 2 days | OrbiMed Advisors LLC and 2 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +454.5K | $11.00 | +$5.00M | +3.3%14.4M after | Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Jan 25, 2024 (view filing) | Jan 23 | 2 days | Carruthers R MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −90.0K | $15.78 | −$1.42M | −75.6%29.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 25, 2024 (view filing) | Jan 23 | 2 days | Thompson Peter A.Director, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +454.5K | $11.00 | +$5.00M | +3.3%14.4M after | |
| Dec 28, 2023 (view filing) | Dec 26 | 2 days | Fox Jonathan CDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.9K | $9.30 | +$101.0K | New position10.9K after | |
| Dec 28, 2023 (view filing) | Dec 27 | 1 day | Moore John RGeneral Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.50K | $10.50 | −$89.2K | −100.0%0 after | |
