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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Edgewise Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
226
+15 vs. Q1 2026
Shares held
119.2M
+6.30M (+5.6%) vs. Q1 2026
Total value
$4.82B
+$1.28B (+36.1%) vs. Q1 2026
New holders
42
83 more added
Sold out
27
73 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 226 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ2 2026: $4.82B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $648.7MQ4 2022: $594.1MQ1 2023: $496.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $874.3MQ1 2024: $1.69BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.33BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.73BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.73B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.33B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.69B
Q4 2023116$874.3M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$496.1M
Q4 202290$594.1M
Q3 202294$648.7M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding EWTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC15,518,492$630.5M11.94%00.0%Unchanged
Paradigm Biocapital Advisors LP10,215,455$415.1M7.77%+2,850,417+38.7%Added
Ra Capital Management, L.P.8,392,730$341.0M2.96%−2,035,707−19.5%Reduced
BlackRock, Inc.6,606,336$268.4M0.00%+133,345+2.1%Added
Jupiter Topco LLC6,075,331$246.9M0.10%+6,075,331New
FMR LLC5,489,135$223.0M0.01%+4,472,083+439.7%Added
Novo Holdings A/S5,350,000$217.4M12.62%00.0%Unchanged
Driehaus Capital Management LLC4,728,623$192.1M1.11%+250,681+5.6%Added
Perceptive Advisors LLC4,373,974$177.7M2.76%−50,000−1.1%Reduced
Vanguard Capital Management LLC3,860,670$156.9M0.00%+72,509+1.9%Added
Baker Bros. Advisors LP3,701,719$150.4M0.75%−2,874,221−43.7%Reduced
Siren, L.L.C.3,184,629$129.4M2.63%−1,245,634−28.1%Reduced
Cormorant Asset Management, LP2,510,000$102.0M5.23%−750,000−23.0%Reduced
Geode Capital Management, LLC2,174,051$88.3M0.00%+384,232+21.5%Added
Integral Health Asset Management, LLC2,000,000$81.3M3.33%+400,000+25.0%Added
Braidwell LP1,996,965$81.1M3.00%−350,618−14.9%Reduced
Morgan Stanley1,948,597$79.2M0.00%−297,431−13.2%Reduced
State Street Corp1,827,927$74.3M0.00%+111,104+6.5%Added
Alliancebernstein L.P.2,119,024$66.7M0.02%+396,855+23.0%Added
MPM Oncology Impact Management LP1,620,780$65.9M4.02%−39,916−2.4%Reduced
Bank of America Corp1,558,260$63.3M0.00%+230,900+17.4%Added
Qube Research & Technologies Ltd1,252,507$50.9M0.06%+426,597+51.7%Added
Dimensional Fund Advisors LP1,139,726$46.3M0.01%−79,991−6.6%Reduced
American Century Companies Inc1,127,078$45.8M0.02%−20,098−1.8%Reduced
First Light Asset Management, LLC1,095,171$44.5M2.70%+93,325+9.3%Added
Victory Capital Management Inc902,870$36.7M0.02%+113,827+14.4%Added
Price T Rowe Associates Inc816,518$33.2M0.00%+747,091+1,076.1%Added
Vanguard Portfolio Management LLC786,456$32.0M0.00%+229,196+41.1%Added
Northern Trust Corp671,270$27.3M0.00%+94,714+16.4%Added
Standard Life Aberdeen plc647,926$26.3M0.04%−178,133−21.6%Reduced
Charles Schwab Investment Management Inc620,532$25.2M0.00%+24,222+4.1%Added
Tyro Capital Management LLC612,965$24.9M5.59%+612,965New
Goldman Sachs Group Inc599,469$24.4M0.00%−30,351−4.8%Reduced
Parkman Healthcare Partners LLC577,036$23.4M2.41%+254,208+78.7%Added
Artisan Partners Limited Partnership574,925$23.4M0.04%−84,142−12.8%Reduced
Vanguard Fiduciary Trust Co548,285$22.3M0.00%+26,559+5.1%Added
Norges Bank510,140$20.7M0.00%+510,140New
Opaleye Management Inc.500,000$20.3M1.84%00.0%Unchanged
Citadel Advisors LLC469,707$19.1M0.01%+40,675+9.5%Added
Adage Capital Partners GP, L.L.C.462,000$18.8M0.03%+462,000New
Soleus Capital Management, L.P.450,889$18.3M0.63%−999,026−68.9%Reduced
Nuveen, LLC414,706$16.8M0.00%+78,923+23.5%Added
Sofinnova Investments, Inc.380,923$15.5M0.83%−5,575−1.4%Reduced
Healthcare of Ontario Pension Plan Trust Fund334,014$13.6M0.02%−70,186−17.4%Reduced
Raymond James Financial Inc317,565$12.9M0.00%+297,887+1,513.8%Added
Squadron Capital Management LLC290,000$11.8M4.03%−60,000−17.1%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH283,333$11.5M0.02%+210.0%Added
Diadema Partners LP272,214$11.1M3.91%+272,214New
Prudential Financial Inc260,725$10.6M0.01%+250,120+2,358.5%Added
Kennedy Capital Management, Inc.256,608$10.4M0.18%−7,596−2.9%Reduced
Schonfeld Strategic Advisors LLC255,202$10.4M0.05%+156,127+157.6%Added
Deutsche Bank AG244,995$9.95M0.00%+23,127+10.4%Added
DAFNA Capital Management LLC226,819$9.22M1.76%+114,583+102.1%Added
Woodline Partners LP224,290$9.11M0.03%00.0%Unchanged
Bank of New York Mellon Corp212,347$8.63M0.00%+19,913+10.3%Added
JPMorgan Chase & Co203,151$8.48M0.00%+55,578+37.7%Added
Peregrine Capital Management LLC198,570$8.07M0.26%−10,102−4.8%Reduced
SEB Asset Management AB194,063$7.88M0.03%−12,449−6.0%Reduced
Granahan Investment Management Inc193,778$7.87M0.28%−7,065−3.5%Reduced
Neuberger Berman Group LLC191,195$7.77M0.01%+22,517+13.3%Added
Barclays PLC190,205$7.73M0.00%+12,961+7.3%Added
D. E. Shaw & Co., Inc.189,115$7.68M0.00%+84,252+80.3%Added
UBS Group AG174,967$7.11M0.00%−1,136,158−86.7%Reduced
ADAR1 Capital Management, LLC143,199$5.82M0.27%+52,600+58.1%Added
KVP Capital Advisors, LP133,000$5.40M3.97%00.0%Unchanged
Invesco Ltd.120,932$4.91M0.00%−17,467−12.6%Reduced
UBS Asset Management Americas Inc118,209$4.80M0.00%+3,489+3.0%Added
Point72 Asset Management, L.P.117,262$4.76M0.01%+117,262New
Quantum Private Wealth, LLC113,380$4.61M1.18%−3,244−2.8%Reduced
Alps Advisors Inc108,795$4.42M0.02%+21,469+24.6%Added
Moody Aldrich Partners LLC104,952$4.26M0.77%−9,189−8.1%Reduced
Artia Global Partners LP98,800$4.01M0.76%+33,300+50.8%Added
Swiss National Bank96,800$3.93M0.00%−7,100−6.8%Reduced
Voya Investment Management LLC94,671$3.85M0.00%+55,518+141.8%Added
HSBC Holdings PLC91,638$3.72M0.00%+91,638New
HighVista Strategies LLC90,996$3.70M0.84%−935−1.0%Reduced
Rhumbline Advisers90,232$3.67M0.00%+6,692+8.0%Added
Ally Bridge Group (NY) LLC83,300$3.38M4.36%−77,700−48.3%Reduced
Boothbay Fund Management, LLC82,734$3.36M0.06%+82,734New
New York State Common Retirement Fund80,197$3.26M0.00%−8,740−9.8%Reduced
Wells Fargo & Company78,898$3.21M0.00%+53,654+212.5%Added
Russell Investments Group, Ltd.77,733$3.16M0.00%+71,159+1,082.4%Added
Jefferies Financial Group Inc.71,389$2.90M0.03%+71,389New
California State Teachers Retirement System71,306$2.90M0.00%−2,113−2.9%Reduced
Persistent Asset Partners Ltd69,441$2.82M0.89%+59,388+590.7%Added
Nomura Asset Management International Inc.64,918$2.64M0.00%−2,490−3.7%Reduced
DekaBank Deutsche Girozentrale80,000$2.52M0.00%00.0%Unchanged
Citigroup Inc59,563$2.42M0.00%+41,046+221.7%Added
Tudor Investment Corp Et Al56,934$2.31M0.01%+27,045+90.5%Added
State of Wisconsin Investment Board56,910$2.31M0.00%+24,014+73.0%Added
HighMark Wealth Management LLC53,179$2.16M0.72%00.0%Unchanged
Two Sigma Investments, LP49,548$2.01M0.00%−1,300−2.6%Reduced
SEI Investments Co47,543$1.93M0.00%−1,539−3.1%Reduced
Algert Global LLC47,240$1.92M0.02%+14,720+45.3%Added
XTX Topco Ltd45,832$1.86M0.02%+26,724+139.9%Added
Legal & General Group Plc44,688$1.82M0.00%+2,151+5.1%Added
Gsa Capital Partners LLP44,466$1.81M0.11%+44,466New
BNP Paribas Arbitrage, SA43,587$1.77M0.00%+19,676+82.3%Added
MetLife Investment Management41,804$1.70M0.01%+3,720+9.8%Added
Manufacturers Life Insurance Company, The40,757$1.66M0.00%+5,307+15.0%Added