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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
85
−5 vs. Q4 2022
Shares held
66.5M
+2.17K (0.0%) vs. Q4 2022
Total value
$443.1M
−$151.0M (−25.4%) vs. Q4 2022
New holders
9
30 more added
Sold out
14
25 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 85 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2023: $443.1M
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2022.

Institutions holding EWTX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC14,567,176$97.2M1.92%00.0%Unchanged
FMR LLC7,940,542$53.0M0.00%−648,687−7.6%Reduced
Novo Holdings A/S6,071,703$40.5M2.89%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors4,909,146$32.7M0.15%+500,000+11.3%Added
Deerfield Management Company, L.P. (Series C)3,933,137$26.2M0.58%00.0%Unchanged
EcoR1 Capital, LLC3,493,194$23.3M0.75%00.0%Unchanged
Deep Track Capital, LP3,068,259$20.5M0.87%−306,135−9.1%Reduced
Cormorant Asset Management, LP2,946,887$19.7M1.29%00.0%Unchanged
BlackRock Inc.2,871,007$19.1M0.00%−2,617−0.1%Reduced
Citadel Advisors LLC2,768,438$18.5M0.02%−78,081−2.7%Reduced
Vanguard Group Inc2,005,825$13.4M0.00%+22,821+1.2%Added
New Leaf Venture Partners, L.L.C.1,553,661$10.4M8.56%00.0%Unchanged
Geode Capital Management, LLC775,487$5.17M0.00%+53,342+7.4%Added
Janus Henderson Group PLC769,799$5.13M0.00%−650,070−45.8%Reduced
Goldman Sachs Group Inc754,139$5.03M0.00%−310,982−29.2%Reduced
Opaleye Management Inc.750,000$5.00M1.50%+138,600+22.7%Added
Granahan Investment Management Inc733,664$4.89M0.15%+733,664New
DAFNA Capital Management LLC733,239$4.89M1.47%−33,604−4.4%Reduced
Frazier Life Sciences Management, L.P.682,461$4.55M0.33%+682,461New
State Street Corp658,623$4.39M0.00%+59,103+9.9%Added
American Century Companies Inc509,062$3.39M0.00%+3,379+0.7%Added
Baker Bros. Advisors LP500,000$3.33M0.02%00.0%Unchanged
Woodline Partners LP360,093$2.40M0.03%+20.0%Added
Wellington Management Group LLP340,906$2.27M0.00%00.0%Unchanged
Northern Trust Corp306,084$2.04M0.00%−10,748−3.4%Reduced
Charles Schwab Investment Management Inc294,311$1.96M0.00%−2,564−0.9%Reduced
Candriam Luxembourg S.C.A.298,000$1.83M0.01%00.0%Unchanged
Tekla Capital Management LLC195,025$1.30M0.05%00.0%Unchanged
ExodusPoint Capital Management, LP141,851$946.0K0.01%+23,901+20.3%Added
UBS Oconnor LLC132,968$886.9K0.02%+132,968New
Bank of New York Mellon Corp123,880$826.3K0.00%−3,815−3.0%Reduced
Price T Rowe Associates Inc122,570$819.0K0.00%−135,756−52.6%Reduced
Nuveen Asset Management, LLC97,824$653.0K0.00%−8,878−8.3%Reduced
Renaissance Technologies LLC96,800$646.0K0.00%+19,200+24.7%Added
Morgan Stanley64,273$428.7K0.00%+3,972+6.6%Added
Parkman Healthcare Partners LLC62,283$415.4K0.09%+9,387+17.7%Added
Rhumbline Advisers58,331$389.0K0.00%+7,341+14.4%Added
Martingale Asset Management L P56,763$378.6K0.01%+27,900+96.7%Added
Bank of America Corp54,573$364.0K0.00%+1,993+3.8%Added
Quantum Private Wealth, LLC48,719$325.0K0.18%+11,461+30.8%Added
Alps Advisors Inc41,679$278.0K0.00%−1,227−2.9%Reduced
Cornercap Investment Counsel Inc31,904$212.8K0.04%+31,904New
Jane Street Group, LLC31,653$211.1K0.00%−224−0.7%Reduced
JPMorgan Chase & Co31,380$210.0K0.00%+7,063+29.0%Added
DekaBank Deutsche Girozentrale30,000$200.0K0.00%00.0%Unchanged
Barclays PLC28,016$186.9K0.00%+9,783+53.7%Added
Dimensional Fund Advisors LP27,283$182.0K0.00%+1,091+4.2%Added
Alliancebernstein L.P.25,800$172.1K0.00%+2,900+12.7%Added
D. E. Shaw & Co., Inc.24,736$165.0K0.00%+13,462+119.4%Added
Deutsche Bank AG23,597$157.4K0.00%+6,960+41.8%Added
MetLife Investment Management23,355$155.8K0.00%00.0%Unchanged
PDT Partners, LLC19,343$129.0K0.02%+108+0.6%Added
American International Group, Inc.18,294$122.0K0.00%+364+2.0%Added
Susquehanna International Group, LLP16,885$112.6K0.00%+16,885New
State Board of Administration of Florida Retirement System16,650$111.1K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)16,400$109.0K0.00%+9,796+148.3%Added
Mirae Asset Global Investments Co., Ltd.16,117$107.5K0.00%−40−0.2%Reduced
Balyasny Asset Management LLC15,240$101.7K0.00%−3,100−16.9%Reduced
SG Americas Securities, LLC15,080$101.0K0.00%+1,447+10.6%Added
Manufacturers Life Insurance Company, The14,434$96.3K0.00%00.0%Unchanged
California State Teachers Retirement System14,092$94.0K0.00%−1,040−6.9%Reduced
Voya Investment Management LLC13,608$90.8K0.00%00.0%Unchanged
New York State Common Retirement Fund13,384$89.3K0.00%−10,731−44.5%Reduced
Virtus ETF Advisers LLC12,507$83.4K0.05%−4,807−27.8%Reduced
Schonfeld Strategic Advisors LLC12,218$81.5K0.00%+12,218New
Principal Financial Group Inc12,178$81.2K0.00%+1,230+11.2%Added
Invesco Ltd.11,863$79.1K0.00%−1,004−7.8%Reduced
SFMG, LLC10,000$66.7K0.01%00.0%Unchanged
Federated Hermes, Inc.9,103$60.7K0.00%+1,392+18.1%Added
Wells Fargo & Company6,757$45.1K0.00%+6,757New
Amalgamated Bank3,943$26.0K0.00%−993−20.1%Reduced
Legal & General Group Plc3,634$24.2K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,990$19.9K0.00%00.0%Unchanged
Royal Bank of Canada2,825$19.0K0.00%−1,547−35.4%Reduced
Simplex Trading, LLC2,975$19.0K0.00%+2,975New
Metropolitan Life Insurance Co2,092$14.0K0.00%−712−25.4%Reduced
China Universal Asset Management Co., Ltd.857$5.72K0.00%+215+33.5%Added
Citigroup Inc719$4.80K0.00%−204−22.1%Reduced
Lindbrook Capital, LLC523$3.49K0.00%+362+224.8%Added
Daiwa Securities Group Inc.254$2.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.202$1.35K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.169$1.13K0.00%+81+92.0%Added
Signaturefd, LLC123$8200.00%−163−57.0%Reduced
Massmutual Trust Co FSB102$6800.00%00.0%Unchanged
Parallel Advisors, LLC77$5140.00%+77New
HighVista Strategies LLC0$00.00%−187,480−100.0%Sold out
Millennium Management LLC0$00.00%−42,208−100.0%Sold out
Trexquant Investment LP0$00.00%−32,014−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−26,367−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−18,105−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−11,294−100.0%Sold out
ProShare Advisors LLC0$00.00%−10,105−100.0%Sold out
Sandia Investment Management LP0$00.00%−5,000−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−2,900−100.0%Sold out
UBS Group AG0$00.00%−1,551−100.0%Sold out
Quantbot Technologies LP0$00.00%−1,300−100.0%Sold out
US Bancorp0$00.00%−236−100.0%Sold out
Ellevest, Inc.0$00.00%−108−100.0%Sold out
Credit Suisse AG0$00.00%−1−100.0%Sold out