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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Edgewise Therapeutics, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+31 vs. Q3 2023
Shares held
79.6M
+11.2M (+16.4%) vs. Q3 2023
Total value
$871.4M
+$479.2M (+122.2%) vs. Q3 2023
New holders
38
43 more added
Sold out
7
20 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 116 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ4 2023: $871.4M
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q3 2023.

Institutions holding EWTX in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC14,567,176$159.4M3.19%00.0%Unchanged
FMR LLC6,492,513$71.0M0.01%+89,666+1.4%Added
Viking Global Investors LPSuperinvestorViking Global Investors6,159,146$67.4M0.25%00.0%Unchanged
Novo Holdings A/S6,071,703$66.4M4.44%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)3,933,137$43.0M0.79%00.0%Unchanged
EcoR1 Capital, LLC3,493,194$38.2M0.99%00.0%Unchanged
BlackRock Inc.3,307,110$36.2M0.00%+321,266+10.8%Added
Baker Bros. Advisors LP3,112,786$34.1M0.39%+2,063,087+196.5%Added
Frazier Life Sciences Management, L.P.2,667,203$29.2M1.56%+1,818,181+214.2%Added
Citadel Advisors LLC2,585,930$28.3M0.03%−181,506−6.6%Reduced
Cormorant Asset Management, LP2,551,989$27.9M1.34%−394,898−13.4%Reduced
Deep Track Capital, LP2,537,176$27.8M0.97%−212,824−7.7%Reduced
Vanguard Group Inc2,125,380$23.3M0.00%+60,959+3.0%Added
New Leaf Venture Partners, L.L.C.1,553,661$17.0M13.69%00.0%Unchanged
Janus Henderson Group PLC1,215,013$13.2M0.01%+94,246+8.4%Added
Hudson Bay Capital Management LP1,187,880$13.0M0.11%+1,187,880New
Granahan Investment Management Inc1,074,908$11.8M0.39%+135,781+14.5%Added
Logos Global Management LP950,000$10.4M1.16%+950,000New
Geode Capital Management, LLC947,046$10.4M0.00%+55,278+6.2%Added
State Street Corp892,709$9.77M0.00%+104,449+13.3%Added
Goldman Sachs Group Inc881,896$9.65M0.00%−65,898−7.0%Reduced
Barclays PLC778,916$8.52M0.00%+760,637+4,161.3%Added
American Century Companies Inc770,452$8.43M0.01%+242,613+46.0%Added
Opaleye Management Inc.699,000$7.65M2.05%−176,405−20.2%Reduced
Parkman Healthcare Partners LLC651,625$7.13M1.01%+178,313+37.7%Added
Perceptive Advisors LLC555,555$6.08M0.14%+555,555New
Point72 Asset Management, L.P.501,256$5.48M0.02%+501,256New
DAFNA Capital Management LLC449,384$4.92M1.18%−70,000−13.5%Reduced
Woodline Partners LP404,212$4.42M0.05%+44,119+12.3%Added
Driehaus Capital Management LLC395,069$4.32M0.05%+395,069New
Northern Trust Corp363,243$3.97M0.00%+18,327+5.3%Added
Kennedy Capital Management, Inc.342,864$3.75M0.08%+342,864New
Wellington Management Group LLP340,906$3.73M0.00%00.0%Unchanged
Charles Schwab Investment Management Inc331,059$3.62M0.00%+200+0.1%Added
Sectoral Asset Management Inc327,801$3.59M1.54%+327,801New
Vontobel Holding Ltd.327,801$3.59M0.03%+327,801New
Schonfeld Strategic Advisors LLC319,100$3.49M0.03%+202,200+173.0%Added
Candriam Luxembourg S.C.A.308,000$3.37M0.02%+10,000+3.4%Added
Ikarian Capital, LLC270,000$2.95M0.81%+270,000New
Dimensional Fund Advisors LP262,238$2.87M0.00%+87,317+49.9%Added
Morgan Stanley225,179$2.46M0.00%+152,108+208.2%Added
Two Sigma Investments, LP169,542$1.85M0.00%+111,978+194.5%Added
Nuveen Asset Management, LLC153,292$1.68M0.00%+806+0.5%Added
Standard Life Aberdeen plc150,418$1.65M0.00%+150,418New
Bank of New York Mellon Corp146,170$1.60M0.00%−114−0.1%Reduced
Millennium Management LLC131,355$1.44M0.00%+95,462+266.0%Added
Price T Rowe Associates Inc126,071$1.38M0.00%+367+0.3%Added
UBS Oconnor LLC114,685$1.25M0.04%−25,173−18.0%Reduced
Pale Fire Capital SE98,449$1.08M0.17%+82,804+529.3%Added
DekaBank Deutsche Girozentrale80,000$920.0K0.00%00.0%Unchanged
Boothbay Fund Management, LLC72,117$789.0K0.03%+72,117New
New York State Common Retirement Fund70,693$773.4K0.00%+26,822+61.1%Added
Renaissance Technologies LLC64,700$708.0K0.00%−86,300−57.2%Reduced
Rhumbline Advisers64,333$703.8K0.00%+723+1.1%Added
Quantum Private Wealth, LLC63,219$691.6K0.29%+1,500+2.4%Added
Bank of America Corp62,268$681.2K0.00%+21,042+51.0%Added
Martingale Asset Management L P61,384$671.5K0.01%−100.0%Reduced
Trexquant Investment LP55,591$608.2K0.01%+55,591New
Susquehanna International Group, LLP54,436$595.5K0.00%+54,436New
Gsa Capital Partners LLP52,660$576.0K0.05%+8,696+19.8%Added
Swiss National Bank50,100$548.1K0.00%+50,100New
Jump Financial, LLC47,100$515.3K0.02%+47,100New
Jane Street Group, LLC44,139$482.9K0.00%+44,139New
Alps Advisors Inc43,226$472.9K0.00%−3,648−7.8%Reduced
Two Sigma Advisers, LP40,900$447.4K0.00%+30,700+301.0%Added
JPMorgan Chase & Co40,063$438.3K0.00%−441−1.1%Reduced
HRT Financial LP38,788$424.0K0.00%+38,788New
Alliancebernstein L.P.37,420$409.4K0.00%+2,320+6.6%Added
Checkpoint Capital L.P.33,000$361.0K0.25%+33,000New
D. E. Shaw & Co., Inc.31,950$349.5K0.00%+31,950New
SG Americas Securities, LLC29,826$326.0K0.00%+11,128+59.5%Added
California State Teachers Retirement System29,620$324.0K0.00%+20,179+213.7%Added
PDT Partners, LLC29,259$320.1K0.04%+29,259New
Virtu Financial LLC24,037$263.0K0.02%+24,037New
UBS Asset Management Americas Inc23,613$258.3K0.00%+23,613New
MetLife Investment Management23,355$255.5K0.00%00.0%Unchanged
American International Group, Inc.21,267$232.7K0.00%−86−0.4%Reduced
Mirae Asset Global Investments Co., Ltd.20,833$227.9K0.00%+4,785+29.8%Added
Deutsche Bank AG20,410$223.3K0.00%−687−3.3%Reduced
Corton Capital Inc.20,218$221.2K0.07%+3,174+18.6%Added
Tower Research Capital LLC (TRC)18,237$199.5K0.00%+12,181+201.1%Added
Voya Investment Management LLC18,185$198.9K0.00%00.0%Unchanged
Credit Suisse AG17,299$189.3K0.00%+17,299New
Manufacturers Life Insurance Company, The17,258$188.8K0.00%−662−3.7%Reduced
XTX Topco Ltd17,143$187.5K0.04%+5,191+43.4%Added
State Board of Administration of Florida Retirement System16,870$184.6K0.00%00.0%Unchanged
Legal & General Group Plc16,657$182.2K0.00%+13,127+371.9%Added
Invesco Ltd.16,528$180.8K0.00%−6,447−28.1%Reduced
Principal Financial Group Inc16,400$179.4K0.00%−1,161−6.6%Reduced
Royal Bank of Canada14,084$154.0K0.00%+6,182+78.2%Added
EntryPoint Capital, LLC13,720$150.1K0.14%+13,720New
Wells Fargo & Company13,176$144.1K0.00%+2,602+24.6%Added
Squarepoint Ops LLC11,610$127.0K0.00%+11,610New
ProShare Advisors LLC11,137$121.8K0.00%+11,137New
SFMG, LLC10,000$109.4K0.01%00.0%Unchanged
AJOVista, LLC7,700$84.2K0.11%+7,700New
Natixis7,500$82.7K0.00%+7,500New
China Universal Asset Management Co., Ltd.7,338$80.3K0.02%+5,704+349.1%Added
Citigroup Inc7,261$79.4K0.00%+6,083+516.4%Added
Ameritas Investment Partners, Inc.4,190$45.8K0.00%00.0%Unchanged