Edgewise Therapeutics, Inc.
EWTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001710072
In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Edgewise Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 179
- −11 vs. Q1 2025
- Shares held
- 118.7M
- +13.4M (+12.8%) vs. Q1 2025
- Total value
- $1.56B
- −$763.4M (−32.9%) vs. Q1 2025
- New holders
- 30
- 88 more added
- Sold out
- 41
- 39 more reduced
3 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 226 | $4.82B |
| Q1 2026 | 214 | $3.72B |
| Q4 2025 | 199 | $3.02B |
| Q3 2025 | 173 | $1.82B |
| Q2 2025 | 179 | $1.56B |
| Q1 2025 | 193 | $2.32B |
| Q4 2024 | 201 | $2.64B |
| Q3 2024 | 177 | $2.71B |
| Q2 2024 | 140 | $1.83B |
| Q1 2024 | 129 | $1.67B |
| Q4 2023 | 116 | $871.4M |
| Q3 2023 | 85 | $392.2M |
| Q2 2023 | 95 | $538.8M |
| Q1 2023 | 85 | $443.1M |
| Q4 2022 | 90 | $594.1M |
| Q3 2022 | 94 | $633.5M |
| Q2 2022 | 78 | $405.7M |
| Q1 2022 | 72 | $523.5M |
| Q4 2021 | 58 | $769.4M |
| Q3 2021 | 48 | $795.8M |
| Q2 2021 | 46 | $1.03B |
| Q1 2021 | 31 | $1.48B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 15,518,492 | $203.4M | 5.12% | +496,771+3.3% | Added |
| Ra Capital Management, L.P. | 9,902,633 | $129.8M | 2.19% | +993,542+11.2% | Added |
| Baker Bros. Advisors LP | 7,305,940 | $95.8M | 0.93% | +1,150,000+18.7% | Added |
| BlackRock, Inc. | 6,781,046 | $88.9M | 0.00% | +296,038+4.6% | Added |
| Paradigm Biocapital Advisors LP | 6,142,344 | $80.5M | 3.44% | +1,747,788+39.8% | Added |
| Janus Henderson Group PLC | 5,503,349 | $72.1M | 0.04% | +221,195+4.2% | Added |
| Novo Holdings A/S | 5,350,000 | $70.1M | 4.95% | 00.0% | Unchanged |
| Braidwell LP | 5,210,831 | $68.3M | 2.34% | +2,752,023+111.9% | Added |
| Vanguard Group Inc | 4,841,500 | $63.5M | 0.00% | +547,096+12.7% | Added |
| Perceptive Advisors LLC | 4,639,949 | $60.8M | 2.28% | −1,907,379−29.1% | Reduced |
| Cormorant Asset Management, LP | 4,251,992 | $55.7M | 4.15% | +150,000+3.7% | Added |
| Siren, L.L.C. | 3,160,298 | $41.4M | 2.14% | +1,463,854+86.3% | Added |
| Bellevue Group AG | 2,775,997 | $36.4M | 0.80% | +1,347,068+94.3% | Added |
| Driehaus Capital Management LLC | 2,101,781 | $27.6M | 0.22% | +726,039+52.8% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,067,320 | $27.1M | 0.49% | −11,189−0.5% | Reduced |
| Geode Capital Management, LLC | 1,797,215 | $23.6M | 0.00% | +141,551+8.5% | Added |
| State Street Corp | 1,781,501 | $23.4M | 0.00% | +63,777+3.7% | Added |
| MPM Oncology Impact Management LP | 1,720,741 | $22.6M | 3.91% | +615,297+55.7% | Added |
| First Light Asset Management, LLC | 1,714,019 | $22.5M | 2.91% | −138,271−7.5% | Reduced |
| Artisan Partners Limited Partnership | 1,379,068 | $18.1M | 0.03% | +461,846+50.4% | Added |
| Woodline Partners LP | 1,096,863 | $14.4M | 0.08% | +540.0% | Added |
| Dimensional Fund Advisors LP | 1,048,936 | $13.8M | 0.00% | +381,437+57.1% | Added |
| New Leaf Venture Partners, L.L.C. | 1,030,161 | $13.5M | 40.97% | 00.0% | Unchanged |
| Integral Health Asset Management, LLC | 1,000,000 | $13.1M | 1.22% | +325,000+48.1% | Added |
| Polar Capital Holdings Plc | 975,000 | $12.8M | 0.07% | +725,000+290.0% | Added |
| Millennium Management LLC | 921,965 | $12.1M | 0.01% | +306,847+49.9% | Added |
| American Century Companies Inc | 783,166 | $10.3M | 0.01% | +3,400+0.4% | Added |
| Morgan Stanley | 727,714 | $9.54M | 0.00% | +318,717+77.9% | Added |
| Citigroup Inc | 724,899 | $9.50M | 0.01% | +650,592+875.5% | Added |
| Sofinnova Investments, Inc. | 716,873 | $9.40M | 0.64% | +374,655+109.5% | Added |
| Parkman Healthcare Partners LLC | 647,331 | $8.49M | 0.98% | +221,924+52.2% | Added |
| Goldman Sachs Group Inc | 631,743 | $8.28M | 0.00% | +265,099+72.3% | Added |
| Northern Trust Corp | 602,898 | $7.90M | 0.00% | −3,794−0.6% | Reduced |
| D. E. Shaw & Co., Inc. | 595,432 | $7.81M | 0.01% | +454,884+323.7% | Added |
| Foresite Capital Management VI LLC | 585,000 | $7.67M | 4.31% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 579,104 | $7.59M | 0.00% | +57,843+11.1% | Added |
| Eventide Asset Management, LLC | 568,310 | $7.45M | 0.13% | 00.0% | Unchanged |
| Sio Capital Management, LLC | 539,730 | $7.08M | 2.84% | +539,730 | New |
| Qube Research & Technologies Ltd | 499,917 | $6.55M | 0.01% | +102,344+25.7% | Added |
| Opaleye Management Inc. | 490,000 | $6.42M | 1.30% | +95,000+24.1% | Added |
| FMR LLC | 470,717 | $6.17M | 0.00% | +284,694+153.0% | Added |
| Standard Life Aberdeen plc | 443,319 | $5.81M | 0.01% | +130,294+41.6% | Added |
| Victory Capital Management Inc | 442,837 | $5.81M | 0.00% | +442,837 | New |
| Tang Capital Management LLC | 431,300 | $5.65M | 0.29% | +131,300+43.8% | Added |
| Granahan Investment Management Inc | 405,478 | $5.32M | 0.22% | +187,811+86.3% | Added |
| Eversept Partners, LP | 392,739 | $5.15M | 0.52% | +392,739 | New |
| Citadel Advisors LLC | 325,249 | $4.26M | 0.00% | +227,971+234.4% | Added |
| Nuveen, LLC | 317,173 | $4.16M | 0.00% | +114,593+56.6% | Added |
| Federated Hermes, Inc. | 316,500 | $4.15M | 0.01% | +316,420+395,525.0% | Added |
| Voloridge Investment Management, LLC | 284,551 | $3.73M | 0.01% | +284,551 | New |
| Barclays PLC | 281,250 | $3.69M | 0.00% | +172,688+159.1% | Added |
| Bank of America Corp | 254,429 | $3.34M | 0.00% | −440,997−63.4% | Reduced |
| Kynam Capital Management, LP | 253,979 | $3.33M | 0.36% | +253,979 | New |
| Kennedy Capital Management, Inc. | 252,524 | $3.31M | 0.08% | +27,824+12.4% | Added |
| DAFNA Capital Management LLC | 238,140 | $3.12M | 0.86% | +55,000+30.0% | Added |
| Candriam Luxembourg S.C.A. | 223,990 | $2.94M | 0.02% | −1,806−0.8% | Reduced |
| Bank of New York Mellon Corp | 212,858 | $2.79M | 0.00% | +2,123+1.0% | Added |
| UBS Asset Management Americas Inc | 191,606 | $2.51M | 0.00% | −81,251−29.8% | Reduced |
| UBS Group AG | 170,982 | $2.24M | 0.00% | −72,914−29.9% | Reduced |
| Schonfeld Strategic Advisors LLC | 167,340 | $2.19M | 0.02% | −111,633−40.0% | Reduced |
| Neuberger Berman Group LLC | 165,535 | $2.17M | 0.00% | +63,354+62.0% | Added |
| Schroder Investment Management Group | 151,062 | $1.98M | 0.00% | +71,911+90.9% | Added |
| Deutsche Bank AG | 147,525 | $1.93M | 0.00% | −228,535−60.8% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 132,178 | $1.73M | 0.00% | +42,753+47.8% | Added |
| Exome Asset Management LLC | 124,470 | $1.63M | 1.35% | +53,032+74.2% | Added |
| Jump Financial, LLC | 121,705 | $1.60M | 0.02% | +121,705 | New |
| DekaBank Deutsche Girozentrale | 80,000 | $1.56M | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 115,270 | $1.51M | 0.00% | −61,396−34.8% | Reduced |
| Campbell & CO Investment Adviser LLC | 114,181 | $1.50M | 0.09% | +114,181 | New |
| Wellington Management Group LLP | 112,570 | $1.48M | 0.00% | −733−0.6% | Reduced |
| Rhumbline Advisers | 112,483 | $1.47M | 0.00% | +3,646+3.3% | Added |
| Quantum Private Wealth, LLC | 100,774 | $1.32M | 0.43% | +10,050+11.1% | Added |
| Moody Aldrich Partners LLC | 99,848 | $1.31M | 0.25% | −82,247−45.2% | Reduced |
| New York State Common Retirement Fund | 93,808 | $1.23M | 0.00% | +22,358+31.3% | Added |
| Swiss National Bank | 90,000 | $1.18M | 0.00% | +7,400+9.0% | Added |
| Walleye Capital LLC | 86,882 | $1.14M | 0.01% | +70,704+437.0% | Added |
| Twinbeech Capital LP | 78,280 | $1.03M | 0.02% | −22,546−22.4% | Reduced |
| JPMorgan Chase & Co | 77,616 | $1.02M | 0.00% | −13,752−15.1% | Reduced |
| Alliancebernstein L.P. | 77,260 | $1.01M | 0.00% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 76,493 | $1.00M | 0.07% | +4,193+5.8% | Added |
| HighVista Strategies LLC | 69,723 | $914.1K | 0.34% | −21,484−23.6% | Reduced |
| XTX Topco Ltd | 60,739 | $796.3K | 0.03% | +60,739 | New |
| Alps Advisors Inc | 56,798 | $744.6K | 0.00% | −11,177−16.4% | Reduced |
| Invesco Ltd. | 56,158 | $736.2K | 0.00% | +8,028+16.7% | Added |
| UBS Oconnor LLC | 55,292 | $724.9K | 0.02% | +15,278+38.2% | Added |
| State of Wisconsin Investment Board | 54,019 | $708.2K | 0.00% | −17,113−24.1% | Reduced |
| Legal & General Group Plc | 52,307 | $685.7K | 0.00% | +1,959+3.9% | Added |
| HighMark Wealth Management LLC | 52,065 | $682.6K | 0.33% | +51,900+31,454.5% | Added |
| Price T Rowe Associates Inc | 50,682 | $665.0K | 0.00% | −244,199−82.8% | Reduced |
| Jane Street Group, LLC | 50,185 | $657.9K | 0.00% | +35,427+240.1% | Added |
| Norges Bank | 47,755 | $626.1K | 0.00% | 00.0% | Unchanged |
| Franklin Resources Inc | 45,806 | $600.5K | 0.00% | −481−1.0% | Reduced |
| ExodusPoint Capital Management, LP | 45,255 | $593.0K | 0.01% | +45,255 | New |
| Verition Fund Management LLC | 44,069 | $577.7K | 0.00% | +9,350+26.9% | Added |
| Intech Investment Management LLC | 44,065 | $577.7K | 0.01% | −2,143−4.6% | Reduced |
| MetLife Investment Management | 43,883 | $575.3K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 43,638 | $572.1K | 0.00% | +676+1.6% | Added |
| Tudor Investment Corp Et Al | 41,663 | $546.2K | 0.00% | −5,141−11.0% | Reduced |
| Quantbot Technologies LP | 41,463 | $543.6K | 0.01% | +41,463 | New |
| Graham Capital Management, L.P. | 40,364 | $529.2K | 0.02% | +23,317+136.8% | Added |