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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Edgewise Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
201
+25 vs. Q3 2024
Shares held
99.0M
−2.18M (−2.2%) vs. Q3 2024
Total value
$2.64B
−$58.2M (−2.2%) vs. Q3 2024
New holders
45
71 more added
Sold out
20
63 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 201 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ4 2024: $2.64B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding EWTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC15,021,721$401.1M8.33%00.0%Unchanged
Ra Capital Management, L.P.8,909,091$237.9M3.17%00.0%Unchanged
BlackRock, Inc.6,479,015$173.0M0.00%+85,448+1.3%Added
Baker Bros. Advisors LP6,155,940$164.4M1.76%+315,881+5.4%Added
Novo Holdings A/S5,000,000$133.5M8.08%−549,900−9.9%Reduced
Janus Henderson Group PLC4,983,940$133.0M0.07%+425,421+9.3%Added
Paradigm Biocapital Advisors LP4,493,929$120.0M4.17%+1,704,757+61.1%Added
Vanguard Group Inc4,466,849$119.3M0.00%−49,214−1.1%Reduced
Cormorant Asset Management, LP3,406,534$91.0M5.00%00.0%Unchanged
Perceptive Advisors LLC2,685,537$71.7M2.00%+355,243+15.2%Added
Braidwell LP2,332,196$62.3M1.85%+373,886+19.1%Added
Deerfield Management Company, L.P. (Series C)2,078,509$55.5M1.06%+297,503+16.7%Added
State Street Corp1,715,545$45.8M0.00%+30,430+1.8%Added
Geode Capital Management, LLC1,600,571$42.7M0.00%+1,036+0.1%Added
Driehaus Capital Management LLC1,493,791$39.9M0.33%−459,633−23.5%Reduced
Bellevue Group AG1,428,929$38.2M0.73%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,271,245$33.9M1.41%−1,561,622−55.1%Reduced
Viking Global Investors LPSuperinvestorViking Global Investors1,224,986$32.7M0.11%−256,160−17.3%Reduced
MPM Oncology Impact Management LP1,079,316$28.8M4.09%+162,150+17.7%Added
Artisan Partners Limited Partnership1,071,596$28.6M0.04%+70,964+7.1%Added
New Leaf Venture Partners, L.L.C.1,030,161$27.5M36.77%−523,500−33.7%Reduced
Millennium Management LLC888,968$23.7M0.02%−98,062−9.9%Reduced
First Light Asset Management, LLC780,639$20.8M1.99%+780,639New
American Century Companies Inc770,353$20.6M0.01%−164,034−17.6%Reduced
Siren, L.L.C.734,343$19.6M0.87%+330,230+81.7%Added
Dimensional Fund Advisors LP729,923$19.5M0.00%+3,052+0.4%Added
Deep Track Capital, LP710,421$19.0M0.71%−390,115−35.4%Reduced
D. E. Shaw & Co., Inc.686,371$18.3M0.02%+231,023+50.7%Added
Northern Trust Corp611,306$16.3M0.00%+35,426+6.2%Added
Foresite Capital Management VI LLC585,000$15.6M6.96%+585,000New
Woodline Partners LP567,218$15.1M0.10%+39,379+7.5%Added
Integral Health Asset Management, LLC550,000$14.7M1.30%+550,000New
Charles Schwab Investment Management Inc537,359$14.3M0.00%+15,273+2.9%Added
Opaleye Management Inc.480,000$12.8M2.24%−42,500−8.1%Reduced
Citadel Advisors LLC469,451$12.5M0.01%−68,798−12.8%Reduced
Morgan Stanley436,430$11.7M0.00%+18,299+4.4%Added
Nuveen Asset Management, LLC428,858$11.5M0.00%+158,452+58.6%Added
Sofinnova Investments, Inc.402,773$10.8M0.79%+18,006+4.7%Added
Logos Global Management LP400,000$10.7M1.25%−50,000−11.1%Reduced
Parkman Healthcare Partners LLC381,173$10.2M1.36%−275,897−42.0%Reduced
Qube Research & Technologies Ltd369,442$9.86M0.02%+237,550+180.1%Added
Goldman Sachs Group Inc346,891$9.26M0.00%−135,334−28.1%Reduced
Amundi341,687$8.69M0.00%+191,267+127.2%Added
Pictet Asset Management Holding SA301,241$8.04M0.01%+301,241New
Granahan Investment Management Inc300,013$8.01M0.33%−211,892−41.4%Reduced
Tang Capital Management LLC300,000$8.01M0.53%+300,000New
Voya Investment Management LLC284,148$7.59M0.01%−23,694−7.7%Reduced
UBS Asset Management Americas Inc279,125$7.45M0.00%+194,831+231.1%Added
Deutsche Bank AG275,837$7.36M0.00%+57,955+26.6%Added
Schonfeld Strategic Advisors LLC268,509$7.17M0.05%−277,037−50.8%Reduced
Candriam Luxembourg S.C.A.253,965$6.78M0.04%−40,659−13.8%Reduced
FMR LLC248,036$6.62M0.00%−405,172−62.0%Reduced
Adage Capital Partners GP, L.L.C.240,000$6.41M0.01%+218,491+1,015.8%Added
Kennedy Capital Management, Inc.236,642$6.32M0.14%+9,619+4.2%Added
Cubist Systematic Strategies, LLC219,549$5.86M0.10%+219,549New
Bank of New York Mellon Corp211,056$5.64M0.00%+284+0.1%Added
Wellington Management Group LLP202,893$5.42M0.00%−2,428−1.2%Reduced
Walleye Capital LLC198,662$5.30M0.05%−43,589−18.0%Reduced
Moody Aldrich Partners LLC187,932$5.02M0.93%+36,775+24.3%Added
DAFNA Capital Management LLC187,140$5.00M1.27%−40,766−17.9%Reduced
Soleus Capital Management, L.P.183,300$4.89M0.37%+183,300New
Standard Life Aberdeen plc178,043$4.75M0.01%−78,602−30.6%Reduced
Barclays PLC133,657$3.57M0.00%+14,307+12.0%Added
StemPoint Capital LP132,706$3.54M0.89%+112,806+566.9%Added
Two Sigma Investments, LP131,667$3.52M0.01%−129,791−49.6%Reduced
JPMorgan Chase & Co124,435$3.32M0.00%−34,071−21.5%Reduced
Algert Global LLC110,259$2.94M0.07%+100,859+1,073.0%Added
J. Goldman & Co LP107,278$2.86M0.10%+95,812+835.6%Added
Point72 Asset Management, L.P.106,562$2.85M0.01%+106,562New
Rhumbline Advisers102,397$2.73M0.00%+1,525+1.5%Added
Schroder Investment Management Group93,061$2.52M0.00%+93,061New
UBS Group AG92,066$2.46M0.00%+16,761+22.3%Added
EAM Investors, LLC91,333$2.44M0.35%−33,851−27.0%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH90,031$2.40M0.00%+90,031New
Acuta Capital Partners, LLC87,658$2.34M2.35%+24,658+39.1%Added
Ally Bridge Group (NY) LLC83,176$2.22M1.90%−104,519−55.7%Reduced
HighVista Strategies LLC82,732$2.21M0.82%−6,106−6.9%Reduced
Exome Asset Management LLC81,473$2.18M1.64%+21,573+36.0%Added
Ensign Peak Advisors, Inc80,509$2.15M0.00%+80,509New
Harvest Investment Services, LLC79,381$2.12M0.52%+79,381New
Citigroup Inc78,497$2.10M0.00%+2,656+3.5%Added
Alliancebernstein L.P.77,260$2.06M0.00%+1,300+1.7%Added
Alps Advisors Inc76,567$2.04M0.01%+7,661+11.1%Added
Trexquant Investment LP74,781$2.00M0.02%+74,781New
Bridger Management, LLC74,700$1.99M1.07%00.0%Unchanged
Swiss National Bank73,600$1.97M0.00%00.0%Unchanged
Quantum Private Wealth, LLC73,524$1.96M0.63%+100+0.1%Added
New York State Common Retirement Fund71,366$1.91M0.00%+4,284+6.4%Added
Polar Asset Management Partners Inc.64,279$1.72M0.03%−93,300−59.2%Reduced
State of Wisconsin Investment Board61,521$1.64M0.00%−10,263−14.3%Reduced
Bamco Inc60,000$1.60M0.00%+60,000New
Jump Financial, LLC55,178$1.47M0.03%−76,628−58.1%Reduced
SEI Investments Co52,178$1.39M0.00%−432−0.8%Reduced
DekaBank Deutsche Girozentrale80,000$1.36M0.00%00.0%Unchanged
Legal & General Group Plc50,292$1.34M0.00%+6,635+15.2%Added
Simplex Trading, LLC50,130$1.34M0.04%−23,900−32.3%Reduced
Bank of America Corp48,907$1.31M0.00%−259,144−84.1%Reduced
Norges Bank47,755$1.28M0.00%00.0%Unchanged
Verition Fund Management LLC46,391$1.24M0.01%+46,391New
MetLife Investment Management44,612$1.19M0.01%+2,341+5.5%Added