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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
129
+13 vs. Q4 2023
Shares held
91.6M
+12.0M (+15.0%) vs. Q4 2023
Total value
$1.67B
+$799.6M (+91.8%) vs. Q4 2023
New holders
32
60 more added
Sold out
19
28 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 129 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2024: $1.67B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2023.

Institutions holding EWTX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC15,021,721$274.0M5.37%+454,545+3.1%Added
Ra Capital Management, L.P.8,909,091$162.5M2.07%+8,909,091New
FMR LLC6,365,724$116.1M0.01%−126,789−2.0%Reduced
Baker Bros. Advisors LP5,840,059$106.5M1.34%+2,727,273+87.6%Added
BlackRock Inc.5,167,006$94.2M0.00%+1,859,896+56.2%Added
Vanguard Group Inc4,017,433$73.3M0.00%+1,892,053+89.0%Added
Viking Global Investors LPSuperinvestorViking Global Investors3,339,146$60.9M0.23%−2,820,000−45.8%Reduced
Frazier Life Sciences Management, L.P.3,303,567$60.3M2.54%+636,364+23.9%Added
Cormorant Asset Management, LP3,006,534$54.8M2.42%+454,545+17.8%Added
Deerfield Management Company, L.P. (Series C)2,874,586$52.4M0.91%−1,058,551−26.9%Reduced
Citadel Advisors LLC2,719,291$49.6M0.05%+133,361+5.2%Added
Paradigm Biocapital Advisors LP2,446,373$44.6M1.57%+2,446,373New
Perceptive Advisors LLC2,319,646$42.3M0.75%+1,764,091+317.5%Added
TCG Crossover Management, LLC2,272,728$41.5M3.28%+2,272,728New
VR Adviser, LLC1,818,182$33.2M1.58%+1,818,182New
Janus Henderson Group PLC1,805,312$32.9M0.02%+590,299+48.6%Added
Goldman Sachs Group Inc1,747,844$31.9M0.01%+865,948+98.2%Added
New Leaf Venture Partners, L.L.C.1,553,661$28.3M24.80%00.0%Unchanged
Geode Capital Management, LLC1,369,897$25.0M0.00%+422,851+44.6%Added
Driehaus Capital Management LLC1,267,819$23.1M0.23%+872,750+220.9%Added
EcoR1 Capital, LLC1,250,385$22.8M0.58%−2,242,809−64.2%Reduced
State Street Corp1,211,476$22.1M0.00%+318,767+35.7%Added
Artal Group S.A.811,718$14.8M0.38%+811,718New
Opaleye Management Inc.665,000$12.1M2.64%−34,000−4.9%Reduced
Parkman Healthcare Partners LLC653,653$11.9M1.46%+2,028+0.3%Added
Granahan Investment Management Inc608,012$11.1M0.39%−466,896−43.4%Reduced
American Century Companies Inc559,334$10.2M0.01%−211,118−27.4%Reduced
Millennium Management LLC532,255$9.71M0.01%+400,900+305.2%Added
Northern Trust Corp499,520$9.11M0.00%+136,277+37.5%Added
Charles Schwab Investment Management Inc497,162$9.07M0.00%+166,103+50.2%Added
D. E. Shaw & Co., Inc.473,680$8.64M0.01%+441,730+1,382.6%Added
Wellington Management Group LLP472,903$8.63M0.00%+131,997+38.7%Added
MPM Oncology Impact Management LP441,259$8.05M1.29%+441,259New
Woodline Partners LP405,132$7.39M0.07%+920+0.2%Added
Two Sigma Investments, LP392,735$7.16M0.02%+223,193+131.6%Added
Morgan Stanley374,718$6.83M0.00%+149,539+66.4%Added
Nuveen Asset Management, LLC338,004$6.17M0.00%+184,712+120.5%Added
Candriam Luxembourg S.C.A.329,000$6.00M0.04%+21,000+6.8%Added
DAFNA Capital Management LLC306,197$5.59M1.27%−143,187−31.9%Reduced
Dimensional Fund Advisors LP299,288$5.46M0.00%+37,050+14.1%Added
Kennedy Capital Management, Inc.293,265$5.35M0.11%−49,599−14.5%Reduced
Schonfeld Strategic Advisors LLC284,600$5.19M0.04%−34,500−10.8%Reduced
Bank of New York Mellon Corp212,265$3.87M0.00%+66,095+45.2%Added
ADAR1 Capital Management, LLC180,911$3.30M0.90%+180,911New
Voloridge Investment Management, LLC175,901$3.21M0.01%+175,901New
Trexquant Investment LP126,332$2.30M0.05%+70,741+127.3%Added
Cubist Systematic Strategies, LLC103,208$1.88M0.02%+101,479+5,869.2%Added
Two Sigma Advisers, LP92,400$1.69M0.00%+51,500+125.9%Added
Barclays PLC87,244$1.59M0.00%−691,672−88.8%Reduced
Rhumbline Advisers84,228$1.54M0.00%+19,895+30.9%Added
DekaBank Deutsche Girozentrale80,000$1.44M0.00%00.0%Unchanged
UBS Oconnor LLC75,097$1.37M0.04%−39,588−34.5%Reduced
Gsa Capital Partners LLP74,511$1.36M0.11%+21,851+41.5%Added
UBS Group AG74,118$1.35M0.00%+74,118New
New York State Common Retirement Fund68,698$1.25M0.00%−1,995−2.8%Reduced
Swiss National Bank67,300$1.23M0.00%+17,200+34.3%Added
Quantum Private Wealth, LLC66,674$1.22M0.45%+3,455+5.5%Added
Alps Advisors Inc65,672$1.20M0.01%+22,446+51.9%Added
Lighthouse Investment Partners, LLC60,881$1.11M0.07%+60,881New
Alliancebernstein L.P.56,100$1.02M0.00%+18,680+49.9%Added
Marshall Wace, LLP54,617$996.2K0.00%+54,617New
Bank of America Corp53,763$980.6K0.00%−8,505−13.7%Reduced
Renaissance Technologies LLC45,400$828.0K0.00%−19,300−29.8%Reduced
JPMorgan Chase & Co42,833$781.3K0.00%+2,770+6.9%Added
Citigroup Inc36,944$673.9K0.00%+29,683+408.8%Added
California State Teachers Retirement System36,467$665.2K0.00%+6,847+23.1%Added
UBS Asset Management Americas Inc32,413$591.2K0.00%+8,800+37.3%Added
Manufacturers Life Insurance Company, The30,580$557.8K0.00%+13,322+77.2%Added
MetLife Investment Management29,935$546.0K0.00%+6,580+28.2%Added
Legal & General Group Plc28,491$519.7K0.00%+11,834+71.0%Added
American International Group, Inc.28,418$518.3K0.00%+7,151+33.6%Added
Jane Street Group, LLC27,146$495.1K0.00%−16,993−38.5%Reduced
Susquehanna International Group, LLP26,870$490.1K0.00%−27,566−50.6%Reduced
Graham Capital Management, L.P.26,842$489.6K0.01%+26,842New
PDT Partners, LLC26,359$480.8K0.05%−2,900−9.9%Reduced
Deutsche Bank AG25,274$461.0K0.00%+4,864+23.8%Added
Squarepoint Ops LLC24,854$453.3K0.00%+13,244+114.1%Added
Invesco Ltd.21,146$385.7K0.00%+4,618+27.9%Added
Wells Fargo & Company20,431$372.7K0.00%+7,255+55.1%Added
Credit Suisse AG20,166$367.8K0.00%+2,867+16.6%Added
Franklin Resources Inc20,005$364.9K0.00%+20,005New
State of Wisconsin Investment Board19,601$357.5K0.00%+19,601New
Denali Advisors LLC19,200$350.2K0.10%+19,200New
Voya Investment Management LLC18,296$333.7K0.00%+111+0.6%Added
China Universal Asset Management Co., Ltd.17,881$326.1K0.04%+10,543+143.7%Added
ProShare Advisors LLC16,885$308.0K0.00%+5,748+51.6%Added
Principal Financial Group Inc16,765$305.8K0.00%+365+2.2%Added
Price T Rowe Associates Inc16,424$300.0K0.00%−109,647−87.0%Reduced
Castleview Partners, LLC16,204$295.6K0.17%+16,204New
Y-Intercept (Hong Kong) Ltd14,903$271.8K0.02%+14,903New
EntryPoint Capital, LLC14,216$259.3K0.23%+496+3.6%Added
XTX Topco Ltd14,049$256.3K0.03%−3,094−18.0%Reduced
Oxford Asset Management LLP13,615$248.3K0.27%+13,615New
Nantahala Capital Management, LLC13,371$243.9K0.02%+13,371New
Corton Capital Inc.13,042$237.9K0.09%−7,176−35.5%Reduced
Entropy Technologies, LP12,665$231.0K0.02%+12,665New
STRS Ohio12,600$229.0K0.00%+12,600New
Fox Run Management, L.L.C.10,814$197.2K0.04%+10,814New
SFMG, LLC10,000$182.4K0.02%00.0%Unchanged
Qube Research & Technologies Ltd9,002$164.2K0.00%+6,976+344.3%Added