Edgewise Therapeutics, Inc.
EWTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001710072
In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Edgewise Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 173
- −5 vs. Q2 2025
- Shares held
- 112.0M
- −6.73M (−5.7%) vs. Q2 2025
- Total value
- $1.82B
- +$259.7M (+16.7%) vs. Q2 2025
- New holders
- 17
- 59 more added
- Sold out
- 22
- 62 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 226 | $4.82B |
| Q1 2026 | 214 | $3.72B |
| Q4 2025 | 199 | $3.02B |
| Q3 2025 | 173 | $1.82B |
| Q2 2025 | 179 | $1.56B |
| Q1 2025 | 193 | $2.32B |
| Q4 2024 | 201 | $2.64B |
| Q3 2024 | 177 | $2.71B |
| Q2 2024 | 140 | $1.83B |
| Q1 2024 | 129 | $1.67B |
| Q4 2023 | 116 | $871.4M |
| Q3 2023 | 85 | $392.2M |
| Q2 2023 | 95 | $538.8M |
| Q1 2023 | 85 | $443.1M |
| Q4 2022 | 90 | $594.1M |
| Q3 2022 | 94 | $633.5M |
| Q2 2022 | 78 | $405.7M |
| Q1 2022 | 72 | $523.5M |
| Q4 2021 | 58 | $769.4M |
| Q3 2021 | 48 | $795.8M |
| Q2 2021 | 46 | $1.03B |
| Q1 2021 | 31 | $1.48B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 15,518,492 | $251.7M | 6.04% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 10,428,437 | $169.1M | 2.08% | +525,804+5.3% | Added |
| Baker Bros. Advisors LP | 7,305,940 | $118.5M | 0.86% | 00.0% | Unchanged |
| BlackRock, Inc. | 6,351,487 | $103.0M | 0.00% | −429,559−6.3% | Reduced |
| Paradigm Biocapital Advisors LP | 6,170,131 | $100.1M | 2.96% | +27,787+0.5% | Added |
| Novo Holdings A/S | 5,350,000 | $86.8M | 5.59% | 00.0% | Unchanged |
| Braidwell LP | 5,210,831 | $84.5M | 2.51% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 4,979,331 | $80.8M | 0.04% | −524,018−9.5% | Reduced |
| Vanguard Group Inc | 4,803,941 | $77.9M | 0.00% | −37,559−0.8% | Reduced |
| Cormorant Asset Management, LP | 4,010,000 | $65.0M | 4.49% | −241,992−5.7% | Reduced |
| Siren, L.L.C. | 3,897,099 | $63.2M | 2.47% | +736,801+23.3% | Added |
| Perceptive Advisors LLC | 3,795,894 | $61.6M | 1.78% | −844,055−18.2% | Reduced |
| Bellevue Group AG | 2,775,997 | $45.0M | 0.94% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 2,228,285 | $36.1M | 0.26% | +126,504+6.0% | Added |
| MPM Oncology Impact Management LP | 1,720,741 | $27.9M | 4.57% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,717,641 | $27.9M | 0.00% | −79,574−4.4% | Reduced |
| State Street Corp | 1,699,909 | $27.6M | 0.00% | −81,592−4.6% | Reduced |
| Integral Health Asset Management, LLC | 1,500,000 | $24.3M | 1.77% | +500,000+50.0% | Added |
| First Light Asset Management, LLC | 1,414,994 | $23.0M | 2.16% | −299,025−17.4% | Reduced |
| Dimensional Fund Advisors LP | 1,183,136 | $19.2M | 0.00% | +134,200+12.8% | Added |
| American Century Companies Inc | 1,095,473 | $17.8M | 0.01% | +312,307+39.9% | Added |
| New Leaf Venture Partners, L.L.C. | 1,030,161 | $16.7M | 38.82% | 00.0% | Unchanged |
| Morgan Stanley | 869,678 | $14.1M | 0.00% | +141,964+19.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 765,694 | $12.4M | 0.19% | −1,301,626−63.0% | Reduced |
| Millennium Management LLC | 725,425 | $11.8M | 0.01% | −196,540−21.3% | Reduced |
| Artisan Partners Limited Partnership | 718,175 | $11.6M | 0.02% | −660,893−47.9% | Reduced |
| D. E. Shaw & Co., Inc. | 677,561 | $11.0M | 0.01% | +82,129+13.8% | Added |
| Standard Life Aberdeen plc | 619,878 | $10.1M | 0.02% | +176,559+39.8% | Added |
| Charles Schwab Investment Management Inc | 597,603 | $9.69M | 0.00% | +18,499+3.2% | Added |
| Northern Trust Corp | 587,882 | $9.54M | 0.00% | −15,016−2.5% | Reduced |
| Eventide Asset Management, LLC | 568,310 | $9.22M | 0.15% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 555,713 | $9.01M | 0.01% | +55,796+11.2% | Added |
| Parkman Healthcare Partners LLC | 550,173 | $8.92M | 0.98% | −97,158−15.0% | Reduced |
| Citigroup Inc | 538,453 | $8.73M | 0.01% | −186,446−25.7% | Reduced |
| Goldman Sachs Group Inc | 527,827 | $8.56M | 0.00% | −103,916−16.4% | Reduced |
| Sofinnova Investments, Inc. | 520,240 | $8.44M | 0.52% | −196,633−27.4% | Reduced |
| Eversept Partners, LP | 502,234 | $8.15M | 0.62% | +109,495+27.9% | Added |
| Opaleye Management Inc. | 500,000 | $8.11M | 1.15% | +10,000+2.0% | Added |
| Victory Capital Management Inc | 498,646 | $8.09M | 0.01% | +55,809+12.6% | Added |
| Tang Capital Management LLC | 431,300 | $7.00M | 0.27% | 00.0% | Unchanged |
| Granahan Investment Management Inc | 339,617 | $5.51M | 0.23% | −65,861−16.2% | Reduced |
| Bank of America Corp | 321,132 | $5.21M | 0.00% | +66,703+26.2% | Added |
| Sio Capital Management, LLC | 307,181 | $4.98M | 1.26% | −232,549−43.1% | Reduced |
| Kynam Capital Management, LP | 253,979 | $4.12M | 0.31% | 00.0% | Unchanged |
| FMR LLC | 253,325 | $4.11M | 0.00% | −217,392−46.2% | Reduced |
| Kennedy Capital Management, Inc. | 250,622 | $4.07M | 0.09% | −1,902−0.8% | Reduced |
| Barclays PLC | 234,650 | $3.81M | 0.00% | −46,600−16.6% | Reduced |
| Woodline Partners LP | 224,190 | $3.64M | 0.02% | −872,673−79.6% | Reduced |
| Candriam Luxembourg S.C.A. | 221,159 | $3.59M | 0.02% | −2,831−1.3% | Reduced |
| Neuberger Berman Group LLC | 219,646 | $3.56M | 0.00% | +54,111+32.7% | Added |
| DAFNA Capital Management LLC | 213,736 | $3.47M | 0.86% | −24,404−10.2% | Reduced |
| HighVista Strategies LLC | 208,101 | $3.38M | 0.83% | +138,378+198.5% | Added |
| Bank of New York Mellon Corp | 204,242 | $3.31M | 0.00% | −8,616−4.0% | Reduced |
| Exome Asset Management LLC | 173,439 | $2.81M | 1.86% | +48,969+39.3% | Added |
| Nuveen, LLC | 172,707 | $2.80M | 0.00% | −144,466−45.5% | Reduced |
| Deutsche Bank AG | 154,896 | $2.51M | 0.00% | +7,371+5.0% | Added |
| Schroder Investment Management Group | 151,062 | $2.38M | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 139,112 | $2.26M | 0.00% | −52,494−27.4% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 132,503 | $2.15M | 0.00% | +325+0.2% | Added |
| Wellington Management Group LLP | 114,531 | $1.86M | 0.00% | +1,961+1.7% | Added |
| UBS Group AG | 114,128 | $1.85M | 0.00% | −56,854−33.3% | Reduced |
| Gsa Capital Partners LLP | 113,243 | $1.84M | 0.15% | +85,967+315.2% | Added |
| Quantum Private Wealth, LLC | 105,874 | $1.72M | 0.50% | +5,100+5.1% | Added |
| Rhumbline Advisers | 104,829 | $1.70M | 0.00% | −7,654−6.8% | Reduced |
| Swiss National Bank | 101,900 | $1.65M | 0.00% | +11,900+13.2% | Added |
| DekaBank Deutsche Girozentrale | 80,000 | $1.55M | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 83,437 | $1.35M | 0.00% | −10,371−11.1% | Reduced |
| Moody Aldrich Partners LLC | 82,941 | $1.35M | 0.26% | −16,907−16.9% | Reduced |
| Jump Financial, LLC | 80,825 | $1.31M | 0.02% | −40,880−33.6% | Reduced |
| Alliancebernstein L.P. | 77,260 | $1.25M | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 75,276 | $1.22M | 0.00% | +75,276 | New |
| Jane Street Group, LLC | 69,998 | $1.14M | 0.00% | +19,813+39.5% | Added |
| JPMorgan Chase & Co | 68,720 | $1.11M | 0.00% | −8,896−11.5% | Reduced |
| Invesco Ltd. | 66,056 | $1.07M | 0.00% | +9,898+17.6% | Added |
| Federated Hermes, Inc. | 59,256 | $961.1K | 0.00% | −257,244−81.3% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 57,300 | $929.4K | 0.02% | +57,300 | New |
| Legal & General Group Plc | 55,941 | $907.4K | 0.00% | +3,634+6.9% | Added |
| HighMark Wealth Management LLC | 53,179 | $862.6K | 0.38% | +1,114+2.1% | Added |
| HRT Financial LP | 52,203 | $846.0K | 0.00% | +52,203 | New |
| Schonfeld Strategic Advisors LLC | 51,989 | $843.3K | 0.01% | −115,351−68.9% | Reduced |
| Price T Rowe Associates Inc | 51,386 | $834.0K | 0.00% | +704+1.4% | Added |
| Alps Advisors Inc | 51,112 | $829.0K | 0.00% | −5,686−10.0% | Reduced |
| California State Teachers Retirement System | 50,793 | $823.9K | 0.00% | +13,915+37.7% | Added |
| Prelude Capital Management, LLC | 49,205 | $798.1K | 0.06% | +10,396+26.8% | Added |
| Franklin Resources Inc | 48,220 | $782.1K | 0.00% | +2,414+5.3% | Added |
| Susquehanna International Group, LLP | 45,635 | $740.2K | 0.00% | −69,635−60.4% | Reduced |
| MetLife Investment Management | 43,883 | $711.8K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 42,196 | $684.4K | 0.00% | +3,812+9.9% | Added |
| Algert Global LLC | 40,963 | $664.4K | 0.01% | +6,240+18.0% | Added |
| ADAR1 Capital Management, LLC | 40,000 | $648.8K | 0.06% | 00.0% | Unchanged |
| SEI Investments Co | 39,095 | $634.1K | 0.00% | −4,543−10.4% | Reduced |
| Handelsbanken Fonder AB | 38,400 | $623.0K | 0.00% | +9,700+33.8% | Added |
| State of Wisconsin Investment Board | 36,619 | $594.0K | 0.00% | −17,400−32.2% | Reduced |
| Manufacturers Life Insurance Company, The | 35,538 | $576.4K | 0.00% | −2,790−7.3% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 31,350 | $508.5K | 0.00% | −8,628−21.6% | Reduced |
| Intech Investment Management LLC | 29,179 | $473.3K | 0.00% | −14,886−33.8% | Reduced |
| Optimize Financial Inc | 27,283 | $442.5K | 0.23% | +27,283 | New |
| Two Sigma Investments, LP | 26,266 | $426.0K | 0.00% | +26,266 | New |
| Trexquant Investment LP | 22,625 | $367.0K | 0.00% | +22,625 | New |
| Citadel Advisors LLC | 22,317 | $362.0K | 0.00% | −302,932−93.1% | Reduced |