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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Edgewise Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
−5 vs. Q2 2025
Shares held
112.0M
−6.73M (−5.7%) vs. Q2 2025
Total value
$1.82B
+$259.7M (+16.7%) vs. Q2 2025
New holders
17
59 more added
Sold out
22
62 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 173 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ3 2025: $1.82B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding EWTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
SummitTX Capital, L.P.20,782$337.1K0.01%−598−2.8%Reduced
Fox Run Management, L.L.C.20,471$332.0K0.05%+20,471New
Police & Firemen's Retirement System of New Jersey18,865$306.0K0.00%+1,509+8.7%Added
Graham Capital Management, L.P.18,789$304.8K0.01%−21,575−53.5%Reduced
China Universal Asset Management Co., Ltd.18,466$299.5K0.02%−2,654−12.6%Reduced
Creative Planning18,036$292.5K0.00%+1,126+6.7%Added
State Board of Administration of Florida Retirement System16,870$273.6K0.00%00.0%Unchanged
Royal Bank of Canada15,695$254.0K0.00%+8,001+104.0%Added
Arizona State Retirement System15,549$252.2K0.00%+1,804+13.1%Added
ProShare Advisors LLC15,291$248.0K0.00%−3,597−19.0%Reduced
ExodusPoint Capital Management, LP14,672$238.0K0.00%−30,583−67.6%Reduced
BNP Paribas Arbitrage, SA14,297$231.9K0.00%+6,104+74.5%Added
Quest Partners LLC14,274$231.5K0.02%−7,116−33.3%Reduced
Raymond James Financial Inc13,379$217.0K0.00%+11,821+758.7%Added
Teacher Retirement System of Texas12,815$207.9K0.00%+169+1.3%Added
Voya Investment Management LLC12,417$201.4K0.00%−7,496−37.6%Reduced
Profund Advisors LLC11,809$191.5K0.01%−3,276−21.7%Reduced
Campbell & CO Investment Adviser LLC11,140$180.7K0.01%−103,041−90.2%Reduced
Glenmede Investment Management, LP11,137$180.6K0.00%−1,405−11.2%Reduced
Envestnet Asset Management Inc10,837$175.8K0.00%+10,837New
KLP Kapitalforvaltning AS10,600$171.9K0.00%00.0%Unchanged
SFMG, LLC10,000$162.2K0.01%00.0%Unchanged
SG Americas Securities, LLC9,881$160.0K0.00%+9,881New
Simplex Trading, LLC7,590$123.0K0.00%+3,407+81.4%Added
Virtus Investment Advisers, Inc.7,380$119.7K0.03%+1,282+21.0%Added
Russell Investments Group, Ltd.7,190$116.6K0.00%+7,166+29,858.3%Added
Zurcher Kantonalbank (Zurich Cantonalbank)6,863$111.3K0.00%−210−3.0%Reduced
Ameritas Investment Partners, Inc.5,638$91.4K0.00%−1,956−25.8%Reduced
Canada Pension Plan Investment Board4,500$73.0K0.00%+1,100+32.4%Added
Mirae Asset Global Investments Co., Ltd.4,073$66.1K0.00%+11+0.3%Added
Public Employees Retirement Association of Colorado2,849$46.0K0.00%00.0%Unchanged
Amalgamated Bank2,521$41.0K0.00%00.0%Unchanged
Bessemer Group Inc2,350$38.0K0.00%+2,165+1,170.3%Added
Steward Partners Investment Advisory, LLC2,304$37.4K0.00%+2,304New
US Bancorp2,292$37.2K0.00%+283+14.1%Added
GF Fund Management Co. Ltd.2,266$36.8K0.00%−158−6.5%Reduced
Tower Research Capital LLC (TRC)1,639$26.6K0.00%−7,509−82.1%Reduced
Winthrop Capital Management, LLC1,377$22.0K0.01%00.0%Unchanged
GAMMA Investing LLC1,158$18.8K0.00%−8−0.7%Reduced
Nisa Investment Advisors, LLC874$14.2K0.00%−70−7.4%Reduced
Kayne Anderson Rudnick Investment Management LLC622$10.1K0.00%+622New
Crowley Wealth Management, Inc.560$9.08K0.01%00.0%Unchanged
Farther Finance Advisors, LLC558$9.05K0.00%+184+49.2%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.521$8.00K0.00%+67+14.8%Added
Optiver Holding B.V.468$7.59K0.00%+468New
Advisor Group Holdings, Inc.447$7.21K0.00%−671−60.0%Reduced
Daiwa Securities Group Inc.344$6.00K0.00%00.0%Unchanged
Signaturefd, LLC363$5.89K0.00%00.0%Unchanged
Massmutual Trust Co FSB344$5.58K0.00%+111+47.6%Added
SBI Securities Co., Ltd.207$3.36K0.00%00.0%Unchanged
Sterling Capital Management LLC163$2.64K0.00%−8−4.7%Reduced
Fortitude Family Office, LLC160$2.60K0.00%00.0%Unchanged
Advisory Services Network, LLC151$2.46K0.00%+151New
EverSource Wealth Advisors, LLC142$2.30K0.00%+81+132.8%Added
Rothschild Investment LLC135$2.19K0.00%−25−15.6%Reduced
Larson Financial Group LLC135$2.19K0.00%+135New
CWM, LLC132$2.00K0.00%+23+21.1%Added
SRS Capital Advisors, Inc.106$1.72K0.00%+58+120.8%Added
BFSG, LLC100$1.62K0.00%00.0%Unchanged
Parallel Advisors, LLC95$1.54K0.00%00.0%Unchanged
Versant Capital Management, Inc95$1.54K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.67$1.09K0.00%+18+36.7%Added
National Bank of Canada40$6490.00%00.0%Unchanged
Comerica Bank35$5810.00%00.0%Unchanged
Parkside Financial Bank & Trust35$5690.00%00.0%Unchanged
Allworth Financial LP33$5360.00%+33New
Principal Securities, Inc.27$4380.00%00.0%Unchanged
Smartleaf Asset Management LLC27$4250.00%+1+3.8%Added
Montag A & Associates Inc16$2600.00%+16New
IFP Advisors, Inc4$650.00%+4Added
Clearstead Advisors, LLC4$650.00%+4New
American National Bank2$320.00%00.0%Unchanged
Covestor Ltd8$00.00%00.0%Unchanged
Polar Capital Holdings Plc0$00.00%−975,000−100.0%Sold out
Foresite Capital Management VI LLC0$00.00%−585,000−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−284,551−100.0%Sold out
Walleye Capital LLC0$00.00%−86,882−100.0%Sold out
Twinbeech Capital LP0$00.00%−78,280−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−76,493−100.0%Sold out
XTX Topco Ltd0$00.00%−60,739−100.0%Sold out
UBS Oconnor LLC0$00.00%−55,292−100.0%Sold out
Verition Fund Management LLC0$00.00%−44,069−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−41,663−100.0%Sold out
Quantbot Technologies LP0$00.00%−41,463−100.0%Sold out
Skandinaviska Enskilda Banken AB (publ)0$00.00%−37,591−100.0%Sold out
Engineers Gate Manager LP0$00.00%−34,909−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−27,042−100.0%Sold out
Numerai GP LLC0$00.00%−22,353−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−13,561−100.0%Sold out
Nebula Research & Development LLC0$00.00%−13,219−100.0%Sold out
HSBC Holdings PLC0$00.00%−10,712−100.0%Sold out
STRS Ohio0$00.00%−6,100−100.0%Sold out
Skopos Labs, Inc.0$00.00%−1,314−100.0%Sold out
Quarry LP0$00.00%−311−100.0%Sold out
Riggs Asset Managment Co. Inc.0$00.00%−49−100.0%Sold out
Norges Bank––––Not filed