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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
72
+14 vs. Q4 2021
Shares held
54.0M
+3.63M (+7.2%) vs. Q4 2021
Total value
$523.5M
−$245.9M (−32.0%) vs. Q4 2021
New holders
18
25 more added
Sold out
4
18 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 72 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2022: $523.5M
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding EWTX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC13,944,680$135.3M2.20%00.0%Unchanged
Novo Holdings A/S5,587,207$54.2M2.86%00.0%Unchanged
Cormorant Asset Management, LP4,682,874$45.4M3.49%+1,116,973+31.3%Added
Deerfield Management Company, L.P. (Series C)3,933,137$38.2M0.85%00.0%Unchanged
Viking Global Investors LPSuperinvestorViking Global Investors2,727,249$26.5M0.11%00.0%Unchanged
Citadel Advisors LLC2,639,800$25.6M0.03%+181,359+7.4%Added
Ra Capital Management, L.P.2,613,623$25.4M0.55%00.0%Unchanged
FMR LLC2,521,450$24.5M0.00%+21,351+0.9%Added
EcoR1 Capital, LLC2,359,808$22.9M0.72%+1,080,633+84.5%Added
BlackRock Inc.2,055,160$19.9M0.00%+7,557+0.4%Added
New Leaf Venture Partners, L.L.C.1,553,661$15.1M7.43%00.0%Unchanged
Janus Henderson Group PLC1,433,316$13.9M0.01%−93,019−6.1%Reduced
Vanguard Group Inc1,211,093$11.7M0.00%+11,693+1.0%Added
Ensign Peak Advisors, Inc662,526$6.43M0.01%+662,526New
State Street Corp564,210$5.47M0.00%+35,572+6.7%Added
Baker Bros. Advisors LP500,000$4.85M0.03%00.0%Unchanged
Geode Capital Management, LLC438,141$4.25M0.00%+46,559+11.9%Added
Woodline Partners LP360,093$3.49M0.06%−42,756−10.6%Reduced
DAFNA Capital Management LLC356,750$3.46M0.90%+356,750New
Price T Rowe Associates Inc349,775$3.39M0.00%+349,775New
Wellington Management Group LLP340,906$3.31M0.00%−340,906−50.0%Reduced
American Century Companies Inc304,881$2.96M0.00%+502+0.2%Added
Opaleye Management Inc.303,000$2.94M0.91%+303,000New
Norges Bank301,691$2.93M0.00%00.0%Unchanged
Northern Trust Corp293,952$2.85M0.00%−8,238−2.7%Reduced
Barclays PLC219,960$2.13M0.00%+219,960New
Logos Global Management LP213,744$2.07M0.27%−636,256−74.9%Reduced
Bank of New York Mellon Corp212,887$2.07M0.00%−1,626−0.8%Reduced
Charles Schwab Investment Management Inc145,305$1.41M0.00%+4,910+3.5%Added
Laurion Capital Management LP140,972$1.37M0.03%+140,972New
Goldman Sachs Group Inc132,166$1.28M0.00%+91,654+226.2%Added
Nuveen Asset Management, LLC110,115$1.15M0.00%+16,765+18.0%Added
Millennium Management LLC60,992$592.0K0.00%+60,992New
Tekla Capital Management LLC60,550$587.0K0.02%00.0%Unchanged
HighVista Strategies LLC59,733$579.0K0.37%+59,733New
State of Wisconsin Investment Board51,800$502.0K0.00%+35,800+223.7%Added
Cubist Systematic Strategies, LLC40,303$391.0K0.00%+40,303New
Rhumbline Advisers36,861$358.0K0.00%+6,350+20.8%Added
New York State Common Retirement Fund28,174$273.0K0.00%+9,714+52.6%Added
Bank of America Corp27,550$267.0K0.00%−1,236−4.3%Reduced
JPMorgan Chase & Co27,166$263.0K0.00%+5,156+23.4%Added
Walleye Capital LLC25,196$244.0K0.01%+25,196New
MetLife Investment Management23,355$226.5K0.00%+8,328+55.4%Added
Quantum Private Wealth, LLC22,242$215.0K0.09%+2,890+14.9%Added
Trexquant Investment LP22,212$215.0K0.01%+8,189+58.4%Added
Deutsche Bank AG21,996$214.0K0.00%−2,498−10.2%Reduced
Morgan Stanley21,975$214.0K0.00%+4,798+27.9%Added
UBS Group AG22,047$214.0K0.00%+22,047New
American International Group, Inc.19,210$186.0K0.00%−1,351−6.6%Reduced
DekaBank Deutsche Girozentrale19,800$183.0K0.00%+1,800+10.0%Added
Invesco Ltd.16,907$164.0K0.00%+390+2.4%Added
California State Teachers Retirement System16,617$161.0K0.00%−4,487−21.3%Reduced
Atom Investors LP15,781$153.0K0.07%+15,781New
Manufacturers Life Insurance Company, The15,730$152.6K0.00%−3,204−16.9%Reduced
Voya Investment Management LLC14,800$144.0K0.00%+1,213+8.9%Added
Dynamic Technology Lab Private Ltd12,923$125.0K0.01%+12,923New
ProShare Advisors LLC12,378$120.0K0.00%−3,015−19.6%Reduced
SFMG, LLC10,100$98.0K0.01%+10,100New
Virtus ETF Advisers LLC8,129$79.0K0.04%−475−5.5%Reduced
Amalgamated Bank6,299$61.0K0.00%+6,299New
Amalgamated Financial Corp.6,299$61.0K0.00%+6,299New
Legal & General Group Plc4,638$44.0K0.00%−13−0.3%Reduced
Wells Fargo & Company3,932$38.0K0.00%−13,920−78.0%Reduced
Royal Bank of Canada3,227$31.0K0.00%−12,425−79.4%Reduced
Ameritas Investment Partners, Inc.2,990$29.0K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,804$27.2K0.00%−8,328−74.8%Reduced
Citigroup Inc2,451$24.0K0.00%−8,885−78.4%Reduced
Tower Research Capital LLC (TRC)2,142$21.0K0.00%+861+67.2%Added
Quantbot Technologies LP800$7.00K0.00%+800New
Private Capital Group, LLC151$2.00K0.00%+151New
Daiwa Securities Group Inc.144$1.00K0.00%00.0%Unchanged
State of Wyoming33$00.00%+6+22.2%Added
Federated Hermes, Inc.0$00.00%−147,075−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−18,078−100.0%Sold out
Squarepoint Ops LLC0$00.00%−12,197−100.0%Sold out
STRS Ohio0$00.00%−2,900−100.0%Sold out