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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
193
−5 vs. Q4 2024
Shares held
105.3M
+6.78M (+6.9%) vs. Q4 2024
Total value
$2.32B
−$309.1M (−11.8%) vs. Q4 2024
New holders
33
68 more added
Sold out
38
62 more reduced

3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 193 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2025: $2.32B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding EWTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC15,021,721$330.5M7.94%00.0%Unchanged
Ra Capital Management, L.P.8,909,091$196.0M3.27%00.0%Unchanged
Perceptive Advisors LLC6,547,328$144.0M5.11%+3,861,791+143.8%Added
BlackRock, Inc.6,485,008$142.7M0.00%+5,993+0.1%Added
Baker Bros. Advisors LP6,155,940$135.4M1.50%00.0%Unchanged
Janus Henderson Group PLC5,282,154$122.9M0.07%+298,214+6.0%Added
Novo Holdings A/S5,350,000$117.7M8.95%+350,000+7.0%Added
Paradigm Biocapital Advisors LP4,394,556$96.7M4.45%−99,373−2.2%Reduced
Vanguard Group Inc4,294,404$94.5M0.00%−172,445−3.9%Reduced
Cormorant Asset Management, LP4,101,992$90.2M6.83%+695,458+20.4%Added
Braidwell LP2,458,808$54.1M1.90%+126,612+5.4%Added
Deerfield Management Company, L.P. (Series C)2,078,509$45.7M0.91%00.0%Unchanged
First Light Asset Management, LLC1,852,290$40.8M4.65%+1,071,651+137.3%Added
State Street Corp1,717,724$37.8M0.00%+2,179+0.1%Added
Siren, L.L.C.1,696,444$37.3M2.11%+962,101+131.0%Added
Geode Capital Management, LLC1,655,664$36.4M0.00%+55,093+3.4%Added
Bellevue Group AG1,428,929$31.4M0.70%00.0%Unchanged
Deep Track Capital, LP1,400,000$30.8M1.00%+689,579+97.1%Added
Driehaus Capital Management LLC1,375,742$30.3M0.29%−118,049−7.9%Reduced
MPM Oncology Impact Management LP1,105,444$24.3M4.18%+26,128+2.4%Added
Woodline Partners LP1,096,809$24.1M0.16%+529,591+93.4%Added
New Leaf Venture Partners, L.L.C.1,030,161$22.7M50.47%00.0%Unchanged
Artisan Partners Limited Partnership917,222$20.2M0.03%−154,374−14.4%Reduced
American Century Companies Inc779,766$17.2M0.01%+9,413+1.2%Added
Bank of America Corp695,426$15.3M0.00%+646,519+1,321.9%Added
Integral Health Asset Management, LLC675,000$14.8M1.65%+125,000+22.7%Added
Dimensional Fund Advisors LP667,499$14.7M0.00%−62,424−8.6%Reduced
Millennium Management LLC615,118$13.5M0.01%−273,850−30.8%Reduced
Northern Trust Corp606,692$13.3M0.00%−4,614−0.8%Reduced
Foresite Capital Management VI LLC585,000$12.9M7.05%00.0%Unchanged
Eventide Asset Management, LLC568,310$12.5M0.25%+568,310New
Charles Schwab Investment Management Inc521,261$11.5M0.00%−16,098−3.0%Reduced
Viking Global Investors LPSuperinvestorViking Global Investors490,035$10.8M0.03%−734,951−60.0%Reduced
Parkman Healthcare Partners LLC425,407$9.36M1.11%+44,234+11.6%Added
Morgan Stanley408,997$9.00M0.00%−27,433−6.3%Reduced
Qube Research & Technologies Ltd397,573$8.75M0.01%+28,131+7.6%Added
Opaleye Management Inc.395,000$8.69M1.93%−85,000−17.7%Reduced
Adage Capital Partners GP, L.L.C.390,000$8.58M0.02%+150,000+62.5%Added
Deutsche Bank AG376,060$8.27M0.00%+100,223+36.3%Added
Goldman Sachs Group Inc366,644$8.07M0.00%+19,753+5.7%Added
Readystate Asset Management LP361,233$7.95M0.40%+339,871+1,591.0%Added
Sofinnova Investments, Inc.342,218$7.53M0.57%−60,555−15.0%Reduced
Standard Life Aberdeen plc313,025$6.89M0.01%+134,982+75.8%Added
Pictet Asset Management Holding SA302,513$6.66M0.01%+1,272+0.4%Added
Tang Capital Management LLC300,000$6.60M0.37%00.0%Unchanged
Price T Rowe Associates Inc294,881$6.49M0.00%+265,831+915.1%Added
Voya Investment Management LLC280,735$6.18M0.01%−3,413−1.2%Reduced
Ikarian Capital, LLC280,000$6.16M2.01%+280,000New
Schonfeld Strategic Advisors LLC278,973$6.14M0.04%+10,464+3.9%Added
UBS Asset Management Americas Inc272,857$6.00M0.00%−6,268−2.2%Reduced
Polar Capital Holdings Plc250,000$5.50M0.03%+250,000New
UBS Group AG243,896$5.37M0.00%+151,830+164.9%Added
Candriam Luxembourg S.C.A.225,796$4.97M0.03%−28,169−11.1%Reduced
Kennedy Capital Management, Inc.224,700$4.94M0.12%−11,942−5.0%Reduced
Granahan Investment Management Inc217,667$4.79M0.24%−82,346−27.4%Reduced
Bank of New York Mellon Corp210,735$4.64M0.00%−321−0.2%Reduced
Caption Management, LLC204,500$4.50M0.21%+204,500New
Nuveen, LLC202,580$4.46M0.00%+202,580New
Amundi308,633$4.19M0.00%−33,054−9.7%Reduced
FMR LLC186,023$4.09M0.00%−62,013−25.0%Reduced
DAFNA Capital Management LLC183,140$4.03M1.14%−4,000−2.1%Reduced
Moody Aldrich Partners LLC182,095$4.01M0.84%−5,837−3.1%Reduced
StemPoint Capital LP180,255$3.97M1.27%+47,549+35.8%Added
Susquehanna International Group, LLP176,666$3.89M0.01%+144,953+457.1%Added
D. E. Shaw & Co., Inc.140,548$3.09M0.00%−545,823−79.5%Reduced
Jennison Associates LLC128,746$2.83M0.00%+128,746New
Balyasny Asset Management LLC120,910$2.66M0.01%+97,546+417.5%Added
Wellington Management Group LLP113,303$2.49M0.00%−89,590−44.2%Reduced
Rhumbline Advisers108,837$2.39M0.00%+6,440+6.3%Added
Barclays PLC108,562$2.39M0.00%−25,095−18.8%Reduced
EFG Asset Management (North America) Corp.104,386$2.30M0.38%+63,048+152.5%Added
Ally Bridge Group (NY) LLC102,650$2.26M2.04%+19,474+23.4%Added
Neuberger Berman Group LLC102,181$2.25M0.00%+102,181New
Twinbeech Capital LP100,826$2.22M0.04%+100,826New
Citadel Advisors LLC97,278$2.14M0.00%−372,173−79.3%Reduced
JPMorgan Chase & Co91,368$2.01M0.00%−33,067−26.6%Reduced
HighVista Strategies LLC91,207$2.01M0.77%+8,475+10.2%Added
Quantum Private Wealth, LLC90,724$2.00M0.75%+17,200+23.4%Added
Universal- Beteiligungs- und Servicegesellschaft mbH89,425$1.97M0.00%−606−0.7%Reduced
Acuta Capital Partners, LLC85,454$1.88M2.18%−2,204−2.5%Reduced
Boothbay Fund Management, LLC85,214$1.87M0.07%+85,214New
Schroder Investment Management Group79,151$1.84M0.00%−13,910−14.9%Reduced
Swiss National Bank82,600$1.82M0.00%+9,000+12.2%Added
Alliancebernstein L.P.77,260$1.70M0.00%00.0%Unchanged
Bridger Management, LLC74,700$1.64M0.82%00.0%Unchanged
Citigroup Inc74,307$1.63M0.00%−4,190−5.3%Reduced
Soleus Capital Management, L.P.72,300$1.59M0.12%−111,000−60.6%Reduced
New York State Common Retirement Fund71,450$1.57M0.00%+84+0.1%Added
Exome Asset Management LLC71,438$1.57M1.41%−10,035−12.3%Reduced
State of Wisconsin Investment Board71,132$1.56M0.00%+9,611+15.6%Added
Alps Advisors Inc67,975$1.50M0.01%−8,592−11.2%Reduced
DekaBank Deutsche Girozentrale80,000$1.44M0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The56,988$1.25M0.00%+16,818+41.9%Added
Legal & General Group Plc50,348$1.11M0.00%+56+0.1%Added
Prelude Capital Management, LLC49,995$1.10M0.11%+16,831+50.8%Added
Invesco Ltd.48,130$1.06M0.00%+4,695+10.8%Added
Norges Bank47,755$1.05M0.00%00.0%Unchanged
Tudor Investment Corp Et Al46,804$1.03M0.01%+2,995+6.8%Added
Franklin Resources Inc46,287$1.02M0.00%+14,680+46.4%Added
Intech Investment Management LLC46,208$1.02M0.01%+11,364+32.6%Added