Edgewise Therapeutics, Inc.
EWTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001710072
In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 6 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 214
- +20 vs. Q4 2025
- Shares held
- 118.5M
- +2.37M (+2.0%) vs. Q4 2025
- Total value
- $3.72B
- +$839.3M (+29.1%) vs. Q4 2025
- New holders
- 44
- 65 more added
- Sold out
- 24
- 66 more reduced
5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 226 | $4.82B |
| Q1 2026 | 214 | $3.72B |
| Q4 2025 | 199 | $3.02B |
| Q3 2025 | 173 | $1.82B |
| Q2 2025 | 179 | $1.56B |
| Q1 2025 | 193 | $2.32B |
| Q4 2024 | 201 | $2.64B |
| Q3 2024 | 177 | $2.71B |
| Q2 2024 | 140 | $1.83B |
| Q1 2024 | 129 | $1.67B |
| Q4 2023 | 116 | $871.4M |
| Q3 2023 | 85 | $392.2M |
| Q2 2023 | 95 | $538.8M |
| Q1 2023 | 85 | $443.1M |
| Q4 2022 | 90 | $594.1M |
| Q3 2022 | 94 | $633.5M |
| Q2 2022 | 78 | $405.7M |
| Q1 2022 | 72 | $523.5M |
| Q4 2021 | 58 | $769.4M |
| Q3 2021 | 48 | $795.8M |
| Q2 2021 | 46 | $1.03B |
| Q1 2021 | 31 | $1.48B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| OrbiMed Advisors LLC | 15,518,492 | $488.8M | 11.11% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 10,428,437 | $328.5M | 3.48% | 00.0% | Unchanged |
| Paradigm Biocapital Advisors LP | 7,365,038 | $232.0M | 4.74% | +823,828+12.6% | Added |
| Baker Bros. Advisors LP | 6,575,940 | $207.1M | 1.19% | 00.0% | Unchanged |
| BlackRock, Inc. | 6,472,991 | $203.9M | 0.00% | −157,585−2.4% | Reduced |
| Janus Henderson Group PLC | 5,915,556 | $186.3M | 0.09% | +1,348,706+29.5% | Added |
| Novo Holdings A/S | 5,350,000 | $168.5M | 13.65% | 00.0% | Unchanged |
| Driehaus Capital Management LLC | 4,477,942 | $141.1M | 1.04% | +286,749+6.8% | Added |
| Siren, L.L.C. | 4,430,263 | $139.6M | 3.87% | −99,727−2.2% | Reduced |
| Perceptive Advisors LLC | 4,423,974 | $139.4M | 2.75% | −34,000−0.8% | Reduced |
| Vanguard Capital Management LLC | 3,788,161 | $119.3M | 0.00% | +3,788,161 | New |
| Cormorant Asset Management, LP | 3,260,000 | $102.7M | 5.18% | −25,000−0.8% | Reduced |
| Braidwell LP | 2,347,583 | $73.9M | 2.47% | −2,863,248−54.9% | Reduced |
| Morgan Stanley | 2,246,028 | $70.7M | 0.00% | −664,853−22.8% | Reduced |
| Geode Capital Management, LLC | 1,789,819 | $56.4M | 0.00% | +43,597+2.5% | Added |
| State Street Corp | 1,716,823 | $54.1M | 0.00% | −5200.0% | Reduced |
| MPM Oncology Impact Management LP | 1,660,696 | $52.3M | 4.04% | +5,440+0.3% | Added |
| Integral Health Asset Management, LLC | 1,600,000 | $50.4M | 2.67% | +100,000+6.7% | Added |
| Bellevue Group AG | 1,528,518 | $48.1M | 1.15% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 1,449,915 | $45.7M | 1.85% | +539,915+59.3% | Added |
| Alliancebernstein L.P. | 1,722,169 | $42.7M | 0.01% | +685,999+66.2% | Added |
| Bank of America Corp | 1,327,360 | $41.8M | 0.00% | −147,437−10.0% | Reduced |
| UBS Group AG | 1,311,125 | $41.3M | 0.01% | −805,948−38.1% | Reduced |
| Dimensional Fund Advisors LP | 1,219,717 | $38.4M | 0.01% | +6,060+0.5% | Added |
| American Century Companies Inc | 1,147,176 | $36.1M | 0.02% | −39,291−3.3% | Reduced |
| FMR LLC | 1,017,052 | $32.0M | 0.00% | +324,097+46.8% | Added |
| First Light Asset Management, LLC | 1,001,846 | $31.6M | 2.83% | −571,855−36.3% | Reduced |
| Standard Life Aberdeen plc | 826,059 | $26.0M | 0.04% | +4,119+0.5% | Added |
| Qube Research & Technologies Ltd | 825,910 | $26.0M | 0.04% | +529,702+178.8% | Added |
| Victory Capital Management Inc | 789,043 | $24.9M | 0.02% | +42,481+5.7% | Added |
| Artisan Partners Limited Partnership | 659,067 | $20.8M | 0.03% | −45,010−6.4% | Reduced |
| Marshall Wace, LLP | 648,393 | $20.4M | 0.02% | −33,528−4.9% | Reduced |
| Goldman Sachs Group Inc | 629,820 | $19.8M | 0.00% | −88,552−12.3% | Reduced |
| Charles Schwab Investment Management Inc | 596,310 | $18.8M | 0.00% | −15,074−2.5% | Reduced |
| Northern Trust Corp | 576,556 | $18.2M | 0.00% | +16,907+3.0% | Added |
| Vanguard Portfolio Management LLC | 557,260 | $17.6M | 0.00% | +557,260 | New |
| Vanguard Fiduciary Trust Co | 521,726 | $16.4M | 0.00% | +521,726 | New |
| Opaleye Management Inc. | 500,000 | $15.8M | 2.07% | 00.0% | Unchanged |
| Candriam Luxembourg S.C.A. | 447,416 | $14.1M | 0.07% | −53,798−10.7% | Reduced |
| Citadel Advisors LLC | 429,032 | $13.5M | 0.01% | +305,935+248.5% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 404,200 | $12.7M | 0.02% | −236,200−36.9% | Reduced |
| Sofinnova Investments, Inc. | 386,498 | $12.2M | 0.61% | −51,321−11.7% | Reduced |
| Squadron Capital Management LLC | 350,000 | $11.0M | 4.41% | 00.0% | Unchanged |
| Millennium Management LLC | 342,867 | $10.8M | 0.01% | +216,431+171.2% | Added |
| Nuveen, LLC | 335,783 | $10.6M | 0.00% | +166,317+98.1% | Added |
| Parkman Healthcare Partners LLC | 322,828 | $10.2M | 1.05% | −104,862−24.5% | Reduced |
| StemPoint Capital LP | 290,864 | $9.16M | 1.76% | −70,012−19.4% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 283,312 | $8.92M | 0.02% | +11,927+4.4% | Added |
| Sio Capital Management, LLC | 268,986 | $8.47M | 1.22% | +31,505+13.3% | Added |
| Kennedy Capital Management, Inc. | 264,204 | $8.32M | 0.18% | +22,695+9.4% | Added |
| Woodline Partners LP | 224,290 | $7.07M | 0.03% | +980.0% | Added |
| Deutsche Bank AG | 221,868 | $6.99M | 0.00% | +7,099+3.3% | Added |
| Peregrine Capital Management LLC | 208,672 | $6.57M | 0.24% | +208,672 | New |
| SEB Asset Management AB | 206,512 | $6.51M | 0.03% | +206,512 | New |
| Granahan Investment Management Inc | 200,843 | $6.33M | 0.31% | −31,452−13.5% | Reduced |
| Ameriprise Financial Inc | 200,661 | $6.32M | 0.00% | −1,636−0.8% | Reduced |
| Bank of New York Mellon Corp | 192,434 | $6.06M | 0.00% | −6,180−3.1% | Reduced |
| Barclays PLC | 177,244 | $5.58M | 0.00% | −195,494−52.4% | Reduced |
| Neuberger Berman Group LLC | 168,678 | $5.31M | 0.00% | +41,542+32.7% | Added |
| Ally Bridge Group (NY) LLC | 161,000 | $5.07M | 5.04% | −34,000−17.4% | Reduced |
| Eventide Asset Management, LLC | 149,863 | $4.72M | 0.08% | −418,447−73.6% | Reduced |
| Freestone Grove Partners LP | 148,426 | $4.68M | 0.03% | +148,426 | New |
| JPMorgan Chase & Co | 147,573 | $4.47M | 0.00% | +1,535+1.1% | Added |
| Schroder Investment Management Group | 145,286 | $4.40M | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 138,399 | $4.36M | 0.00% | +62,961+83.5% | Added |
| KVP Capital Advisors, LP | 133,000 | $4.19M | 3.13% | 00.0% | Unchanged |
| Quantum Private Wealth, LLC | 116,624 | $3.67M | 1.13% | +10,600+10.0% | Added |
| UBS Asset Management Americas Inc | 114,720 | $3.61M | 0.00% | +16,657+17.0% | Added |
| Moody Aldrich Partners LLC | 114,141 | $3.60M | 0.65% | +71,007+164.6% | Added |
| DAFNA Capital Management LLC | 112,236 | $3.54M | 0.80% | −47,500−29.7% | Reduced |
| D. E. Shaw & Co., Inc. | 104,863 | $3.30M | 0.00% | −289,832−73.4% | Reduced |
| Swiss National Bank | 103,900 | $3.27M | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 99,075 | $3.12M | 0.03% | +39,749+67.0% | Added |
| HighVista Strategies LLC | 91,931 | $2.90M | 0.80% | −79,206−46.3% | Reduced |
| ADAR1 Capital Management, LLC | 90,599 | $2.85M | 0.17% | −400−0.4% | Reduced |
| New York State Common Retirement Fund | 88,937 | $2.80M | 0.00% | 00.0% | Unchanged |
| Alps Advisors Inc | 87,326 | $2.75M | 0.01% | +397+0.5% | Added |
| Rhumbline Advisers | 83,540 | $2.63M | 0.00% | −1,535−1.8% | Reduced |
| DekaBank Deutsche Girozentrale | 80,000 | $2.57M | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 73,419 | $2.31M | 0.00% | +23,027+45.7% | Added |
| Price T Rowe Associates Inc | 69,427 | $2.19M | 0.00% | +12,112+21.1% | Added |
| Nomura Asset Management International Inc. | 67,408 | $2.12M | 0.00% | +67,408 | New |
| Artia Global Partners LP | 65,500 | $2.06M | 0.47% | +65,500 | New |
| J. Goldman & Co LP | 61,421 | $1.93M | 0.09% | +61,421 | New |
| Federated Hermes, Inc. | 56,778 | $1.79M | 0.00% | −25,318−30.8% | Reduced |
| HighMark Wealth Management LLC | 53,179 | $1.68M | 0.68% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 50,848 | $1.60M | 0.00% | 00.0% | Unchanged |
| Ishara Investments LP | 49,200 | $1.55M | 1.57% | −8,800−15.2% | Reduced |
| SEI Investments Co | 49,082 | $1.55M | 0.00% | +17,832+57.1% | Added |
| Jain Global LLC | 46,401 | $1.46M | 0.02% | −67,455−59.2% | Reduced |
| Silverarc Capital Management, LLC | 42,615 | $1.34M | 0.16% | +563+1.3% | Added |
| Legal & General Group Plc | 42,537 | $1.34M | 0.00% | −10,210−19.4% | Reduced |
| Franklin Resources Inc | 41,726 | $1.31M | 0.00% | −1,419−3.3% | Reduced |
| Voya Investment Management LLC | 39,153 | $1.23M | 0.00% | −495−1.2% | Reduced |
| Caption Management, LLC | 38,675 | $1.22M | 0.06% | +38,675 | New |
| Knights of Columbus Asset Advisors LLC | 38,414 | $1.21M | 0.07% | −262−0.7% | Reduced |
| MetLife Investment Management | 38,084 | $1.20M | 0.01% | −207−0.5% | Reduced |
| Longaeva Partners L.P. | 36,931 | $1.16M | 0.06% | +36,931 | New |
| Vanguard Asset Management, Ltd | 35,744 | $1.13M | 0.00% | +35,744 | New |
| Jane Street Group, LLC | 35,578 | $1.12M | 0.00% | +35,578 | New |