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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
214
+20 vs. Q4 2025
Shares held
118.5M
+2.37M (+2.0%) vs. Q4 2025
Total value
$3.72B
+$839.3M (+29.1%) vs. Q4 2025
New holders
44
65 more added
Sold out
24
66 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 214 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2026: $3.72B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding EWTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Manufacturers Life Insurance Company, The35,450$1.12M0.00%−1,309−3.6%Reduced
State of Wisconsin Investment Board32,896$1.04M0.00%−7,101−17.8%Reduced
Algert Global LLC32,520$1.02M0.02%+32,520New
Mirae Asset Global ETFs Holdings Ltd.31,614$995.8K0.00%+245+0.8%Added
Creative Planning31,268$984.9K0.00%+6,800+27.8%Added
Handelsbanken Fonder AB31,100$980.0K0.00%00.0%Unchanged
Tudor Investment Corp Et Al29,889$941.5K0.01%+29,889New
Vanguard Global Advisers, LLC29,326$923.8K0.00%+29,326New
Wellington Management Group LLP27,409$863.4K0.00%−83,978−75.4%Reduced
Susquehanna International Group, LLP26,674$840.2K0.00%−43,522−62.0%Reduced
China Universal Asset Management Co., Ltd.25,436$801.2K0.06%+8,185+47.4%Added
Wells Fargo & Company25,244$795.2K0.00%−50,198−66.5%Reduced
BNP Paribas Arbitrage, SA23,911$753.2K0.00%+6,850+40.2%Added
LMR Partners LLP20,000$630.0K0.01%00.0%Unchanged
Raymond James Financial Inc19,678$619.9K0.00%−1,931−8.9%Reduced
Glenmede Trust Co NA19,224$605.6K0.00%+19,224New
XTX Topco Ltd19,108$601.9K0.01%−36,512−65.6%Reduced
Police & Firemen's Retirement System of New Jersey18,865$594.2K0.01%00.0%Unchanged
Citigroup Inc18,517$583.3K0.00%−204,777−91.7%Reduced
Intech Investment Management LLC18,480$582.1K0.01%−11,909−39.2%Reduced
State of New Jersey Common Pension Fund D18,091$569.9K0.00%+113+0.6%Added
Odyssean, LLC17,867$562.8K0.21%+6,114+52.0%Added
State Board of Administration of Florida Retirement System16,870$531.4K0.00%00.0%Unchanged
Skopos Labs, Inc.16,221$511.0K0.02%+16,221New
Envestnet Asset Management Inc15,730$495.5K0.00%+15,730New
AlphaCentric Advisors LLC15,615$491.9K0.49%+912+6.2%Added
Zurcher Kantonalbank (Zurich Cantonalbank)14,739$464.3K0.00%+3,474+30.8%Added
ProShare Advisors LLC14,578$459.2K0.00%−2,398−14.1%Reduced
Arizona State Retirement System14,540$458.0K0.00%−397−2.7%Reduced
Headlands Technologies LLC13,767$433.7K0.05%+13,767New
Vanguard Investments Australia, Ltd.13,686$431.1K0.00%+13,686New
Verdad Advisers, LP13,052$411.1K0.46%+13,052New
Hudson Bay Capital Management LP12,930$407.3K0.00%+12,930New
Bridgefront Capital, LLC11,809$372.0K0.09%+11,809New
Seven Fleet Capital Management LP11,701$368.6K0.12%+9,701+485.1%Added
Virtus Investment Advisers, Inc.11,544$363.6K0.10%+281+2.5%Added
Guggenheim Capital LLC11,524$363.0K0.00%+953+9.0%Added
KLP Kapitalforvaltning AS11,300$355.9K0.00%00.0%Unchanged
Prudential Financial Inc10,605$334.1K0.00%+10,605New
Persistent Asset Partners Ltd10,053$316.7K0.12%−11,151−52.6%Reduced
Elmind Capital, LP10,000$315.0K0.09%−20,000−66.7%Reduced
SFMG, LLC10,000$315.0K0.02%00.0%Unchanged
Atom Investors LP9,941$313.1K0.02%+9,941New
Connecticut Capital Management Group, LLC9,839$309.9K0.29%00.0%Unchanged
Axq Capital, LP9,513$299.7K0.04%+9,513New
First Trust Advisors LP9,129$287.6K0.00%+9,129New
Lion Point Capital, LP9,100$286.6K1.71%00.0%Unchanged
Profund Advisors LLC8,683$273.5K0.01%−3,142−26.6%Reduced
AQR Capital Management LLC8,539$269.0K0.00%−5,207−37.9%Reduced
Advisor Group Holdings, Inc.8,483$267.2K0.00%+8,075+1,979.2%Added
Fox Run Management, L.L.C.7,976$241.5K0.04%−4,384−35.5%Reduced
Pictet Asset Management Holding SA7,623$240.1K0.00%+7,623New
Quantinno Capital Management LP7,454$234.8K0.00%+7,454New
STRS Ohio6,900$217.3K0.00%+6,900New
Teacher Retirement System of Texas6,719$211.6K0.00%+6,719New
Russell Investments Group, Ltd.6,574$207.1K0.00%+80+1.2%Added
PSP Research LLC6,500$204.8K0.14%+6,500New
Brinker Capital Investments, LLC6,449$203.1K0.00%+6,449New
Quarry LP6,000$189.0K0.04%+200+3.4%Added
Royal Bank of Canada5,873$185.0K0.00%−4,295−42.2%Reduced
Ameritas Investment Partners, Inc.5,638$177.6K0.01%00.0%Unchanged
Los Angeles Capital Management LLC5,600$176.4K0.00%−2,577−31.5%Reduced
Mirae Asset Global Investments Co., Ltd.5,595$176.2K0.00%+450+8.7%Added
Tower Research Capital LLC (TRC)5,473$172.4K0.00%+3,860+239.3%Added
Caitong International Asset Management Co., Ltd4,278$134.8K0.02%+3,568+502.5%Added
SG Americas Securities, LLC3,804$120.0K0.00%−84,919−95.7%Reduced
Cygnus Capital Advisors, LLC3,427$108.0K0.07%00.0%Unchanged
US Bancorp2,973$93.7K0.00%+1,409+90.1%Added
Public Employees Retirement Association of Colorado2,849$90.0K0.00%00.0%Unchanged
Acadian Asset Management LLC2,737$86.0K0.00%+1,006+58.1%Added
GF Fund Management Co. Ltd.2,378$74.9K0.00%+299+14.4%Added
Steward Partners Investment Advisory, LLC2,354$74.2K0.00%−500−17.5%Reduced
Bessemer Group Inc2,350$74.0K0.00%00.0%Unchanged
GAMMA Investing LLC2,289$72.1K0.00%+935+69.1%Added
Simplex Trading, LLC1,832$57.7K0.00%−7,237−79.8%Reduced
Eleva Capital SAS17,460$55.0K0.02%+17,460New
Nisa Investment Advisors, LLC1,677$52.8K0.00%+515+44.3%Added
KBC Group NV1,560$49.0K0.00%+1,560New
Winthrop Capital Management, LLC1,377$43.0K0.01%00.0%Unchanged
Parallel Advisors, LLC1,032$32.5K0.00%+406+64.9%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.972$30.6K0.00%+244+33.5%Added
Kemnay Advisory Services Inc.756$23.8K0.00%+756New
Rockefeller Capital Management L.P.732$23.1K0.00%+550+302.2%Added
Farther Finance Advisors, LLC645$21.4K0.00%−14−2.1%Reduced
Clear Street Markets LLC678$21.4K0.01%+678New
Centiva Capital, LP539$17.0K0.00%−11,961−95.7%Reduced
Sterling Capital Management LLC438$13.8K0.00%−10−2.2%Reduced
Signaturefd, LLC363$11.4K0.00%00.0%Unchanged
CWM, LLC351$11.1K0.00%+72+25.8%Added
Massmutual Trust Co FSB294$9.26K0.00%00.0%Unchanged
Optiver Holding B.V.261$8.22K0.00%+100+62.1%Added
Eastern Bank223$7.03K0.00%00.0%Unchanged
Aster Capital Management (DIFC) Ltd310$6.82K0.00%+158+103.9%Added
SBI Securities Co., Ltd.206$6.49K0.00%−1−0.5%Reduced
Larson Financial Group LLC176$5.54K0.00%−49−21.8%Reduced
EverSource Wealth Advisors, LLC175$5.51K0.00%+19+12.2%Added
The PNC Financial Services Group, Inc.172$5.42K0.00%+97+129.3%Added
Fortitude Family Office, LLC160$5.04K0.00%00.0%Unchanged
Smartleaf Asset Management LLC162$4.91K0.00%−11−6.4%Reduced
Advisory Services Network, LLC151$4.77K0.00%+151New