| Aug 20, 20264:10 PM ET | Aug 18, 2026 | Tanini AnnitaCorp. Controller & VP, Finance | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.22K | $10.29 | −$12.59K | 45.14K | −2.6% | SEC↗ |
| Aug 20, 20264:10 PM ET | Aug 18, 2026 | Lerner Lorena RaquelChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.57K | $10.29 | −$36.71K | 27.56K | −11.5% | SEC↗ |
| Aug 20, 20264:10 PM ET | Aug 18, 2026 | Cho EstherChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.49K | $10.29 | −$46.15K | 35.77K | −11.1% | SEC↗ |
| Aug 20, 20264:10 PM ET | Aug 18, 2026 | Newton Charles W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −551 | $10.30 | −$5.68K | 12.11K | −4.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 19, 20264:10 PM ET | Aug 17, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1K | $10.27 | +$10.27K | 19.59K | +5.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 17, 20264:10 PM ET | Jul 15, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1K | $10.61 | +$10.61K | 18.59K | +5.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 17, 2026 | Jun 15, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1K | $10.19 | +$10.19K | 17.59K | +6.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 15, 2026 | Jun 11, 2026 | Newton Charles W.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −550 | $10.04 | −$5.52K | 12.67K | −4.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 8, 2026 | Jun 4, 2026 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.63K | $10.73 | −$28.17K | 10.96K | −19.3% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 8, 2026 | Jun 4, 2026 | Farzan NimaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.63K | $10.73 | −$28.17K | 9.77K | −21.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2026 | Jun 4, 2026 | Seth AlpnaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.63K | $10.72 | −$28.14K | 9.77K | −21.2% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 19, 2026 | May 15, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1K | $10.58 | +$10.58K | 9.45K | +11.8% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2026 | Apr 15, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1K | $11.70 | +$11.7K | 8.45K | +13.4% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 | Mar 9, 2026 | BIENAIME JEAN JACQUESDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +2K | $11.21 | +$22.42K | 7.45K | +36.7% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 20, 2026 | Feb 18, 2026 | Cho EstherSVP, General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.75K | $16.35 | −$77.58K | 39.76K | −10.7% | SEC↗ |
| Feb 20, 2026 | Feb 18, 2026 | Lerner Lorena RaquelChief Science Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.87K | $16.35 | −$63.32K | 31.13K | −11.1% | SEC↗ |
| Feb 20, 2026 | Feb 19, 2026 | Seehra JasbirCHIEF EXECUTIVE OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.02K | $16.17 | −$113.43K | 385.71K | −1.8% | SEC↗ |
| Feb 20, 2026 | Feb 18, 2026 | Regnante KeithCHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.74K | $16.35 | −$77.48K | 39.26K | −10.8% | SEC↗ |
| Oct 17, 20255:53 PM ET | Oct 15, 2025 | Kariv Tomer and 7 othersDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock, $0.0001 par value per share | −4.79M | $17.75 | −$84.98M | 0 | −100.0% | SEC↗ |
| Oct 15, 20251:24 PM ET | Oct 15, 2025 | ADAR1 Partners, LP and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.39M | $17.75 | −$95.66M | 0 | −100.0% | SEC↗ |
| Apr 11, 20259:57 PM ET | Apr 9, 2025 | ADAR1 Partners, LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +934.26K | $10.1305 | +$9.46M | 4.39M | +27.0% | SEC↗ |
| Jan 24, 2025AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. | Jan 4, 2024 | Regnante KeithCHIEF FINANCIAL OFFICER | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −40K | $45.29 | −$1.81M | 0 | −100.0% | SEC↗ |
| Aug 15, 20245:01 PM ET | Aug 13, 2024 | ORBIMED ADVISORS LLC and 2 othersDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −250K | $44.01 | −$11M | 119.52K | −67.7% | SEC↗ |
| Aug 15, 2024 | Aug 13, 2024 | GORDON CARL LDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −250K | $44.01 | −$11M | 119.52K | −67.7% | SEC↗ |
| Jun 12, 2023 | Jun 8 – Jun 9, 2023 | Regnante KeithChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −40K | $46.606 | −$1.86M | 0 | −100.0% | SEC↗10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 20, 2023 | Apr 13, 2020 | Knowles JuliusDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +1.19K | $20.98 | +$24.99K | 1.19K | New position | SEC↗ |
| Jul 19, 20224:40 PM ET | Jul 15, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −46.03K | $30.00 | −$1.38M | 95.1K | −32.6% | SEC↗ |
| Jul 15, 20224:40 PM ET | Jul 13, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.92K | $30.00 | −$57.48K | 95.1K | −2.0% | SEC↗ |
| May 13, 20224:37 PM ET | May 11, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.3K | $41.8962 | −$222.05K | 85.7K | −5.8% | SEC↗ |
| Apr 13, 20224:36 PM ET | Apr 11, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.3K | $62.7744 | −$332.7K | 85.7K | −5.8% | SEC↗ |
| Apr 8, 2022 | Apr 6, 2022 | Rovaldi ChristopherChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.73K | $65.00 | −$112.32K | 0 | −100.0% | SEC↗ |
| Apr 6, 20224:49 PM ET | Apr 4, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.95K | $60.00 | −$477K | 85.7K | −8.5% | SEC↗ |
| Apr 5, 2022 | Apr 1, 2022 | Rovaldi ChristopherChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −864 | $57.4943 | −$49.68K | 0 | −100.0% | SEC↗ |
| Mar 15, 20224:37 PM ET | Mar 11, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.65K | $53.3769 | −$141.45K | 85.7K | −3.0% | SEC↗ |
| Feb 15, 20224:26 PM ET | Feb 11, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.65K | $52.0622 | −$137.96K | 85.7K | −3.0% | SEC↗ |
| Jan 13, 20224:39 PM ET | Jan 11, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.65K | $53.7537 | −$142.45K | 85.7K | −3.0% | SEC↗ |
| Jan 7, 20224:35 PM ET | Jan 5, 2022 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.65K | $60.00 | −$159K | 85.7K | −3.0% | SEC↗ |
| Jan 5, 2022 | Jan 3 – Jan 5, 2022 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −47.65K | $57.8396 | −$2.76M | 232.73K | −17.0% | SEC↗ |
| Dec 15, 20214:48 PM ET | Dec 13 – Dec 15, 2021 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.65K | $50.3993 | −$133.56K | 85.7K | −3.0% | SEC↗ |
| Dec 3, 2021 | Dec 1 – Dec 2, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −47.65K | $54.0886 | −$2.58M | 251.54K | −15.9% | SEC↗ |
| Nov 12, 20214:40 PM ET | Nov 10 – Nov 11, 2021 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −21.2K | $59.9084 | −$1.27M | 85.7K | −19.8% | SEC↗ |
| Nov 5, 20215:06 PM ET | Nov 4, 2021 | Lachey JenniferChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −10.6K | $50.00 | −$530K | 85.7K | −11.0% | SEC↗ |
| Nov 3, 2021 | Nov 1 – Nov 3, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −47.65K | $42.1215 | −$2.01M | 270.35K | −15.0% | SEC↗ |
| Oct 21, 2021 | Oct 19 – Oct 20, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −8.6K | $38.1997 | −$328.44K | 289.16K | −2.9% | SEC↗ |
| Oct 18, 2021 | Oct 14 – Oct 18, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −26.37K | $38.5578 | −$1.02M | 292.55K | −8.3% | SEC↗ |
| Oct 5, 2021 | Oct 1 – Oct 5, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −12.69K | $40.1037 | −$508.75K | 302.96K | −4.0% | SEC↗ |
| Sep 29, 2021 | Sep 27, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −95.3K | $41.1744 | −$3.92M | 307.97K | −23.6% | SEC↗ |
| Jul 6, 2021 | Jul 1 – Jul 2, 2021 | Knowles JuliusDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −47.65K | $41.3068 | −$1.97M | 345.59K | −12.1% | SEC↗ |
