| Apr 2, 2026 (view filing) | Apr 1 | 1 day | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −942 | $52.75 | −$49.7K | −0.9%105.7K after | |
| Mar 17, 2026 (view filing) | Mar 16 | 1 day | Burroughs Amy L.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.6K | $46.71 | −$681.2K | −4.8%289.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 18, 2026 (view filing) | Feb 17 | 1 day | Burroughs Amy L.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.6K | $39.20 | −$571.6K | −4.8%289.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 16, 2026 (view filing) | Jan 15 | 1 day | Burroughs Amy L.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −68.7K | $37.08 | −$2.55M | −19.2%289.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2026 (view filing) | Jan 2 | 4 days | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.16K | $38.57 | −$44.6K | −2.2%50.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 6, 2026 (view filing) | Jan 5 | 1 day | Burroughs Amy L.Chief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −71.3K | $38.10 | −$2.72M | −33.9%139.0K after | |
| Nov 5, 2025 (view filing) | Nov 4 | 1 day | Quigley Jill M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.5K | $18.00 | −$441.4K | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 2, 2025 (view filing) | Oct 1 | 1 day | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −944 | $7.85 | −$7.41K | −1.8%51.5K after | |
| Jul 3, 2025 (view filing) | Jul 1 | 2 days | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −853 | $4.27 | −$3.64K | −1.6%52.5K after | |
| Jun 30, 2025 (view filing) | Jun 27 | 3 days | Gengos AndrewChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.0K | $3.93 | +$39.3K | +66.7%25.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 25, 2025 (view filing) | Jun 25 | Same day | Burroughs Amy L.Chief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +23.3K | $3.87 | +$90.2K | +98.1%47.1K after | |
| Jun 16, 2025 (view filing) | Jun 13-16 | 3 days | Gengos AndrewChief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +15.0K | $3.81 | +$57.1K | New position15.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 2, 2025 (view filing) | Apr 1 | 1 day | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −952 | $2.49 | −$2.37K | −1.8%53.3K after | |
| Feb 3, 2025 (view filing) | Nov 30, 2024 | 65 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Jung Melita SunChief Business Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.25K | $5.11 | +$11.5K | New position2.25K after | |
| Feb 3, 2025 (view filing) | Nov 30, 2024 | 65 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Burroughs Amy L.Chief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +510 | $5.11 | +$2.61K | +2.7%19.6K after | |
| Jan 6, 2025 (view filing) | Jan 2 | 4 days | Kuriakose EmilChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.48K | $5.71 | −$25.6K | −7.6%54.3K after | |
| Jan 6, 2025 (view filing) | Jan 2-6 | 4 days | Vignola Mark J.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.2K | $5.76 | −$99.0K | −18.7%74.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2025 (view filing) | Jan 2-6 | 4 days | Quigley Jill M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $5.76 | −$86.4K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 9, 2024 (view filing) | Dec 5 | 4 days | Burroughs Amy L.Chief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +15.4K | $7.15 | +$110.5K | +423.4%19.1K after | |
| Sep 17, 2024 (view filing) | Sep 12 | 5 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Lu HongboDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +476.2K | $10.50 | +$5.00M | New position476.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 12, 2024 (view filing) | Sep 10 | 2 days | Vignola Mark J.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $11.00 | −$110.0K | −9.8%91.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 11, 2024 (view filing) | Sep 9 | 2 days | Quigley Jill M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.2K | $10.00 | −$172.3K | −53.5%15.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 5, 2024 (view filing) | Aug 1-2 | 4 days | Quigley Jill M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $7.57 | −$113.6K | −50.0%15.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 17, 2024 (view filing)8:48 PM ET | Jul 15-16 | 2 days | OrbiMed Advisors LLC and 4 othersDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −56.2K | $10.00 | −$561.6K | −6.9%755.6K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Jul 17, 2024 (view filing) | Jul 15-16 | 2 days | Quigley Jill M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.8K | $10.00 | −$147.7K | −33.0%30.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 17, 2024 (view filing) | Jul 15-16 | 2 days | Gordon Carl LDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −56.2K | $10.00 | −$561.6K | −6.9%755.6K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 4, 2024 (view filing) | May 31 | 4 days | Yoon Seokho BryanCOO and General Counsel | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +4.79K | $4.44 | +$21.3K | +5.5%91.9K after | |
| Jun 4, 2024 (view filing) | May 31 | 4 days | Vignola Mark J.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +4.79K | $4.44 | +$21.3K | +5.5%91.9K after | |
| Apr 3, 2024 (view filing)8:47 PM ET | Apr 1-3 | 2 days | Vivo Capital Fund VIII, L.P. and 4 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −420.7K | $6.65 | −$2.80M | −61.0%268.6K after | 9 lotsThis row combines 9 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 4, 2023 (view filing) | Nov 30 | 4 days | Yoon Seokho BryanCOO and General Counsel | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +743 | $3.78 | +$2.81K | +4.2%18.4K after | |
| Dec 4, 2023 (view filing) | Nov 30 | 4 days | Vignola Mark J.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +743 | $3.78 | +$2.81K | +4.2%18.4K after | |
| Jun 2, 2023 (view filing) | May 31 | 2 days | Vignola Mark J.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.0K | $1.41 | +$14.1K | +130.5%17.7K after | |
| Jun 2, 2023 (view filing) | May 31 | 2 days | Yoon Seokho BryanCOO and General Counsel | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.0K | $1.41 | +$14.1K | +130.5%17.7K after | |
| Jun 2, 2023 (view filing) | May 31 | 2 days | Sundaram Senthil VelChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.11K | $1.41 | +$2.98K | +27.6%9.77K after | |
| Feb 3, 2023 (view filing) | Nov 30, 2022 | 65 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Yoon Seokho BryanCOO and General Counsel | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3 | $1.41 | +$4.23 | 0.0%7.66K after | |
| Feb 3, 2023 (view filing) | Nov 30, 2022 | 65 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Vignola Mark J.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3 | $1.41 | +$4.23 | 0.0%7.66K after | |
| Feb 3, 2023 (view filing) | Nov 30, 2022 | 65 daysLateFiled more than 2 business days after the trade (the Form 4 deadline). A few cases, such as trades a broker makes under a 10b5-1 plan, have a longer deadline, so this flag comes from the dates alone and does not mean a rule was broken. | Sundaram Senthil VelChief Executive Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3 | $1.41 | +$4.23 | 0.0%7.66K after | |
| Dec 28, 2022 (view filing)5:57 PM ET | Dec 23 | 5 days | OrbiMed Advisors LLC and 4 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +137.9K | $7.25 | +$1.00M | +2.9%4.88M after | Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Dec 28, 2022 (view filing) | Dec 23 | 5 days | Gordon Carl LDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +137.9K | $7.25 | +$1.00M | +2.9%4.88M after | |
| Dec 23, 2022 (view filing)5:48 PM ET | Dec 23 | Same day | Vivo Capital Fund VIII, L.P. and 4 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +758.6K | $7.25 | +$5.50M | +21.2%4.34M after | Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Dec 23, 2022 (view filing) | Dec 23 | Same day | Lu HongboDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +758.6K | $7.25 | +$5.50M | +21.2%4.34M after | |
| Nov 28, 2022 (view filing)4:56 PM ET | Nov 23 | 5 days | LAV Biosciences Fund V, L.P. and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50M | $5.50 | −$8.25M | −73.9%529.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 8, 2022 (view filing)8:00 PM ET | Sep 7 | 1 day | Vivo Capital Fund VIII, L.P. and 4 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +600.0K | $3.60 | +$2.16M | +20.1%3.58M after | Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Sep 8, 2022 (view filing) | Sep 7 | 1 day | Lu HongboDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +600.0K | $3.60 | +$2.16M | +20.1%3.58M after | |
| Aug 18, 2022 (view filing)5:00 PM ET | Aug 16 | 2 days | OrbiMed Advisors LLC and 4 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3.69M | $2.42 | +$8.93M | New position762.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Aug 18, 2022 (view filing)5:00 PM ET | Aug 16 | 2 days | OrbiMed Advisors LLC and 4 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +310.0K | – | – | –64.0K after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Aug 18, 2022 (view filing) | Aug 16 | 2 days | Gordon Carl LDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3.69M | $2.42 | +$8.93M | New position762.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 18, 2022 (view filing) | Aug 16 | 2 days | Gordon Carl LDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +310.0K | – | – | –64.0K after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity.3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 16, 2022 (view filing)8:44 PM ET | Aug 12-16 | 4 days | Vivo Capital Fund VIII, L.P. and 4 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +2.62M | $2.66 | +$6.98M | +734.4%2.98M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Aug 16, 2022 (view filing)8:44 PM ET | Aug 16 | Same day | Vivo Capital Fund VIII, L.P. and 4 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.50M | $2.42 | +$3.63M | –1.50M after | DerivativeA trade in a derivative security (option, warrant, restricted stock unit and so on). The value is the derivative's own price times the quantity. |
