| Apr 13, 20265:20 PM ET | Feb 18 – Feb 20, 2026 | RA Capital Healthcare Fund LP and 3 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +223.6K | $7.1734 | +$1.6M | 1.18M | +23.3% | SEC↗ |
| Apr 9, 20265:38 PM ET | Apr 7 – Apr 8, 2026 | ORBIMED ADVISORS LLC and 7 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −104.66K | $6.4481 | −$674.85K | 0 | −100.0% | SEC↗ |
| Oct 10, 20258:06 PM ET | Oct 8, 2025 | ORBIMED ADVISORS LLC and 7 others10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5M | $1.00 | +$5M | 4.49M | New position | SEC↗ |
| Jun 7, 2024 | Jun 5, 2024 | Kauffman MichaelDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.9K | $1.43 | −$8.44K | 5.9K | −50.0% | SEC↗ |
| Jan 26, 20247:14 PM ET | Jan 25, 2024 | ORBIMED ADVISORS LLC and 7 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +3.13M | $2.40 | +$7.5M | 1.26M | New position | SEC↗ |
| Jan 26, 2024 | Jan 25, 2024 | GORDON CARL LDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +3.13M | $2.40 | +$7.5M | 1.26M | New position | SEC↗ |
| Oct 2, 2023 | Sep 28, 2023 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.5K | $1.42 | −$7.81K | 37.97K | −12.7% | SEC↗ |
| Oct 2, 2023 | Sep 28, 2023 | Schor ChenPresident & CEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5.5K | $1.42 | +$7.81K | 182.47K | +3.1% | SEC↗ |
| Oct 2, 2023 | Sep 29, 2023 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −5.5K | $1.36 | −$7.48K | 176.97K | −3.0% | SEC↗ |
| Oct 2, 2023 | Oct 2, 2023 | Schor ChenPresident & CEO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5.5K | $1.33 | +$7.32K | 43.47K | +14.5% | SEC↗ |
| Jun 30, 2023 | Jun 30, 2023 | DUBIN STEVEDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +5K | $2.40 | +$12K | 10.9K | +84.7% | SEC↗ |
| Jun 29, 20234:46 PM ET | Jun 27, 2023 | ORBIMED ADVISORS LLC and 8 othersDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +875K | $2.09 | +$1.83M | 748.05K | New position | SEC↗ |
| Jun 29, 2023 | Jun 27, 2023 | GORDON CARL LDirector, 10% Owner | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +875K | $2.09 | +$1.83M | 748.05K | New position | SEC↗ |
| Feb 17, 2023 | Feb 15, 2023 | Healey DonChief Technology Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.53K | $7.57 | −$34.31K | 66.57K | −6.4% | SEC↗ |
| Feb 14, 2023 | Feb 10, 2023 | Healey DonChief Technology Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −10.47K | $7.98 | −$83.53K | 71.1K | −12.8% | SEC↗ |
| Nov 15, 2022 | Nov 10, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.97K | $21.00 | −$146.31K | 28.21K | −19.8% | SEC↗ |
| Nov 15, 2022 | Nov 10, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −9.96K | $21.03 | −$209.35K | 91.47K | −9.8% | SEC↗ |
| Nov 15, 2022 | Nov 10, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −30K | $20.06 | −$601.8K | 53.42K | −36.0% | SEC↗ |
| Nov 9, 2022 | Nov 7, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −30K | $19.05 | −$571.5K | 83.42K | −26.4% | SEC↗ |
| Nov 4, 2022 | Nov 2 – Nov 3, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −25.31K | $18.0392 | −$456.63K | 113.42K | −18.2% | SEC↗ |
| Oct 21, 2022 | Oct 19, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −8.07K | $16.27 | −$131.25K | 35.18K | −18.7% | SEC↗ |
| Oct 14, 2022 | Oct 12, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.65K | $15.40 | −$25.35K | 51.18K | −3.1% | SEC↗ |
| Sep 16, 2022 | Sep 14, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −952 | $18.00 | −$17.14K | 138.74K | −0.7% | SEC↗ |
| Sep 13, 20224:59 PM ET | Sep 9 – Sep 13, 2022 | Schor ChenPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −78.41K | $16.7987 | −$1.32M | 139.69K | −36.0% | SEC↗ |
| Aug 5, 2022 | Aug 3, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.97K | $18.00 | −$125.42K | 38.97K | −15.2% | SEC↗ |
| Aug 3, 2022 | Aug 1, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.97K | $16.64 | −$115.95K | 45.94K | −13.2% | SEC↗ |
| Jul 7, 2022 | Jul 5, 2022 | Aftab BlakeChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1.36K | $14.50 | −$19.76K | 52.9K | −2.5% | SEC↗ |
| Apr 5, 2022 | Apr 1 – Apr 4, 2022 | Galimi FrancescoSVP & Chief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −15.6K | $21.00 | −$327.6K | 59.92K | −20.7% | SEC↗ |
| Mar 11, 2022 | Mar 9, 2022 | Jakobovits AyaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4K | $14.00 | −$56K | 356.35K | −1.1% | SEC↗ |
| Feb 17, 2022 | Feb 16, 2022 | Jakobovits AyaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4K | $14.83 | −$59.32K | 358.35K | −1.1% | SEC↗ |
| Feb 14, 2022 | Jan 3 – Feb 9, 2022 | Jakobovits AyaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −24K | $16.5058 | −$396.14K | 360.35K | −6.2% | SEC↗ |
| Dec 13, 2021AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing. | Dec 8, 2021 | Sinclair AndrewDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in.Common Stock | +500K | $14.00 | +$7M | 2.12M | +31.0% | SEC↗ |
