| Oct 27, 20255:19 PM ET | Oct 23, 2025 | ORBIMED ADVISORS LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −1M | $1.52 | −$1.52M | 4.98M | −16.7% | SEC↗ |
| Sep 12, 20255:09 PM ET | Sep 10, 2025 | ORBIMED ADVISORS LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −500K | $1.80 | −$900K | 5.98M | −7.7% | SEC↗ |
| Jul 3, 2025 | Jul 1, 2025 | Ticktin RobertGeneral Counsel & COO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −23.15K | $1.06 | −$24.54K | 98.7K | −19.0% | SEC↗ |
| Jul 3, 2025 | Jul 1, 2025 | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −33.07K | $1.06 | −$35.05K | 89.96K | −26.9% | SEC↗ |
| Jul 3, 2025 | Jul 1, 2025 | Carulli MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −28.25K | $1.06 | −$29.94K | 60.15K | −32.0% | SEC↗ |
| Jul 3, 2025 | Jul 1, 2025 | Mack David HenryPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −58.41K | $1.06 | −$61.92K | 536.13K | −9.8% | SEC↗ |
| Sep 12, 2024 | Sep 11, 2024 | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.22K | $1.50 | −$10.83K | 118.28K | −5.8% | SEC↗ |
| Sep 12, 2024 | Sep 11, 2024 | Carulli MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.89K | $1.50 | −$4.34K | 88.4K | −3.2% | SEC↗ |
| Nov 24, 20234:38 PM ET | Nov 22, 2023 | ORBIMED ADVISORS LLC and 2 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −87.79K | $2.23 | −$195.76K | 0 | −100.0% | SEC↗ |
| Sep 18, 2023 | Sep 15, 2023 | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.1K | $6.62 | −$27.17K | 29.95K | −12.1% | SEC↗ |
| Sep 18, 2023 | Sep 15, 2023 | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −6.29K | $6.62 | −$41.65K | 45.91K | −12.1% | SEC↗ |
| May 31, 20224:36 PM ET | May 26, 2022 | ORBIMED ADVISORS LLC and 2 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −26.25K | $15.93 | −$418.21K | 87.79K | −23.0% | SEC↗ |
| Mar 31, 20225:30 PM ET | Mar 29 – Mar 31, 2022 | ORBIMED ADVISORS LLC and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −474.5K | $21.6321 | −$10.26M | 0 | −100.0% | SEC↗ |
| Oct 8, 2021 | Oct 6, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −800 | $30.15 | −$24.12K | 1.1M | −0.1% | SEC↗ |
| Oct 4, 2021 | Sep 30 – Oct 4, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −14.62K | $30.0856 | −$439.82K | 1.1M | −1.3% | SEC↗ |
| Sep 29, 2021 | Sep 27 – Sep 29, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −7.46K | $30.0564 | −$224.25K | 1.12M | −0.7% | SEC↗ |
| Sep 24, 2021 | Sep 22, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −100 | $30.00 | −$3K | 1.12M | 0.0% | SEC↗ |
| Sep 23, 2021 | Sep 22, 2021 | LEVINE ARNOLD JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.5K | $30.00 | −$105K | 409.84K | −0.8% | SEC↗ |
| Sep 21, 2021 | Sep 17, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −711 | $30.03 | −$21.35K | 1.12M | −0.1% | SEC↗ |
| Sep 13, 2021 | Sep 9 – Sep 13, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −70.83K | $30.4118 | −$2.15M | 1.12M | −5.9% | SEC↗ |
| Sep 10, 2021 | Sep 9, 2021 | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −100 | $30.25 | −$3.03K | 0 | −100.0% | SEC↗ |
| Sep 8, 2021 | Sep 7, 2021 | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.9K | $30.25 | −$117.98K | 0 | −100.0% | SEC↗ |
| Sep 2, 2021 | Aug 31 – Sep 2, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −46.91K | $30.2453 | −$1.42M | 1.2M | −3.8% | SEC↗ |
| Aug 30, 2021 | Aug 26 – Aug 30, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −58.83K | $30.4458 | −$1.79M | 1.24M | −4.5% | SEC↗ |
| Aug 25, 2021 | Aug 23 – Aug 25, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −51.85K | $30.8741 | −$1.6M | 1.59M | −3.2% | SEC↗ |
| Aug 24, 2021 | Aug 23, 2021 | LEVINE ARNOLD JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.5K | $29.50 | −$103.25K | 413.34K | −0.8% | SEC↗ |
| Aug 20, 2021 | Aug 18 – Aug 19, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −30.66K | $33.0459 | −$1.01M | 1.64M | −1.8% | SEC↗ |
| Aug 18, 2021 | Aug 17, 2021 | Jalota DeepikaSVP, Regulatory Affairs and QA | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −2.9K | $33.78 | −$97.83K | 0 | −100.0% | SEC↗ |
| Aug 17, 2021 | Aug 13 – Aug 17, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −80.49K | $33.8879 | −$2.73M | 1.67M | −4.6% | SEC↗ |
| Aug 12, 2021 | Aug 10 – Aug 12, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −68.48K | $34.3603 | −$2.35M | 1.75M | −3.8% | SEC↗ |
| Aug 10, 2021 | Aug 9, 2021 | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.47K | $34.0418 | −$152.2K | 0 | −100.0% | SEC↗ |
| Aug 9, 2021 | Aug 5 – Aug 9, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −77.69K | $36.2318 | −$2.81M | 1.82M | −4.1% | SEC↗ |
| Aug 4, 2021 | Aug 2 – Aug 4, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −96.14K | $35.0538 | −$3.37M | 1.9M | −4.8% | SEC↗ |
| Aug 4, 2021 | Aug 3, 2021 | Kung WinstonCOO, CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.5K | $33.82 | −$152.19K | 1.6K | −73.8% | SEC↗ |
| Jul 30, 2021 | Jul 28 – Jul 29, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −11.02K | $35.7537 | −$394.15K | 1.99M | −0.6% | SEC↗ |
| Jul 27, 2021 | Jul 23 – Jul 27, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −17.36K | $35.9127 | −$623.52K | 2M | −0.9% | SEC↗ |
| Jul 23, 2021 | Jul 21 – Jul 22, 2021 | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −18.87K | $35.8178 | −$675.95K | 2.02M | −0.9% | SEC↗ |
| Jul 22, 2021 | Jul 20, 2021 | LEVINE ARNOLD JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −3.5K | $35.12 | −$122.92K | 416.84K | −0.8% | SEC↗ |
| Jul 22, 2021 | Jul 20 – Jul 21, 2021 | Mack David HenryPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −27.8K | $35.7515 | −$993.75K | 12.47K | −69.0% | SEC↗ |
| Jul 8, 2021 | Jul 8, 2021 | Kung WinstonCOO, CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4.5K | $33.75 | −$151.88K | 1.6K | −73.8% | SEC↗ |
| Jul 8, 2021 | Jul 7, 2021 | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase.Common Stock | −4K | $32.3039 | −$129.22K | 0 | −100.0% | SEC↗ |
