| Jul 8, 2021 (view filing) | Jul 7 | 1 day | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.00K | $32.30 | −$129.2K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 8, 2021 (view filing) | Jul 8 | Same day | Kung WinstonCOO, CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $33.75 | −$151.9K | −73.8%1.60K after | |
| Jul 22, 2021 (view filing) | Jul 20-21 | 2 days | Mack David HenryPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −27.8K | $35.75 | −$993.7K | −69.0%12.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 22, 2021 (view filing) | Jul 20 | 2 days | Levine Arnold JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.50K | $35.12 | −$122.9K | −0.8%416.8K after | |
| Jul 23, 2021 (view filing) | Jul 21-22 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −18.9K | $35.82 | −$676.0K | −0.9%2.02M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 27, 2021 (view filing) | Jul 23-27 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.4K | $35.91 | −$623.5K | −0.9%2.00M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 30, 2021 (view filing) | Jul 28-29 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.0K | $35.75 | −$394.1K | −0.6%1.99M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 4, 2021 (view filing) | Aug 3 | 1 day | Kung WinstonCOO, CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $33.82 | −$152.2K | −73.8%1.60K after | |
| Aug 4, 2021 (view filing) | Aug 2-4 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −96.1K | $35.05 | −$3.37M | −4.8%1.90M after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 9, 2021 (view filing) | Aug 5-9 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −77.7K | $36.23 | −$2.81M | −4.1%1.82M after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 10, 2021 (view filing) | Aug 9 | 1 day | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.47K | $34.04 | −$152.2K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 12, 2021 (view filing) | Aug 10-12 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −68.5K | $34.36 | −$2.35M | −3.8%1.75M after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2021 (view filing) | Aug 13-17 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −80.5K | $33.89 | −$2.73M | −4.6%1.67M after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 18, 2021 (view filing) | Aug 17 | 1 day | Jalota DeepikaSVP, Regulatory Affairs and QA | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.90K | $33.78 | −$97.8K | −100.0%0 after | |
| Aug 20, 2021 (view filing) | Aug 18-19 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.7K | $33.05 | −$1.01M | −1.8%1.64M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 24, 2021 (view filing) | Aug 23 | 1 day | Levine Arnold JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.50K | $29.50 | −$103.3K | −0.8%413.3K after | |
| Aug 25, 2021 (view filing) | Aug 23-25 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −51.9K | $30.87 | −$1.60M | −3.2%1.59M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 30, 2021 (view filing) | Aug 26-30 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −58.8K | $30.45 | −$1.79M | −4.5%1.24M after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 2, 2021 (view filing) | Aug 31-Sep 2 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −46.9K | $30.25 | −$1.42M | −3.8%1.20M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 8, 2021 (view filing) | Sep 7 | 1 day | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.90K | $30.25 | −$118.0K | −100.0%0 after | |
| Sep 10, 2021 (view filing) | Sep 9 | 1 day | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100 | $30.25 | −$3.02K | −100.0%0 after | |
| Sep 13, 2021 (view filing) | Sep 9-13 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −70.8K | $30.41 | −$2.15M | −5.9%1.12M after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 21, 2021 (view filing) | Sep 17 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −711 | $30.03 | −$21.4K | −0.1%1.12M after | |
| Sep 23, 2021 (view filing) | Sep 22 | 1 day | Levine Arnold JDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.50K | $30.00 | −$105.0K | −0.8%409.8K after | |
| Sep 24, 2021 (view filing) | Sep 22 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −100 | $30.00 | −$3.00K | 0.0%1.12M after | |
| Sep 29, 2021 (view filing) | Sep 27-29 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.46K | $30.06 | −$224.3K | −0.7%1.12M after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 4, 2021 (view filing) | Sep 30-Oct 4 | 4 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.6K | $30.09 | −$439.8K | −1.3%1.10M after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 8, 2021 (view filing) | Oct 6 | 2 days | Schroeder ThiloDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −800 | $30.15 | −$24.1K | −0.1%1.10M after | |
| Mar 31, 2022 (view filing)5:30 PM ET | Mar 29-31 | 2 days | OrbiMed Advisors LLC and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −474.5K | $21.63 | −$10.3M | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| May 31, 2022 (view filing)4:36 PM ET | May 26 | 5 days | OrbiMed Advisors LLC and 2 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.3K | $15.93 | −$418.2K | −23.0%87.8K after | |
| Sep 18, 2023 (view filing) | Sep 15 | 3 days | Alland LeilaChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.29K | $6.62 | −$41.6K | −12.1%45.9K after | |
| Sep 18, 2023 (view filing) | Sep 15 | 3 days | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.10K | $6.62 | −$27.2K | −12.1%29.9K after | |
| Nov 24, 2023 (view filing)4:38 PM ET | Nov 22 | 2 days | OrbiMed Advisors LLC and 2 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −87.8K | $2.23 | −$195.8K | −100.0%0 after | |
| Sep 12, 2024 (view filing) | Sep 11 | 1 day | Carulli MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.89K | $1.50 | −$4.34K | −3.2%88.4K after | |
| Sep 12, 2024 (view filing) | Sep 11 | 1 day | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.22K | $1.50 | −$10.8K | −5.8%118.3K after | |
| Jul 3, 2025 (view filing) | Jul 1 | 2 days | Mack David HenryPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −58.4K | $1.06 | −$61.9K | −9.8%536.1K after | |
| Jul 3, 2025 (view filing) | Jul 1 | 2 days | Carulli MichaelChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −28.2K | $1.06 | −$29.9K | −32.0%60.1K after | |
| Jul 3, 2025 (view filing) | Jul 1 | 2 days | Jalota DeepikaChief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −33.1K | $1.06 | −$35.0K | −26.9%90.0K after | |
| Jul 3, 2025 (view filing) | Jul 1 | 2 days | Ticktin RobertGeneral Counsel & COO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −23.2K | $1.06 | −$24.5K | −19.0%98.7K after | |
| Sep 12, 2025 (view filing)5:09 PM ET | Sep 10 | 2 days | OrbiMed Advisors LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −500.0K | $1.80 | −$900.0K | −7.7%5.98M after | |
| Oct 27, 2025 (view filing)5:19 PM ET | Oct 23 | 4 days | OrbiMed Advisors LLC and 1 other10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00M | $1.52 | −$1.52M | −16.7%4.98M after | |
