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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Prelude Therapeutics Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
62
−8 vs. Q3 2024
Shares held
32.2M
−3.58M (−10.0%) vs. Q3 2024
Total value
$41.0M
−$33.0M (−44.6%) vs. Q3 2024
New holders
8
26 more added
Sold out
16
12 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 62 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ4 2024: $41.0M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q3 2024.

Institutions holding PRLD in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC10,909,256$13.9M0.29%00.0%Unchanged
Baker Bros. Advisors LP10,123,824$12.9M0.14%00.0%Unchanged
Boxer Capital Management, LLC1,708,187$2.18M0.19%+1,708,187New
BlackRock, Inc.1,069,773$1.36M0.00%+11,457+1.1%Added
Price T Rowe Associates Inc1,029,199$1.31M0.00%−68,400−6.2%Reduced
Vanguard Group Inc1,010,392$1.29M0.00%−11,378−1.1%Reduced
Jacobs Levy Equity Management, Inc666,574$849.9K0.00%+491,595+280.9%Added
Renaissance Technologies LLC634,500$809.0K0.00%+437,600+222.2%Added
Massachusetts Financial Services Co494,497$630.5K0.00%−55,033−10.0%Reduced
Acadian Asset Management LLC485,381$617.0K0.00%+411,238+554.7%Added
Millennium Management LLC462,555$589.8K0.00%+302,031+188.2%Added
Geode Capital Management, LLC402,336$513.0K0.00%+10,620+2.7%Added
Marshall Wace, LLP392,155$498.0K0.00%+33,018+9.2%Added
Morgan Stanley365,159$465.6K0.00%+41,470+12.8%Added
Two Sigma Advisers, LP300,000$382.5K0.00%+252,100+526.3%Added
State Street Corp293,396$374.1K0.00%+7,350+2.6%Added
Two Sigma Investments, LP231,839$295.6K0.00%+174,906+307.2%Added
Rhumbline Advisers166,830$212.7K0.00%+154,826+1,289.8%Added
TD Asset Management Inc160,652$204.8K0.00%00.0%Unchanged
Goldman Sachs Group Inc148,326$189.1K0.00%+53,165+55.9%Added
Deutsche Bank AG123,899$158.6K0.00%+109,281+747.6%Added
Charles Schwab Investment Management Inc117,200$149.4K0.00%−16,049−12.0%Reduced
Bridgeway Capital Management, LLC111,000$141.5K0.00%−65,100−37.0%Reduced
Northern Trust Corp83,387$106.3K0.00%−22,990−21.6%Reduced
Susquehanna International Group, LLP72,799$92.8K0.00%+72,799New
Manufacturers Life Insurance Company, The70,045$89.3K0.00%00.0%Unchanged
UBS Group AG67,390$85.9K0.00%+60,374+860.5%Added
Exchange Traded Concepts, LLC64,409$82.1K0.00%00.0%Unchanged
JPMorgan Chase & Co61,149$78.0K0.00%+55,183+925.0%Added
Cerity Partners LLC32,877$68.1K0.00%+20.0%Added
XTX Topco Ltd38,339$48.9K0.00%−9,900−20.5%Reduced
Barclays PLC29,773$38.0K0.00%+2,608+9.6%Added
Bank of New York Mellon Corp28,613$36.5K0.00%00.0%Unchanged
Bank of America Corp20,654$26.3K0.00%−4,290−17.2%Reduced
BNP Paribas Arbitrage, SA20,572$26.2K0.00%+20,572New
HSBC Holdings PLC20,640$25.6K0.00%−132−0.6%Reduced
Simplex Trading, LLC18,814$23.0K0.00%+9,482+101.6%Added
Nuveen Asset Management, LLC16,797$21.4K0.00%00.0%Unchanged
AQR Capital Management LLC12,493$15.9K0.00%+12,493New
JustInvest LLC11,925$15.2K0.00%+11,925New
Dimensional Fund Advisors LP10,981$13.9K0.00%−18,101−62.2%Reduced
Tower Research Capital LLC (TRC)10,376$13.2K0.00%+5,074+95.7%Added
Citadel Advisors LLC10,297$13.1K0.00%−4,928−32.4%Reduced
Citigroup Inc10,215$13.0K0.00%+560+5.8%Added
FMR LLC8,502$10.8K0.00%+884+11.6%Added
Wells Fargo & Company7,737$9.87K0.00%+1,684+27.8%Added
Mirae Asset Global ETFs Holdings Ltd.7,575$9.66K0.00%+304+4.2%Added
Corebridge Financial, Inc.6,554$8.36K0.00%−495−7.0%Reduced
Militia Capital Partners, LP4,300$5.48K0.00%+4,300New
New York State Common Retirement Fund3,622$4.62K0.00%00.0%Unchanged
Royal Bank of Canada3,721$4.00K0.00%+866+30.3%Added
SBI Securities Co., Ltd.2,741$3.50K0.00%+2,741New
CWM, LLC1,899$2.00K0.00%+1,889+18,890.0%Added
Legal & General Group Plc962$1.23K0.00%00.0%Unchanged
California State Teachers Retirement System955$1.22K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.819$1.04K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC508$6480.00%+508New
Group One Trading, L.P.500$6380.00%00.0%Unchanged
The PNC Financial Services Group, Inc.64$820.00%00.0%Unchanged
HighMark Wealth Management LLC50$640.00%00.0%Unchanged
Sterling Capital Management LLC42$540.00%00.0%Unchanged
Amalgamated Bank334$00.00%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)0$00.00%−3,766,120−100.0%Sold out
Boxer Capital, LLC0$00.00%−1,708,187−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−921,621−100.0%Sold out
Avidity Partners Management LP0$00.00%−890,000−100.0%Sold out
T. Rowe Price Investment Management, Inc.0$00.00%−281,583−100.0%Sold out
Walleye Capital LLC0$00.00%−83,175−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−40,102−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−20,048−100.0%Sold out
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−17,293−100.0%Sold out
Jump Financial, LLC0$00.00%−15,534−100.0%Sold out
Verition Fund Management LLC0$00.00%−11,295−100.0%Sold out
Jane Street Group, LLC0$00.00%−10,361−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−5,206−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−76−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−19−100.0%Sold out
Capital Performance Advisors LLP0$00.00%−8−100.0%Sold out