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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Prelude Therapeutics Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
60
+7 vs. Q3 2022
Shares held
31.2M
−643.3K (−2.0%) vs. Q3 2022
Total value
$188.3M
−$22.0M (−10.5%) vs. Q3 2022
New holders
12
13 more added
Sold out
5
24 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 60 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ4 2022: $188.3M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q3 2022.

Institutions holding PRLD in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP10,123,824$61.1M0.37%00.0%Unchanged
OrbiMed Advisors LLC10,039,691$60.6M1.16%00.0%Unchanged
FMR LLC4,589,592$27.7M0.00%−48,955−1.1%Reduced
UBS Asset Management Americas Inc2,335,944$14.1M0.01%−66,651−2.8%Reduced
Vanguard Group Inc899,314$5.43M0.00%+2690.0%Added
Massachusetts Financial Services Co514,971$3.11M0.00%+1,678+0.3%Added
BlackRock Inc.393,553$2.38M0.00%−65,581−14.3%Reduced
Price T Rowe Associates Inc300,677$1.82M0.00%−12,488−4.0%Reduced
Candriam Luxembourg S.C.A.179,850$1.09M0.01%+54,231+43.2%Added
Bank of America Corp157,824$953.3K0.00%−9,654−5.8%Reduced
Geode Capital Management, LLC144,677$873.0K0.00%−8,414−5.5%Reduced
Renaissance Technologies LLC136,500$824.0K0.00%−6,900−4.8%Reduced
State of Wisconsin Investment Board100,400$606.4K0.00%−8,700−8.0%Reduced
Susquehanna International Group, LLP93,290$563.5K0.00%+79,699+586.4%Added
Barclays PLC90,824$548.6K0.00%+85,656+1,657.4%Added
Morgan Stanley89,949$543.3K0.00%−87,839−49.4%Reduced
New York Life Investment Management LLC82,000$495.3K0.01%+8,607+11.7%Added
Two Sigma Advisers, LP75,300$454.8K0.00%−34,233−31.3%Reduced
D. E. Shaw & Co., Inc.68,005$410.8K0.00%−10,876−13.8%Reduced
Caxton Associates LP65,453$395.3K0.03%−20,539−23.9%Reduced
Charles Schwab Investment Management Inc63,721$384.9K0.00%+9,669+17.9%Added
Citigroup Inc60,072$362.8K0.00%+51,540+604.1%Added
Two Sigma Investments, LP51,898$313.5K0.00%−53,703−50.9%Reduced
Millennium Management LLC49,736$300.0K0.00%−10,690−17.7%Reduced
Gsa Capital Partners LLP47,801$289.0K0.04%−6,372−11.8%Reduced
State Street Corp43,889$265.1K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC36,949$223.2K0.01%00.0%Unchanged
Manufacturers Life Insurance Company, The34,298$191.1K0.00%+31+0.1%Added
Bank of New York Mellon Corp28,879$174.4K0.00%−300−1.0%Reduced
683 Capital Management, LLC28,631$172.9K0.02%+28,631New
TD Asset Management Inc28,440$171.8K0.00%00.0%Unchanged
Bleakley Financial Group, LLC22,325$134.8K0.00%+22,325New
Northern Trust Corp21,167$127.8K0.00%00.0%Unchanged
Man Group plc20,994$126.8K0.00%+20,994New
Citadel Advisors LLC18,232$110.1K0.00%+2,498+15.9%Added
Boothbay Fund Management, LLC17,623$106.4K0.00%+17,623New
Jane Street Group, LLC16,807$101.5K0.00%+16,807New
Mirabella Financial Services LLP16,058$97.0K0.01%+16,058New
Goldman Sachs Group Inc15,764$95.2K0.00%−5,971−27.5%Reduced
Commonwealth Equity Services, LLC15,307$92.0K0.00%−560−3.5%Reduced
Qube Research & Technologies Ltd13,127$79.3K0.00%+13,127New
Dimensional Fund Advisors LP12,759$77.0K0.00%−1,857−12.7%Reduced
Denali Advisors LLC8,200$49.5K0.02%00.0%Unchanged
Royal Bank of Canada4,299$26.0K0.00%+99+2.4%Added
Nisa Investment Advisors, LLC4,000$24.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,532$21.0K0.00%+2,278+181.7%Added
Dark Forest Capital Management LP3,092$18.7K0.00%+3,092New
Rockefeller Capital Management L.P.2,512$15.0K0.00%+2,512New
Cutler Group LP2,130$12.0K0.00%+2,130New
JPMorgan Chase & Co1,297$8.00K0.00%−1,154−47.1%Reduced
UBS Group AG1,037$6.26K0.00%+969+1,425.0%Added
Quantbot Technologies LP800$4.83K0.00%−600−42.9%Reduced
Advisor Group Holdings, Inc.500$3.00K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.370$2.23K0.00%−78−17.4%Reduced
Wells Fargo & Company342$2.07K0.00%−29−7.8%Reduced
Daiwa Securities Group Inc.104$1.00K0.00%00.0%Unchanged
Bessemer Group Inc89$1.00K0.00%+89New
FNY Investment Advisers, LLC200$1.00K0.00%+200New
Federated Hermes, Inc.65$3930.00%−1,342−95.4%Reduced
HighMark Wealth Management LLC50$3020.00%00.0%Unchanged
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)0$00.00%−583,333−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−24,180−100.0%Sold out
PDT Partners, LLC0$00.00%−12,641−100.0%Sold out
Simplex Trading, LLC0$00.00%−470−100.0%Sold out
Capital Advisors, Ltd. LLC0$00.00%−33−100.0%Sold out