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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Prelude Therapeutics Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
59
−2 vs. Q4 2024
Shares held
30.5M
−1.62M (−5.0%) vs. Q4 2024
Total value
$23.3M
−$17.7M (−43.2%) vs. Q4 2024
New holders
5
18 more added
Sold out
7
24 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 59 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ1 2025: $23.3M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q4 2024.

Institutions holding PRLD in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC10,909,256$8.38M0.20%00.0%Unchanged
Baker Bros. Advisors LP10,123,824$7.78M0.09%00.0%Unchanged
Boxer Capital Management, LLC2,108,014$1.62M0.49%+399,827+23.4%Added
BlackRock, Inc.1,047,725$804.7K0.00%−22,048−2.1%Reduced
Vanguard Group Inc1,009,204$775.1K0.00%−1,188−0.1%Reduced
Price T Rowe Associates Inc976,147$750.0K0.00%−53,052−5.2%Reduced
Renaissance Technologies LLC656,700$504.3K0.00%+22,200+3.5%Added
Acadian Asset Management LLC529,327$405.0K0.00%+43,946+9.1%Added
Geode Capital Management, LLC404,955$311.0K0.00%+2,619+0.7%Added
Morgan Stanley302,779$232.5K0.00%−62,380−17.1%Reduced
State Street Corp286,046$219.7K0.00%−7,350−2.5%Reduced
Two Sigma Advisers, LP260,400$200.0K0.00%−39,600−13.2%Reduced
Two Sigma Investments, LP183,667$141.1K0.00%−48,172−20.8%Reduced
TD Asset Management Inc160,652$123.4K0.00%00.0%Unchanged
Goldman Sachs Group Inc155,215$119.2K0.00%+6,889+4.6%Added
Millennium Management LLC146,770$112.7K0.00%−315,785−68.3%Reduced
Northern Trust Corp116,907$89.8K0.00%+33,520+40.2%Added
Charles Schwab Investment Management Inc114,050$87.6K0.00%−3,150−2.7%Reduced
UBS Group AG96,156$73.8K0.00%+28,766+42.7%Added
Bridgeway Capital Management, LLC88,500$68.0K0.00%−22,500−20.3%Reduced
Deutsche Bank AG80,723$62.2K0.00%−43,176−34.8%Reduced
Susquehanna International Group, LLP77,870$59.8K0.00%+5,071+7.0%Added
Manufacturers Life Insurance Company, The69,252$53.2K0.00%−793−1.1%Reduced
Marex Group plc56,270$43.2K0.00%+56,270New
Simplex Trading, LLC41,846$32.0K0.00%+23,032+122.4%Added
Cerity Partners LLC34,565$26.5K0.00%+1,688+5.1%Added
AQR Capital Management LLC33,823$26.0K0.00%+21,330+170.7%Added
Bank of New York Mellon Corp28,613$22.0K0.00%00.0%Unchanged
XTX Topco Ltd24,700$19.0K0.00%−13,639−35.6%Reduced
JPMorgan Chase & Co23,780$18.3K0.00%−37,369−61.1%Reduced
Barclays PLC23,145$17.8K0.00%−6,628−22.3%Reduced
HSBC Holdings PLC20,630$17.5K0.00%−100.0%Reduced
FMR LLC20,238$15.5K0.00%+11,736+138.0%Added
BNP Paribas Arbitrage, SA19,668$15.1K0.00%−904−4.4%Reduced
SG Americas Securities, LLC17,251$13.0K0.00%+17,251New
Rhumbline Advisers15,499$11.9K0.00%−151,331−90.7%Reduced
Bank of America Corp15,446$11.9K0.00%−5,208−25.2%Reduced
Tower Research Capital LLC (TRC)13,586$10.4K0.00%+3,210+30.9%Added
Citigroup Inc9,300$7.14K0.00%−915−9.0%Reduced
Wells Fargo & Company7,912$6.08K0.00%+175+2.3%Added
Mirae Asset Global ETFs Holdings Ltd.7,887$6.06K0.00%+312+4.1%Added
Corebridge Financial, Inc.6,458$4.96K0.00%−96−1.5%Reduced
Militia Capital Partners, LP4,300$3.30K0.00%00.0%Unchanged
CWM, LLC3,346$3.00K0.00%+1,447+76.2%Added
New York State Common Retirement Fund3,622$2.78K0.00%00.0%Unchanged
SBI Securities Co., Ltd.2,741$2.10K0.00%00.0%Unchanged
Royal Bank of Canada3,344$2.00K0.00%−377−10.1%Reduced
The PNC Financial Services Group, Inc.1,192$9150.00%+1,128+1,762.5%Added
Legal & General Group Plc962$7390.00%00.0%Unchanged
California State Teachers Retirement System955$7330.00%00.0%Unchanged
Ameritas Investment Partners, Inc.819$6290.00%00.0%Unchanged
Group One Trading, L.P.500$3840.00%00.0%Unchanged
Nisa Investment Advisors, LLC400$3070.00%−108−21.3%Reduced
Sterling Capital Management LLC227$1740.00%+185+440.5%Added
Citadel Advisors LLC34$260.00%−10,263−99.7%Reduced
True Wealth Design, LLC10$80.00%+10New
EverSource Wealth Advisors, LLC9$70.00%+9New
Amalgamated Bank334$00.00%00.0%Unchanged
Nuveen, LLC187,613––+187,613New
Jacobs Levy Equity Management, Inc0$00.00%−666,574−100.0%Sold out
Massachusetts Financial Services Co0$00.00%−494,497−100.0%Sold out
Marshall Wace, LLP0$00.00%−392,155−100.0%Sold out
Exchange Traded Concepts, LLC0$00.00%−64,409−100.0%Sold out
JustInvest LLC0$00.00%−11,925−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−10,981−100.0%Sold out
HighMark Wealth Management LLC0$00.00%−50−100.0%Sold out
Nuveen Asset Management, LLC––––Not filed