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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Prelude Therapeutics Inc as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
55
−5 vs. Q4 2022
Shares held
31.5M
+309.0K (+1.0%) vs. Q4 2022
Total value
$179.6M
−$8.69M (−4.6%) vs. Q4 2022
New holders
8
15 more added
Sold out
13
15 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 55 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ1 2023: $179.6M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q4 2022.

Institutions holding PRLD in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP10,123,824$57.7M0.31%00.0%Unchanged
OrbiMed Advisors LLC10,039,691$57.2M1.13%00.0%Unchanged
FMR LLC4,546,678$25.9M0.00%−42,914−0.9%Reduced
UBS Asset Management Americas Inc2,273,894$13.0M0.01%−62,050−2.7%Reduced
Vanguard Group Inc916,014$5.22M0.00%+16,700+1.9%Added
Boxer Capital, LLC699,047$3.98M0.20%+699,047New
Massachusetts Financial Services Co514,548$2.93M0.00%−423−0.1%Reduced
BlackRock Inc.423,028$2.41M0.00%+29,475+7.5%Added
Price T Rowe Associates Inc284,362$1.62M0.00%−16,315−5.4%Reduced
Geode Capital Management, LLC145,904$831.7K0.00%+1,227+0.8%Added
Morgan Stanley141,662$807.5K0.00%+51,713+57.5%Added
Renaissance Technologies LLC138,500$789.0K0.00%+2,000+1.5%Added
Millennium Management LLC136,519$778.0K0.00%+86,783+174.5%Added
Susquehanna International Group, LLP129,680$739.2K0.00%+36,390+39.0%Added
State of Wisconsin Investment Board90,200$514.1K0.00%−10,200−10.2%Reduced
Jacobs Levy Equity Management, Inc84,667$482.6K0.00%+84,667New
Citigroup Inc70,767$403.4K0.00%+10,695+17.8%Added
Jane Street Group, LLC64,470$367.5K0.00%+47,663+283.6%Added
Charles Schwab Investment Management Inc62,851$358.3K0.00%−870−1.4%Reduced
Two Sigma Advisers, LP50,500$287.9K0.00%−24,800−32.9%Reduced
Goldman Sachs Group Inc49,496$282.1K0.00%+33,732+214.0%Added
Gsa Capital Partners LLP47,614$271.0K0.03%−187−0.4%Reduced
D. E. Shaw & Co., Inc.47,249$269.3K0.00%−20,756−30.5%Reduced
State Street Corp43,889$250.2K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC36,949$210.6K0.01%00.0%Unchanged
Manufacturers Life Insurance Company, The34,298$195.5K0.00%00.0%Unchanged
Qube Research & Technologies Ltd30,377$173.1K0.00%+17,250+131.4%Added
683 Capital Management, LLC28,631$163.2K0.01%00.0%Unchanged
TD Asset Management Inc28,440$162.1K0.00%00.0%Unchanged
Bank of America Corp28,186$160.7K0.00%−129,638−82.1%Reduced
Man Group plc–$129.2K0.00%––
Two Sigma Investments, LP22,455$128.0K0.00%−29,443−56.7%Reduced
HRT Financial LP22,175$126.0K0.00%+22,175New
Northern Trust Corp21,167$120.7K0.00%00.0%Unchanged
Boothbay Fund Management, LLC16,198$92.3K0.00%−1,425−8.1%Reduced
Tower Research Capital LLC (TRC)13,352$76.0K0.00%+9,820+278.0%Added
Dimensional Fund Advisors LP12,759$72.7K0.00%00.0%Unchanged
Virtu Financial LLC11,201$64.0K0.01%+11,201New
Two Sigma Securities, LLC10,922$62.3K0.01%+10,922New
Barclays PLC10,322$58.8K0.00%−80,502−88.6%Reduced
Cubist Systematic Strategies, LLC8,778$50.0K0.00%+8,778New
Denali Advisors LLC8,200$46.7K0.02%00.0%Unchanged
Royal Bank of Canada5,258$30.0K0.00%+959+22.3%Added
Nisa Investment Advisors, LLC4,000$23.0K0.00%00.0%Unchanged
Cutler Group LP2,130$12.0K0.00%00.0%Unchanged
Point72 Middle East FZE1,680$9.58K0.00%+1,680New
JPMorgan Chase & Co1,394$8.00K0.00%+97+7.5%Added
Point72 Asset Management, L.P.1,222$6.96K0.00%+1,222New
UBS Group AG980$5.59K0.00%−57−5.5%Reduced
China Universal Asset Management Co., Ltd.649$3.70K0.00%+279+75.4%Added
Advisor Group Holdings, Inc.500$2.85K0.00%00.0%Unchanged
Wells Fargo & Company178$1.01K0.00%−164−48.0%Reduced
Bessemer Group Inc89$1.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.104$1.00K0.00%00.0%Unchanged
HighMark Wealth Management LLC50$2850.00%00.0%Unchanged
Candriam Luxembourg S.C.A.0$00.00%−179,850−100.0%Sold out
New York Life Investment Management LLC0$00.00%−82,000−100.0%Sold out
Caxton Associates LP0$00.00%−65,453−100.0%Sold out
Bank of New York Mellon Corp0$00.00%−28,879−100.0%Sold out
Bleakley Financial Group, LLC0$00.00%−22,325−100.0%Sold out
Citadel Advisors LLC0$00.00%−18,232−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−16,058−100.0%Sold out
Commonwealth Equity Services, LLC0$00.00%−15,307−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−3,092−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−2,512−100.0%Sold out
Quantbot Technologies LP0$00.00%−800−100.0%Sold out
FNY Investment Advisers, LLC0$00.00%−200−100.0%Sold out
Federated Hermes, Inc.0$00.00%−65−100.0%Sold out