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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Prelude Therapeutics Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
68
−7 vs. Q4 2021
Shares held
34.1M
−1.04M (−3.0%) vs. Q4 2021
Total value
$235.4M
−$202.3M (−46.2%) vs. Q4 2021
New holders
12
19 more added
Sold out
19
25 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 68 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ1 2022: $235.4M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q4 2021.

Institutions holding PRLD in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP10,123,824$69.9M0.40%00.0%Unchanged
OrbiMed Advisors LLC10,039,691$69.3M1.12%00.0%Unchanged
FMR LLC5,371,907$37.1M0.00%−567,026−9.5%Reduced
UBS Asset Management Americas Inc2,422,327$16.7M0.01%+908,641+60.0%Added
BlackRock Inc.1,051,960$7.26M0.00%+155,456+17.3%Added
Vanguard Group Inc800,498$5.52M0.00%+29,058+3.8%Added
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)583,333$4.03M0.08%00.0%Unchanged
Morgan Stanley546,475$3.77M0.00%−299,239−35.4%Reduced
Massachusetts Financial Services Co482,119$3.33M0.00%+13,322+2.8%Added
Rock Springs Capital Management LP368,959$2.55M0.06%00.0%Unchanged
Price T Rowe Associates Inc322,988$2.23M0.00%+18,656+6.1%Added
State Street Corp209,861$1.45M0.00%+1,455+0.7%Added
Geode Capital Management, LLC207,576$1.43M0.00%−5,060−2.4%Reduced
Two Sigma Investments, LP180,412$1.25M0.00%−102,362−36.2%Reduced
Bank of America Corp135,237$933.0K0.00%+56,755+72.3%Added
Two Sigma Advisers, LP126,500$873.0K0.00%+42,200+50.1%Added
Marshall Wace, LLP111,777$772.0K0.00%−156,241−58.3%Reduced
Northern Trust Corp101,906$703.0K0.00%−5,278−4.9%Reduced
Charles Schwab Investment Management Inc75,930$524.0K0.00%−9,207−10.8%Reduced
State of Wisconsin Investment Board74,500$514.0K0.00%+61,200+460.2%Added
PDT Partners, LLC71,822$496.0K0.04%+35,915+100.0%Added
Nuveen Asset Management, LLC66,421$490.0K0.00%+25,904+63.9%Added
Bank of New York Mellon Corp59,820$412.0K0.00%+2,144+3.7%Added
IndexIQ Advisors LLC56,750$392.0K0.01%+56,750New
Citadel Advisors LLC50,898$352.0K0.00%−87,602−63.3%Reduced
Renaissance Technologies LLC40,100$277.0K0.00%−87,100−68.5%Reduced
Millennium Management LLC39,311$271.0K0.00%−404,800−91.1%Reduced
Manufacturers Life Insurance Company, The34,267$238.4K0.00%+34,267New
Squarepoint Ops LLC31,334$216.0K0.00%−17,333−35.6%Reduced
Swiss National Bank29,700$205.0K0.00%+2,200+8.0%Added
TD Asset Management Inc28,440$196.0K0.00%00.0%Unchanged
Occudo Quantitative Strategies LP24,238$167.0K0.01%+2,845+13.3%Added
Goldman Sachs Group Inc24,090$166.0K0.00%−89,245−78.7%Reduced
D. E. Shaw & Co., Inc.23,611$163.0K0.00%+23,611New
Gsa Capital Partners LLP23,201$160.0K0.02%+23,201New
Alliancebernstein L.P.21,500$148.0K0.00%−1,968−8.4%Reduced
Commonwealth Equity Services, LLC20,467$141.0K0.00%−2,365−10.4%Reduced
California State Teachers Retirement System15,316$106.0K0.00%−1,154−7.0%Reduced
Virtus ETF Advisers LLC13,048$90.0K0.04%−767−5.6%Reduced
Voloridge Investment Management, LLC11,743$81.0K0.00%−27,271−69.9%Reduced
Corton Capital Inc.10,918$75.0K0.03%+10,918New
Rhumbline Advisers10,050$69.0K0.00%+10,050New
JPMorgan Chase & Co9,264$64.0K0.00%+2,040+28.2%Added
Ensign Peak Advisors, Inc8,080$56.0K0.00%00.0%Unchanged
Deutsche Bank AG6,187$43.0K0.00%−700−10.2%Reduced
Barclays PLC5,877$40.0K0.00%+5,877New
American International Group, Inc.5,373$37.0K0.00%−378−6.6%Reduced
New York State Common Retirement Fund4,992$34.0K0.00%−4,100−45.1%Reduced
Legal & General Group Plc3,914$27.0K0.00%00.0%Unchanged
Royal Bank of Canada3,166$22.0K0.00%−1,666−34.5%Reduced
Tower Research Capital LLC (TRC)2,335$16.0K0.00%−2,985−56.1%Reduced
STRS Ohio2,200$15.0K0.00%00.0%Unchanged
Citigroup Inc1,719$12.0K0.00%−2,359−57.8%Reduced
Brewin Dolphin Wealth Management Ltd1,699$12.0K0.00%00.0%Unchanged
Amalgamated Bank1,764$12.0K0.00%+1,764New
Amalgamated Financial Corp.1,764$12.0K0.00%+1,764New
Lindbrook Capital, LLC1,562$11.0K0.00%+1,471+1,616.5%Added
Simplex Trading, LLC1,561$10.0K0.00%+1,561New
Signaturefd, LLC992$7.00K0.00%+764+335.1%Added
Ameritas Investment Partners, Inc.769$5.00K0.00%00.0%Unchanged
Dravo Bay LLC650$4.49K0.00%+650New
US Bancorp606$4.00K0.00%+424+233.0%Added
Advisor Group Holdings, Inc.365$2.00K0.00%+25+7.4%Added
Wells Fargo & Company100$1.00K0.00%−3,052−96.8%Reduced
UBS Group AG183$1.00K0.00%−1,755−90.6%Reduced
Daiwa Securities Group Inc.104$1.00K0.00%00.0%Unchanged
HighMark Wealth Management LLC50$00.00%00.0%Unchanged
Cutler Group LP100$00.00%+100New
Jacobs Levy Equity Management, Inc0$00.00%−130,280−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−116,303−100.0%Sold out
HRT Financial LP0$00.00%−114,249−100.0%Sold out
Pinz Capital Management, LP0$00.00%−43,800−100.0%Sold out
Walleye Capital LLC0$00.00%−41,954−100.0%Sold out
Jump Financial, LLC0$00.00%−36,900−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−29,275−100.0%Sold out
Norges Bank0$00.00%−25,000−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−23,384−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−21,900−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−20,773−100.0%Sold out
Nan Fung Group Holdings Ltd0$00.00%−20,350−100.0%Sold out
Trexquant Investment LP0$00.00%−19,458−100.0%Sold out
Parkwood LLC0$00.00%−12,667−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−12,594−100.0%Sold out
Jane Street Group, LLC0$00.00%−10,241−100.0%Sold out
Quantbot Technologies LP0$00.00%−8,200−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−3,872−100.0%Sold out
State of Wyoming0$00.00%−544−100.0%Sold out