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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Prelude Therapeutics Inc as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
56
−4 vs. Q3 2023
Shares held
34.7M
−1.89M (−5.2%) vs. Q3 2023
Total value
$148.3M
+$35.1M (+31.1%) vs. Q3 2023
New holders
6
29 more added
Sold out
10
14 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 56 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ4 2023: $148.3M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q3 2023.

Institutions holding PRLD in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC10,909,256$46.6M0.93%00.0%Unchanged
Baker Bros. Advisors LP10,123,824$43.2M0.49%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)4,133,000$17.6M0.33%+4,133,000New
Boxer Capital, LLC2,568,287$11.0M0.55%+73,269+2.9%Added
BlackRock Inc.1,095,589$4.68M0.00%+27,155+2.5%Added
Price T Rowe Associates Inc1,042,737$4.45M0.00%−24,121−2.3%Reduced
Vanguard Group Inc1,006,856$4.30M0.00%+33,250+3.4%Added
Massachusetts Financial Services Co510,749$2.18M0.00%+470+0.1%Added
Geode Capital Management, LLC349,367$1.49M0.00%+18,267+5.5%Added
Sio Capital Management, LLC320,394$1.37M0.35%−29,606−8.5%Reduced
Morgan Stanley298,796$1.28M0.00%+54,326+22.2%Added
FMR LLC264,687$1.13M0.00%−4,866,746−94.8%Reduced
Renaissance Technologies LLC216,400$924.0K0.00%+77,026+55.3%Added
State Street Corp212,234$906.2K0.00%+25,025+13.4%Added
TD Asset Management Inc160,652$686.0K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC148,749$635.2K0.01%+111,800+302.6%Added
Jacobs Levy Equity Management, Inc131,307$560.7K0.00%−12,650−8.8%Reduced
Charles Schwab Investment Management Inc124,700$532.5K0.00%+1,669+1.4%Added
Northern Trust Corp114,097$487.2K0.00%−1,421−1.2%Reduced
Millennium Management LLC96,966$414.0K0.00%+33,099+51.8%Added
Citadel Advisors LLC95,330$407.1K0.00%−204,771−68.2%Reduced
Manufacturers Life Insurance Company, The70,165$299.6K0.00%00.0%Unchanged
Goldman Sachs Group Inc69,465$296.6K0.00%+1,777+2.6%Added
Pale Fire Capital SE63,581$271.5K0.04%+32,800+106.6%Added
Two Sigma Advisers, LP61,800$263.9K0.00%+30,700+98.7%Added
Two Sigma Investments, LP58,284$248.9K0.00%+45,471+354.9%Added
Bank of New York Mellon Corp50,600$216.1K0.00%+17,718+53.9%Added
Exchange Traded Concepts, LLC44,087$188.3K0.01%+11,180+34.0%Added
Bank of America Corp37,490$160.1K0.00%−15,157−28.8%Reduced
Jane Street Group, LLC32,977$140.8K0.00%+32,977New
Barclays PLC30,526$130.3K0.00%+17,210+129.2%Added
Squarepoint Ops LLC29,418$125.6K0.00%−59,384−66.9%Reduced
State of Wisconsin Investment Board24,800$105.9K0.00%−36,800−59.7%Reduced
HSBC Holdings PLC23,210$93.8K0.00%+12+0.1%Added
Rhumbline Advisers20,403$87.1K0.00%−13,412−39.7%Reduced
New York State Common Retirement Fund20,122$85.9K0.00%−27−0.1%Reduced
UBS Group AG19,873$84.9K0.00%+12,465+168.3%Added
Nuveen Asset Management, LLC16,797$71.7K0.00%+2,993+21.7%Added
Acadian Asset Management LLC15,495$65.0K0.00%+8,472+120.6%Added
Amundi15,130$61.4K0.00%+15,130New
Prelude Capital Management, LLC14,346$61.3K0.01%+14,346New
Dimensional Fund Advisors LP14,305$60.9K0.00%+3,117+27.9%Added
Virtu Financial LLC13,607$58.0K0.00%+13,607New
SG Americas Securities, LLC13,100$56.0K0.00%+13,100New
JPMorgan Chase & Co9,380$40.1K0.00%−7,973−45.9%Reduced
Royal Bank of Canada9,040$39.0K0.00%+3,977+78.6%Added
American International Group, Inc.7,397$31.6K0.00%+295+4.2%Added
Wells Fargo & Company4,599$19.6K0.00%+963+26.5%Added
Tower Research Capital LLC (TRC)3,992$17.0K0.00%+492+14.1%Added
California State Teachers Retirement System2,449$10.5K0.00%−691−22.0%Reduced
Citigroup Inc2,127$9.08K0.00%+1,601+304.4%Added
Legal & General Group Plc962$4.11K0.00%00.0%Unchanged
Amalgamated Bank864$4.00K0.00%−100−10.4%Reduced
Ameritas Investment Partners, Inc.819$3.50K0.00%00.0%Unchanged
HighMark Wealth Management LLC50$2140.00%00.0%Unchanged
Simplex Trading, LLC67$00.00%+36+116.1%Added
EcoR1 Capital, LLC0$00.00%−1,157,452−100.0%Sold out
Woodline Partners LP0$00.00%−200,000−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−70,583−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−49,184−100.0%Sold out
Allspring Global Investments Holdings, LLC0$00.00%−6,107−100.0%Sold out
China Universal Asset Management Co., Ltd.0$00.00%−1,076−100.0%Sold out
Deutsche Bank AG0$00.00%−446−100.0%Sold out
Nisa Investment Advisors, LLC0$00.00%−37−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−104−100.0%Sold out
Cutler Group LP0$00.00%−130−100.0%Sold out