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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Prelude Therapeutics Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
75
+14 vs. Q3 2021
Shares held
35.2M
−815.4K (−2.3%) vs. Q3 2021
Total value
$437.6M
−$686.3M (−61.1%) vs. Q3 2021
New holders
26
27 more added
Sold out
12
14 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 75 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ4 2021: $437.6M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q3 2021.

Institutions holding PRLD in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP10,123,824$126.0M0.61%00.0%Unchanged
OrbiMed Advisors LLC10,039,691$125.0M1.62%00.0%Unchanged
FMR LLC5,938,933$73.9M0.01%−1,116,733−15.8%Reduced
UBS Asset Management Americas Inc1,513,686$18.8M0.01%+30,367+2.0%Added
BlackRock Inc.896,504$11.2M0.00%+170,542+23.5%Added
Morgan Stanley845,714$10.5M0.00%+88,927+11.8%Added
Vanguard Group Inc771,440$9.60M0.00%−365,282−32.1%Reduced
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)583,333$7.26M0.11%00.0%Unchanged
Massachusetts Financial Services Co468,797$5.84M0.00%−3,449−0.7%Reduced
Millennium Management LLC444,111$5.53M0.01%+403,260+987.1%Added
Rock Springs Capital Management LP368,959$4.59M0.11%+6,600+1.8%Added
Price T Rowe Associates Inc304,332$3.79M0.00%−90,944−23.0%Reduced
Two Sigma Investments, LP282,774$3.52M0.01%+282,774New
Marshall Wace, LLP268,018$3.34M0.01%+268,018New
Geode Capital Management, LLC212,636$2.65M0.00%−36,536−14.7%Reduced
State Street Corp208,406$2.60M0.00%−642,077−75.5%Reduced
Citadel Advisors LLC138,500$1.73M0.00%+124,005+855.5%Added
Jacobs Levy Equity Management, Inc130,280$1.62M0.01%+130,280New
Renaissance Technologies LLC127,200$1.58M0.00%+127,200New
Cubist Systematic Strategies, LLC116,303$1.45M0.01%+94,548+434.6%Added
HRT Financial LP114,249$1.42M0.01%+98,690+634.3%Added
Goldman Sachs Group Inc113,335$1.41M0.00%+104,676+1,208.9%Added
Northern Trust Corp107,184$1.33M0.00%+759+0.7%Added
Charles Schwab Investment Management Inc85,137$1.06M0.00%+1,152+1.4%Added
Two Sigma Advisers, LP84,300$1.05M0.00%+84,300New
Bank of America Corp78,482$977.0K0.00%+71,387+1,006.2%Added
Bank of New York Mellon Corp57,676$718.0K0.00%+23,364+68.1%Added
Squarepoint Ops LLC48,667$606.0K0.00%+48,667New
Pinz Capital Management, LP43,800$545.0K0.21%+43,800New
Walleye Capital LLC41,954$522.0K0.02%+41,954New
Nuveen Asset Management, LLC40,517$504.0K0.00%−4,882−10.8%Reduced
Voloridge Investment Management, LLC39,014$486.0K0.00%+39,014New
Jump Financial, LLC36,900$459.0K0.03%+36,900New
PDT Partners, LLC35,907$447.0K0.03%+35,907New
Susquehanna International Group, LLP29,275$364.0K0.00%+9,645+49.1%Added
TD Asset Management Inc28,440$354.0K0.00%00.0%Unchanged
Swiss National Bank27,500$342.0K0.00%+7,000+34.1%Added
Norges Bank25,000$311.0K0.00%−197,400−88.8%Reduced
Alliancebernstein L.P.23,468$292.0K0.00%+9,768+71.3%Added
Qube Research & Technologies Ltd23,384$291.0K0.00%+23,384New
Commonwealth Equity Services, LLC22,832$284.0K0.00%+9,350+69.4%Added
Susquehanna Fundamental Investments, LLC21,900$273.0K0.01%+21,900New
Occudo Quantitative Strategies LP21,393$266.0K0.02%+21,393New
ExodusPoint Capital Management, LP20,773$259.0K0.00%+20,773New
Nan Fung Group Holdings Ltd20,350$253.0K0.07%+20,350New
Trexquant Investment LP19,458$242.0K0.01%+19,458New
California State Teachers Retirement System16,470$205.0K0.00%+2,946+21.8%Added
Virtus ETF Advisers LLC13,815$172.0K0.06%+7,523+119.6%Added
State of Wisconsin Investment Board13,300$166.0K0.00%00.0%Unchanged
Parkwood LLC12,667$158.0K0.03%+12,667New
Thrivent Financial for Lutherans12,594$157.0K0.00%+12,594New
Jane Street Group, LLC10,241$128.0K0.00%+10,241New
New York State Common Retirement Fund9,092$113.0K0.00%−17−0.2%Reduced
Quantbot Technologies LP8,200$102.0K0.01%+8,000+4,000.0%Added
Ensign Peak Advisors, Inc8,080$101.0K0.00%+8,080New
JPMorgan Chase & Co7,224$91.0K0.00%+205+2.9%Added
Deutsche Bank AG6,887$86.0K0.00%+350+5.4%Added
American International Group, Inc.5,751$72.0K0.00%−172−2.9%Reduced
Tower Research Capital LLC (TRC)5,320$66.0K0.00%+1,821+52.0%Added
Royal Bank of Canada4,832$61.0K0.00%−74−1.5%Reduced
Citigroup Inc4,078$51.0K0.00%−20,190−83.2%Reduced
Legal & General Group Plc3,914$49.0K0.00%+956+32.3%Added
Point72 Hong Kong Ltd3,872$48.0K0.00%+2,270+141.7%Added
Wells Fargo & Company3,152$39.0K0.00%+3,109+7,230.2%Added
STRS Ohio2,200$27.0K0.00%00.0%Unchanged
UBS Group AG1,938$23.0K0.00%−35,063−94.8%Reduced
Brewin Dolphin Wealth Management Ltd1,699$21.0K0.00%+1,699New
Ameritas Investment Partners, Inc.769$10.0K0.00%00.0%Unchanged
State of Wyoming544$7.00K0.00%−29−5.1%Reduced
Advisor Group Holdings, Inc.340$4.00K0.00%00.0%Unchanged
Signaturefd, LLC228$3.00K0.00%+228New
US Bancorp182$2.00K0.00%+24+15.2%Added
Daiwa Securities Group Inc.104$1.00K0.00%+104New
Lindbrook Capital, LLC91$1.00K0.00%+91New
HighMark Wealth Management LLC50$1.00K0.00%+50New
Parallel Advisors, LLC0$00.00%−38−100.0%Sold out
Federated Hermes, Inc.0$00.00%−408,100−100.0%Sold out
Logos Global Management LP0$00.00%−400,000−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−36,936−100.0%Sold out
Parametric Portfolio Associates LLC0$00.00%−10,130−100.0%Sold out
Rhumbline Advisers0$00.00%−9,275−100.0%Sold out
SG Americas Securities, LLC0$00.00%−8,691−100.0%Sold out
Virtu Financial LLC0$00.00%−7,940−100.0%Sold out
Credit Suisse AG0$00.00%−6,950−100.0%Sold out
MetLife Investment Management0$00.00%−4,148−100.0%Sold out
Metropolitan Life Insurance Co0$00.00%−3,194−100.0%Sold out
Jacobi Capital Management LLC0$00.00%−250−100.0%Sold out