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Prelude Therapeutics Inc

PRLD
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001678660

No open-market purchases or sales by Prelude Therapeutics Inc insiders were filed in the last 90 days; 75 institutions reported holding it in 13F filings for Q2 2026, worth $264.3M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Prelude Therapeutics Inc as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
53
−8 vs. Q2 2022
Shares held
31.8M
−913.7K (−2.8%) vs. Q2 2022
Total value
$210.3M
+$39.5M (+23.1%) vs. Q2 2022
New holders
5
16 more added
Sold out
13
20 more reduced

1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PRLD on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 53 institutions
Q1 2021: 60 institutionsQ2 2021: 57 institutionsQ3 2021: 61 institutionsQ4 2021: 75 institutionsQ1 2022: 68 institutionsQ2 2022: 62 institutionsQ3 2022: 53 institutionsQ4 2022: 60 institutionsQ1 2023: 55 institutionsQ2 2023: 55 institutionsQ3 2023: 60 institutionsQ4 2023: 56 institutionsQ1 2024: 58 institutionsQ2 2024: 61 institutionsQ3 2024: 70 institutionsQ4 2024: 62 institutionsQ1 2025: 59 institutionsQ2 2025: 50 institutionsQ3 2025: 47 institutionsQ4 2025: 48 institutionsQ1 2026: 55 institutionsQ2 2026: 75 institutions
Value heldQ3 2022: $210.3M
Q1 2021: $1.41BQ2 2021: $986.6MQ3 2021: $1.12BQ4 2021: $437.6MQ1 2022: $235.4MQ2 2022: $170.9MQ3 2022: $210.3MQ4 2022: $188.3MQ1 2023: $179.6MQ2 2023: $176.2MQ3 2023: $113.1MQ4 2023: $148.3MQ1 2024: $162.1MQ2 2024: $129.2MQ3 2024: $74.0MQ4 2024: $41.0MQ1 2025: $23.3MQ2 2025: $22.0MQ3 2025: $39.1MQ4 2025: $82.6MQ1 2026: $105.2MQ2 2026: $264.3M
Institutions holding PRLD and their total value by quarter
QuarterHoldersValue
Q2 202675$264.3M
Q1 202655$105.2M
Q4 202548$82.6M
Q3 202547$39.1M
Q2 202550$22.0M
Q1 202559$23.3M
Q4 202462$41.0M
Q3 202470$74.0M
Q2 202461$129.2M
Q1 202458$162.1M
Q4 202356$148.3M
Q3 202360$113.1M
Q2 202355$176.2M
Q1 202355$179.6M
Q4 202260$188.3M
Q3 202253$210.3M
Q2 202262$170.9M
Q1 202268$235.4M
Q4 202175$437.6M
Q3 202161$1.12B
Q2 202157$986.6M
Q1 202160$1.41B

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Prelude Therapeutics Inc; share changes are against Q2 2022.

Institutions holding PRLD in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP10,123,824$66.9M0.44%00.0%Unchanged
OrbiMed Advisors LLC10,039,691$66.4M1.32%00.0%Unchanged
FMR LLC4,638,547$30.7M0.00%+335,578+7.8%Added
UBS Asset Management Americas Inc2,402,595$15.9M0.01%−17,932−0.7%Reduced
Vanguard Group Inc899,045$5.94M0.00%00.0%Unchanged
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)583,333$3.86M0.10%00.0%Unchanged
Massachusetts Financial Services Co513,293$3.39M0.00%+34,768+7.3%Added
BlackRock Inc.459,134$3.03M0.00%−70,301−13.3%Reduced
Price T Rowe Associates Inc313,165$2.07M0.00%+5,812+1.9%Added
Morgan Stanley177,788$1.18M0.00%−303,000−63.0%Reduced
Bank of America Corp167,478$1.11M0.00%+33,983+25.5%Added
Geode Capital Management, LLC153,091$1.01M0.00%+17,450+12.9%Added
Renaissance Technologies LLC143,400$948.0K0.00%−17,086−10.6%Reduced
Candriam Luxembourg S.C.A.125,619$830.0K0.01%+125,619New
Two Sigma Advisers, LP109,533$724.0K0.00%−126,167−53.5%Reduced
State of Wisconsin Investment Board109,100$721.0K0.00%−18,100−14.2%Reduced
Two Sigma Investments, LP105,601$698.0K0.00%−118,235−52.8%Reduced
Caxton Associates LP85,992$568.0K0.10%+2,125+2.5%Added
D. E. Shaw & Co., Inc.78,881$521.0K0.00%−36,986−31.9%Reduced
New York Life Investment Management LLC73,393$485.0K0.01%+5,808+8.6%Added
Millennium Management LLC60,426$399.0K0.00%−30,511−33.6%Reduced
Charles Schwab Investment Management Inc54,052$358.0K0.00%−9,148−14.5%Reduced
Gsa Capital Partners LLP54,173$358.0K0.05%+17,547+47.9%Added
State Street Corp43,889$290.0K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC36,949$244.0K0.01%−10,000−21.3%Reduced
Manufacturers Life Insurance Company, The34,267$223.5K0.00%00.0%Unchanged
Bank of New York Mellon Corp29,179$193.0K0.00%−100.0%Reduced
TD Asset Management Inc28,440$185.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC24,180$160.0K0.06%+175+0.7%Added
Goldman Sachs Group Inc21,735$144.0K0.00%−22,560−50.9%Reduced
Northern Trust Corp21,167$140.0K0.00%00.0%Unchanged
Citadel Advisors LLC15,734$104.0K0.00%−93,889−85.6%Reduced
Commonwealth Equity Services, LLC15,867$104.0K0.00%−750−4.5%Reduced
Dimensional Fund Advisors LP14,616$97.0K0.00%+14,616New
Susquehanna International Group, LLP13,591$90.0K0.00%−15,837−53.8%Reduced
PDT Partners, LLC12,641$84.0K0.01%−31,090−71.1%Reduced
Citigroup Inc8,532$56.0K0.00%+7,691+914.5%Added
Denali Advisors LLC8,200$54.0K0.03%+8,200New
Barclays PLC5,168$34.0K0.00%+1,108+27.3%Added
Royal Bank of Canada4,200$28.0K0.00%+1,699+67.9%Added
Nisa Investment Advisors, LLC4,000$27.0K0.00%00.0%Unchanged
JPMorgan Chase & Co2,451$16.0K0.00%+418+20.6%Added
Tower Research Capital LLC (TRC)1,254$9.00K0.00%−2,770−68.8%Reduced
Quantbot Technologies LP1,400$9.00K0.00%−1,400−50.0%Reduced
Federated Hermes, Inc.1,407$9.00K0.00%+1,141+428.9%Added
Advisor Group Holdings, Inc.500$3.00K0.00%00.0%Unchanged
Simplex Trading, LLC470$3.00K0.00%+470New
China Universal Asset Management Co., Ltd.448$3.00K0.00%+448New
Wells Fargo & Company371$2.00K0.00%+184+98.4%Added
Daiwa Securities Group Inc.104$1.00K0.00%00.0%Unchanged
UBS Group AG68$00.00%−2,638−97.5%Reduced
Capital Advisors, Ltd. LLC33$00.00%+22+200.0%Added
HighMark Wealth Management LLC50$00.00%00.0%Unchanged
Rock Springs Capital Management LP0$00.00%−368,959−100.0%Sold out
Marshall Wace, LLP0$00.00%−45,716−100.0%Sold out
Ergoteles LLC0$00.00%−43,500−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−39,938−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−23,640−100.0%Sold out
Squarepoint Ops LLC0$00.00%−19,618−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−18,000−100.0%Sold out
Delphia (USA) Inc.0$00.00%−16,940−100.0%Sold out
Corton Capital Inc.0$00.00%−15,586−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−8,080−100.0%Sold out
New York State Common Retirement Fund0$00.00%−92−100.0%Sold out
Credit Suisse AG0$00.00%−6−100.0%Sold out
Cutler Group LP0$00.00%−100−100.0%Sold out
Brewin Dolphin Wealth Management Ltd––––Not filed