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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Opko Health, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
−8 vs. Q1 2026
Shares held
202.4M
+1.61M (+0.8%) vs. Q1 2026
Total value
$303.4M
+$74.5M (+32.5%) vs. Q1 2026
New holders
23
74 more added
Sold out
31
52 more reduced

6 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 222 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ2 2026: $303.4M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2026.

Institutions holding OPK in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
OP Asset Management Ltd1,159,647$1.74M0.02%+57,393+5.2%Added
AQR Capital Management LLC1,239,399$1.86M0.00%+475,809+62.3%Added
Y.D. More Investments Ltd1,257,568$1.88M0.06%−41,905−3.2%Reduced
Dimensional Fund Advisors LP1,267,741$1.90M0.00%−292,259−18.7%Reduced
Bank of New York Mellon Corp1,329,974$1.99M0.00%+49,932+3.9%Added
Washington Growth Strategies LLC1,356,124$2.03M1.13%00.0%Unchanged
Citadel Advisors LLC1,420,922$2.13M0.00%−658,625−31.7%Reduced
Morgan Stanley1,975,027$2.96M0.00%+778,940+65.1%Added
AWM Investment Company, Inc.2,110,000$3.17M0.27%+10,000+0.5%Added
Vanguard Fiduciary Trust Co2,706,235$4.06M0.00%−35,782−1.3%Reduced
Charles Schwab Investment Management Inc3,596,980$5.40M0.00%+22,941+0.6%Added
Highbridge Capital Management LLC3,593,925$5.43M0.19%+3,593,925New
Northern Trust Corp3,756,163$5.63M0.00%+136,817+3.8%Added
Whitefort Capital Management, LP4,511,412$6.77M1.67%+258,072+6.1%Added
UBS Group AG5,006,284$7.51M0.00%−1,065,148−17.5%Reduced
Goldman Sachs Group Inc7,035,492$10.6M0.00%−639,534−8.3%Reduced
State Street Corp10,309,070$15.5M0.00%+807,693+8.5%Added
Geode Capital Management, LLC11,581,027$17.4M0.00%+279,526+2.5%Added
Vanguard Portfolio Management LLC14,934,924$22.4M0.00%+165,205+1.1%Added
Vanguard Capital Management LLC14,968,930$22.5M0.00%+469,766+3.2%Added
BlackRock, Inc.36,978,893$55.5M0.00%+746,670+2.1%Added
Rubric Capital Management LP47,791,243$71.7M0.66%00.0%Unchanged
Tejara Capital Ltd0$00.00%−877,941−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−663,704−100.0%Sold out
First Trust Advisors LP0$00.00%−500,273−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−404,358−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−342,171−100.0%Sold out
Renaissance Technologies LLC0$00.00%−109,543−100.0%Sold out
HRT Financial LP0$00.00%−90,759−100.0%Sold out
Quadrature Capital Ltd0$00.00%−88,937−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−45,919−100.0%Sold out
LGL Partners, LLC0$00.00%−44,507−100.0%Sold out
Abel Hall, LLC0$00.00%−33,271−100.0%Sold out
Wellington Grp LLC0$00.00%−30,000−100.0%Sold out
Mirabella Financial Services LLP0$00.00%−24,906−100.0%Sold out
Zacks Investment Management0$00.00%−24,665−100.0%Sold out
Capital Advisors Inc0$00.00%−20,000−100.0%Sold out
Principal Financial Group Inc0$00.00%−17,740−100.0%Sold out
CIBC World Markets Inc.0$00.00%−17,228−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−17,036−100.0%Sold out
Sequoia Financial Advisors, LLC0$00.00%−16,264−100.0%Sold out
Stifel Financial Corp0$00.00%−15,549−100.0%Sold out
Moody National Bank Trust Division0$00.00%−13,554−100.0%Sold out
IMC-Chicago, LLC0$00.00%−10,874−100.0%Sold out
Frec Markets, Inc.0$00.00%−10,542−100.0%Sold out
Sanibel Captiva Trust Company, Inc.0$00.00%−10,000−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−4,166−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−806−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−272−100.0%Sold out
Root Financial Partners, LLC0$00.00%−100−100.0%Sold out
MAI Capital Management0$00.00%−43−100.0%Sold out
Darwin Advisors, LLC0$00.00%−5−100.0%Sold out
Wilkerson Advisory Group LLC0$00.00%−4−100.0%Sold out
Janus Henderson Group PLC––––Not filed
U.S. Capital Wealth Advisors, LLC––––Not filed
CWM, LLC––––Not filed
Mill Creek Capital Advisors, LLC––––Not filed
First Affirmative Financial Network––––Not filed
Sunbelt Securities, Inc.––––Not filed