Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Opko Health, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- −8 vs. Q1 2026
- Shares held
- 202.4M
- +1.61M (+0.8%) vs. Q1 2026
- Total value
- $303.4M
- +$74.5M (+32.5%) vs. Q1 2026
- New holders
- 23
- 74 more added
- Sold out
- 31
- 52 more reduced
6 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| RSM US Wealth Management LLC | 31,474 | $47.2K | 0.00% | −2,283−6.8% | Reduced |
| Ameritas Investment Partners, Inc. | 31,889 | $47.8K | 0.00% | 00.0% | Unchanged |
| Operose Advisors LLC | 32,000 | $48.0K | 0.01% | 00.0% | Unchanged |
| Warren Averett Asset Management, LLC | 34,330 | $51.5K | 0.00% | +1,774+5.4% | Added |
| Altshuler Shaham Ltd | 35,992 | $53.7K | 0.00% | +21,217+143.6% | Added |
| The PNC Financial Services Group, Inc. | 37,000 | $55.5K | 0.00% | 00.0% | Unchanged |
| Xponance, Inc. | 38,748 | $58.1K | 0.00% | +1,454+3.9% | Added |
| STRS Ohio | 38,900 | $58.4K | 0.00% | +7,000+21.9% | Added |
| Caitong International Asset Management Co., Ltd | 39,868 | $59.8K | 0.01% | +39,035+4,686.1% | Added |
| Hollencrest Capital Management | 40,000 | $60.0K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 41,591 | $62.4K | 0.00% | +41,591 | New |
| Brighton Jones LLC | 43,153 | $64.7K | 0.00% | +5,203+13.7% | Added |
| Victory Capital Management Inc | 43,623 | $65.4K | 0.00% | −645−1.5% | Reduced |
| Farmers National Bank | 50,300 | $75.5K | 0.02% | 00.0% | Unchanged |
| Mariner, LLC | 50,486 | $75.7K | 0.00% | +11,140+28.3% | Added |
| Group One Trading, L.P. | 50,547 | $75.8K | 0.00% | +9,885+24.3% | Added |
| State of Wisconsin Investment Board | 51,523 | $77.3K | 0.00% | +16,809+48.4% | Added |
| Transcend Wealth Collective, LLC | 51,850 | $77.8K | 0.01% | −55−0.1% | Reduced |
| First Manhattan Co | 52,150 | $78.2K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 52,766 | $79.1K | 0.00% | −87,892−62.5% | Reduced |
| Great West Life Assurance Co | 54,068 | $81.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $82.7K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 55,301 | $83.0K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 57,528 | $86.3K | 0.00% | −32,204−35.9% | Reduced |
| Kestra Private Wealth Services, LLC | 58,450 | $87.7K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 60,947 | $91.4K | 0.00% | +1,595+2.7% | Added |
| Public Employees Retirement Association of Colorado | 61,502 | $92.0K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 63,704 | $95.6K | 0.00% | +23,398+58.1% | Added |
| Pictet Asset Management Holding SA | 65,495 | $98.2K | 0.00% | 00.0% | Unchanged |
| Cascade Financial Partners, LLC | 66,490 | $99.7K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 68,976 | $103.5K | 0.00% | +3,420+5.2% | Added |
| Advisor Group Holdings, Inc. | 69,567 | $104.3K | 0.00% | +21,900+45.9% | Added |
| Millennium Management LLC | 72,301 | $108.5K | 0.00% | +72,301 | New |
| Wealth Enhancement Advisory Services, LLC | 83,994 | $113.4K | 0.00% | +21,629+34.7% | Added |
| Mercer Global Advisors Inc | 76,808 | $115.2K | 0.00% | +23,976+45.4% | Added |
| Cambridge Investment Research Advisors, Inc. | 83,675 | $126.0K | 0.00% | −6,604−7.3% | Reduced |
| Allied Private Wealth LLC | 91,137 | $128.5K | 0.08% | +91,137 | New |
| Intech Investment Management LLC | 85,883 | $128.8K | 0.00% | −39,931−31.7% | Reduced |
| RPg Family Wealth Advisory, LLC | 88,619 | $132.9K | 0.02% | 00.0% | Unchanged |
| KLP Kapitalforvaltning AS | 90,700 | $136.1K | 0.00% | 00.0% | Unchanged |
| Cerity Partners LLC | 91,099 | $136.7K | 0.00% | +67,628+288.1% | Added |
| SRS Capital Advisors, Inc. | 93,616 | $140.4K | 0.00% | +93,323+31,850.9% | Added |
| Ameriprise Financial Inc | 94,061 | $141.1K | 0.00% | −2,661−2.8% | Reduced |
| Barclays PLC | 99,596 | $149.4K | 0.00% | −38,704−28.0% | Reduced |
| Zazove Associates LLC | 100,000 | $150.0K | 0.01% | −200,000−66.7% | Reduced |
| Arizona State Retirement System | 104,725 | $157.1K | 0.00% | −11,253−9.7% | Reduced |
| Headlands Technologies LLC | 107,989 | $162.0K | 0.02% | +51,509+91.2% | Added |
| Vanguard Investments Australia, Ltd. | 110,958 | $166.4K | 0.00% | 00.0% | Unchanged |
| Glenmede Trust Co NA | 112,750 | $169.1K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 113,848 | $171.0K | 0.00% | +26,002+29.6% | Added |
| New York State Common Retirement Fund | 114,301 | $171.5K | 0.00% | 00.0% | Unchanged |
| State of Wyoming | 116,489 | $174.7K | 0.02% | −50,531−30.3% | Reduced |
| Highline Wealth Partners LLC | 116,680 | $175.0K | 0.04% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 119,132 | $178.7K | 0.00% | −2,996−2.5% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 132,463 | $198.7K | 0.00% | +30,066+29.4% | Added |
| Teton Advisors, LLC | 140,000 | $210.0K | 0.12% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 145,234 | $217.9K | 0.00% | +51,899+55.6% | Added |
| 360 Financial, Inc. | 150,300 | $225.4K | 0.06% | +53,000+54.5% | Added |
| Ieq Capital, LLC | 169,425 | $254.1K | 0.00% | +76,203+81.7% | Added |
| JPMorgan Chase & Co | 168,305 | $254.1K | 0.00% | −340,179−66.9% | Reduced |
| Gabelli Funds LLC | 170,000 | $255.0K | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 170,000 | $255.0K | 0.00% | +41,209+32.0% | Added |
| Gamco Investors, Inc. Et Al | 175,000 | $262.5K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 175,801 | $263.7K | 0.00% | +5,801+3.4% | Added |
| State Board of Administration of Florida Retirement System | 176,260 | $264.4K | 0.00% | 00.0% | Unchanged |
| Vanguard Global Advisers, LLC | 181,766 | $272.6K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 185,564 | $278.3K | 0.00% | −12,342−6.2% | Reduced |
| HSBC Holdings PLC | 199,966 | $298.9K | 0.00% | −38,315−16.1% | Reduced |
| Citigroup Inc | 199,824 | $299.7K | 0.00% | +166,148+493.4% | Added |
| Jupiter Topco LLC | 206,314 | $310.5K | 0.00% | +206,314 | New |
| Russell Investments Group, Ltd. | 215,820 | $323.7K | 0.00% | +184,004+578.3% | Added |
| MetLife Investment Management | 226,799 | $340.2K | 0.00% | +22,061+10.8% | Added |
| Jane Street Group, LLC | 229,454 | $344.2K | 0.00% | −884,921−79.4% | Reduced |
| Tudor Investment Corp Et Al | 244,821 | $367.2K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 246,065 | $369.1K | 0.00% | +69,080+39.0% | Added |
| Assenagon Asset Management S.A. | 285,339 | $425.5K | 0.00% | −366,727−56.2% | Reduced |
| XTX Topco Ltd | 286,173 | $429.3K | 0.01% | −144,793−33.6% | Reduced |
| Royal Bank of Canada | 289,812 | $435.0K | 0.00% | +69,818+31.7% | Added |
| Vanguard Asset Management, Ltd | 294,013 | $441.0K | 0.00% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 442,680 | $504.7K | 0.00% | +19,490+4.6% | Added |
| Legal & General Group Plc | 346,787 | $520.2K | 0.00% | +3,313+1.0% | Added |
| Wells Fargo & Company | 354,039 | $531.1K | 0.00% | +191,430+117.7% | Added |
| Algert Global LLC | 397,030 | $595.5K | 0.01% | +397,030 | New |
| Deutsche Bank AG | 398,603 | $597.9K | 0.00% | +27,655+7.5% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 412,051 | $618.1K | 0.00% | −110,855−21.2% | Reduced |
| Commonwealth Equity Services, LLC | 431,894 | $647.8K | 0.00% | +988+0.2% | Added |
| Van Eck Associates Corp | 438,645 | $658.0K | 0.00% | +278,549+174.0% | Added |
| Price T Rowe Associates Inc | 455,748 | $684.0K | 0.00% | +51,096+12.6% | Added |
| Rhumbline Advisers | 498,861 | $748.3K | 0.00% | +1,621+0.3% | Added |
| Kovack Advisors, Inc. | 536,202 | $804.3K | 0.04% | +76,502+16.6% | Added |
| UBS Asset Management Americas Inc | 574,107 | $861.2K | 0.00% | −100,741−14.9% | Reduced |
| PFG Investments, LLC | 610,491 | $915.7K | 0.04% | −502,285−45.1% | Reduced |
| Susquehanna International Group, LLP | 623,561 | $935.3K | 0.00% | +232,045+59.3% | Added |
| Invesco Ltd. | 685,076 | $1.03M | 0.00% | −108,093−13.6% | Reduced |
| Swiss National Bank | 761,455 | $1.14M | 0.00% | −84,300−10.0% | Reduced |
| Bank of America Corp | 795,716 | $1.19M | 0.00% | −346,133−30.3% | Reduced |
| Nuveen, LLC | 863,035 | $1.29M | 0.00% | +16,042+1.9% | Added |
| Clearstead Advisors, LLC | 883,288 | $1.32M | 0.01% | −831−0.1% | Reduced |
| California State Teachers Retirement System | 961,484 | $1.44M | 0.00% | +547,447+132.2% | Added |
| Voya Investment Management LLC | 1,094,111 | $1.64M | 0.00% | −66,816−5.8% | Reduced |