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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Opko Health, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
−31 vs. Q1 2025
Shares held
205.2M
−36.9M (−15.2%) vs. Q1 2025
Total value
$270.4M
−$130.9M (−32.6%) vs. Q1 2025
New holders
17
56 more added
Sold out
48
66 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 222 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ2 2025: $270.4M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2025.

Institutions holding OPK in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Washington Growth Strategies LLC1,356,124$1.79M1.37%+1,356,122+67,806,100.0%Added
Invesco Ltd.1,371,045$1.81M0.00%−252,555−15.6%Reduced
Jane Street Group, LLC1,384,552$1.83M0.00%+835,214+152.0%Added
Y.D. More Investments Ltd1,528,899$2.01M0.14%−244,048−13.8%Reduced
Whitefort Capital Management, LP1,774,200$2.34M0.91%+1,774,200New
Two Sigma Investments, LP1,836,747$2.42M0.00%+190,972+11.6%Added
Bank of America Corp1,906,839$2.52M0.00%−2,252,043−54.2%Reduced
Graham Capital Management, L.P.1,911,131$2.52M0.08%+100,739+5.6%Added
Dimensional Fund Advisors LP1,929,683$2.55M0.00%−292,829−13.2%Reduced
AWM Investment Company, Inc.2,000,000$2.64M0.30%+150,000+8.1%Added
Morgan Stanley2,059,054$2.72M0.00%−2,049,434−49.9%Reduced
Goldman Sachs Group Inc2,820,055$3.72M0.00%−1,181,159−29.5%Reduced
Marshall Wace, LLP3,348,166$4.42M0.01%−1,548,262−31.6%Reduced
Charles Schwab Investment Management Inc3,350,376$4.42M0.00%+608,390+22.2%Added
Northern Trust Corp3,482,272$4.60M0.00%−47,120−1.3%Reduced
Weiss Asset Management LP4,756,992$6.28M0.10%−6,435,808−57.5%Reduced
UBS Group AG5,719,632$7.55M0.00%+3,302,579+136.6%Added
State Street Corp8,581,840$11.3M0.00%+442,344+5.4%Added
Geode Capital Management, LLC10,424,473$13.8M0.00%+1,995,633+23.7%Added
BlackRock, Inc.31,449,482$41.5M0.00%+3,844,508+13.9%Added
Vanguard Group Inc38,238,714$50.5M0.00%+8,738,643+29.6%Added
Rubric Capital Management LP47,791,243$63.1M1.01%−915,397−1.9%Reduced
Sculptor Capital LP0$00.00%−12,717,400−100.0%Sold out
Deerfield Management Company, L.P. (Series C)0$00.00%−6,906,362−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−4,731,688−100.0%Sold out
Lazard Asset Management LLC0$00.00%−3,609,314−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−1,343,701−100.0%Sold out
HRT Financial LP0$00.00%−880,240−100.0%Sold out
Exchange Traded Concepts, LLC0$00.00%−338,948−100.0%Sold out
Quantbot Technologies LP0$00.00%−210,079−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−209,300−100.0%Sold out
Capula Management Ltd0$00.00%−182,512−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−156,247−100.0%Sold out
Numerai GP LLC0$00.00%−133,187−100.0%Sold out
American Century Companies Inc0$00.00%−92,785−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−84,196−100.0%Sold out
Caxton Associates LLP0$00.00%−78,128−100.0%Sold out
Quadrature Capital Ltd0$00.00%−77,658−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−75,647−100.0%Sold out
Group One Trading, L.P.0$00.00%−50,794−100.0%Sold out
Jump Financial, LLC0$00.00%−49,070−100.0%Sold out
Inspire Advisors, LLC0$00.00%−47,130−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−45,966−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−28,907−100.0%Sold out
Voleon Capital Management LP0$00.00%−27,225−100.0%Sold out
Pallas Capital Advisors LLC0$00.00%−25,851−100.0%Sold out
Jain Global LLC0$00.00%−24,200−100.0%Sold out
Toroso Investments, LLC0$00.00%−23,618−100.0%Sold out
Cerity Partners LLC0$00.00%−21,528−100.0%Sold out
N.E.W. Advisory Services LLC0$00.00%−20,075−100.0%Sold out
GM Advisory Group, Inc.0$00.00%−20,000−100.0%Sold out
C2C Wealth Management, LLC0$00.00%−16,405−100.0%Sold out
Oak Thistle LLC0$00.00%−15,636−100.0%Sold out
Abel Hall, LLC0$00.00%−14,170−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−13,870−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−13,100−100.0%Sold out
Canada Pension Plan Investment Board0$00.00%−12,900−100.0%Sold out
R Squared Ltd0$00.00%−12,290−100.0%Sold out
Farringdon Capital, Ltd.0$00.00%−11,834−100.0%Sold out
Colony Group, LLC0$00.00%−11,524−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−11,056−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−10,930−100.0%Sold out
Merit Financial Group, LLC0$00.00%−10,249−100.0%Sold out
Atria Wealth Solutions, Inc.0$00.00%−10,000−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.0$00.00%−6,914−100.0%Sold out
Penserra Capital Management LLC0$00.00%−6,434−100.0%Sold out
Quarry LP0$00.00%−4,706−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−1,820−100.0%Sold out
Grove Bank & Trust0$00.00%−250−100.0%Sold out
Truvestments Capital LLC0$00.00%−100−100.0%Sold out
Orion Portfolio Solutions, LLC––––Not filed
CAPROCK Group, Inc.––––Not filed