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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Opko Health, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
218
−7 vs. Q3 2023
Shares held
169.9M
+2.69M (+1.6%) vs. Q3 2023
Total value
$256.6M
−$11.0M (−4.1%) vs. Q3 2023
New holders
25
53 more added
Sold out
32
65 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 218 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ4 2023: $256.6M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2023.

Institutions holding OPK in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
HighTower Advisors, LLC39,924$60.0K0.00%−4,000−9.1%Reduced
Ameritas Investment Partners, Inc.39,779$60.1K0.00%00.0%Unchanged
Comerica Bank40,000$60.4K0.00%00.0%Unchanged
Cetera Advisor Networks LLC40,195$60.7K0.00%00.0%Unchanged
State of Wisconsin Investment Board40,329$60.9K0.00%−310,594−88.5%Reduced
First Manhattan Co40,525$61.2K0.00%+36,525+913.1%Added
Amundi60,662$63.1K0.00%00.0%Unchanged
Integrated Wealth Concepts LLC44,500$67.2K0.00%00.0%Unchanged
Kestra Private Wealth Services, LLC45,300$68.4K0.00%−700−1.5%Reduced
Ethic Inc.45,681$69.0K0.00%−1,400−3.0%Reduced
Tower Research Capital LLC (TRC)47,320$71.5K0.00%+19,219+68.4%Added
Shell Asset Management Co48,941$74.0K0.00%−14,773−23.2%Reduced
Kestra Advisory Services, LLC50,282$75.9K0.00%+1,000+2.0%Added
Farmers National Bank50,300$76.0K0.02%00.0%Unchanged
Transcend Wealth Collective, LLC50,850$76.8K0.01%00.0%Unchanged
Principal Financial Group Inc51,114$77.2K0.00%−8,452−14.2%Reduced
Raymond James Financial Services Advisors, Inc.51,854$78.3K0.00%−1,000−1.9%Reduced
Captrust Financial Advisors51,966$78.5K0.00%+1,240+2.4%Added
Great West Life Assurance Co54,068$81.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)55,140$83.3K0.00%00.0%Unchanged
Victory Capital Management Inc55,899$84.4K0.00%+10,023+21.8%Added
Public Employees Retirement Association of Colorado61,502$93.0K0.00%00.0%Unchanged
360 Financial, Inc.62,500$94.4K0.04%+7,340+13.3%Added
Pictet Asset Management Holding SA65,495$98.9K0.00%00.0%Unchanged
ProShare Advisors LLC66,766$100.8K0.00%+14,365+27.4%Added
RSM US Wealth Management LLC70,000$105.7K0.00%+70,000New
Qube Research & Technologies Ltd74,259$112.1K0.00%−871−1.2%Reduced
Handelsbanken Fonder AB76,721$116.0K0.00%−9,400−10.9%Reduced
Hollencrest Capital Management78,980$119.3K0.01%−5,000−6.0%Reduced
RPg Family Wealth Advisory, LLC80,330$121.3K0.04%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)80,348$121.3K0.00%+80,348New
State of Wyoming82,890$125.2K0.02%−4,627−5.3%Reduced
Verition Fund Management LLC99,798$150.7K0.00%−49,753−33.3%Reduced
Intrepid Capital Management Inc100,000$151.0K0.10%00.0%Unchanged
Prudential Financial Inc104,996$158.5K0.00%−235−0.2%Reduced
Advisor Group Holdings, Inc.106,676$161.1K0.00%−22,177−17.2%Reduced
Blair William & Co109,786$165.8K0.00%00.0%Unchanged
Ameriprise Financial Inc110,691$167.1K0.00%−138,118−55.5%Reduced
Cambridge Investment Research Advisors, Inc.116,239$176.0K0.00%+290+0.3%Added
Highline Wealth Partners LLC116,680$176.2K0.09%00.0%Unchanged
Csenge Advisory Group117,000$176.7K0.01%00.0%Unchanged
Arizona State Retirement System118,857$179.5K0.00%−2,142−1.8%Reduced
New York State Common Retirement Fund127,900$193.1K0.00%00.0%Unchanged
Wilbanks Smith & Thomas Asset Management LLC131,380$198.4K0.01%00.0%Unchanged
Van Eck Associates Corp132,935$201.0K0.00%−17,836−11.8%Reduced
Parallax Volatility Advisers, L.P.134,280$202.8K0.01%+134,280New
Simplex Trading, LLC148,360$224.0K0.01%+148,360New
POM Investment Strategies, LLC158,053$238.7K0.22%+158,053New
Teton Advisors, Inc.170,000$256.7K0.08%−8,000−4.5%Reduced
State Board of Administration of Florida Retirement System176,260$266.2K0.00%00.0%Unchanged
X-Square Capital, LLC177,900$269.0K0.15%−2,170−1.2%Reduced
Gabelli Funds LLC181,000$273.3K0.00%00.0%Unchanged
Gamco Investors, Inc. Et Al185,000$279.4K0.00%−15,000−7.5%Reduced
Wells Fargo & Company185,805$280.6K0.00%+14,682+8.6%Added
Franklin Resources Inc193,867$292.7K0.00%00.0%Unchanged
American International Group, Inc.200,496$302.7K0.00%−810−0.4%Reduced
Janus Henderson Group PLC208,449$313.7K0.00%−345−0.2%Reduced
MetLife Investment Management211,348$319.1K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The234,887$354.7K0.00%−6,330−2.6%Reduced
Graham Capital Management, L.P.235,604$355.8K0.01%+47,543+25.3%Added
SG Americas Securities, LLC244,294$369.0K0.00%+39,459+19.3%Added
Tudor Investment Corp Et Al244,821$369.7K0.01%00.0%Unchanged
ExodusPoint Capital Management, LP265,830$401.0K0.00%+253,741+2,098.9%Added
BNP Paribas Arbitrage, SA271,872$410.5K0.00%+211,429+349.8%Added
American Century Companies Inc276,664$417.8K0.00%−1,008−0.4%Reduced
Royal Bank of Canada304,411$460.0K0.00%+50,248+19.8%Added
First Trust Advisors LP305,731$461.7K0.00%+305,731New
Group One Trading, L.P.308,615$466.0K0.01%+308,615New
Engineers Gate Manager LP320,419$483.8K0.01%−27,107−7.8%Reduced
AQR Capital Management LLC326,655$493.2K0.00%+151,025+86.0%Added
HRT Financial LP343,605$518.0K0.00%+89,275+35.1%Added
Jane Street Group, LLC358,144$540.8K0.00%+216,369+152.6%Added
UBS Asset Management Americas Inc401,189$605.8K0.00%00.0%Unchanged
Bank of America Corp408,055$616.2K0.00%+117,161+40.3%Added
Citadel Advisors LLC408,551$616.9K0.00%+198,960+94.9%Added
Commonwealth Equity Services, LLC412,926$624.0K0.00%−1,943−0.5%Reduced
Legal & General Group Plc418,602$632.1K0.00%00.0%Unchanged
Price T Rowe Associates Inc428,310$647.0K0.00%+29,117+7.3%Added
California State Teachers Retirement System444,922$671.8K0.00%−19,639−4.2%Reduced
Marshall Wace, LLP465,493$702.9K0.00%−99,040−17.5%Reduced
Susquehanna International Group, LLP496,397$749.6K0.00%+342,832+223.2%Added
Alps Advisors Inc536,481$810.1K0.01%+536,481New
Alliancebernstein L.P.570,109$860.9K0.00%−20,130−3.4%Reduced
Millennium Management LLC596,444$900.6K0.00%−516,842−46.4%Reduced
Assenagon Asset Management S.A.605,239$959.7K0.00%−254,100−29.6%Reduced
Rhumbline Advisers650,017$981.5K0.00%+1,132+0.2%Added
Hennion & Walsh Asset Management, Inc.696,495$1.05M0.06%+28,975+4.3%Added
Weiss Multi-Strategy Advisers LLC700,000$1.06M0.03%+700,000New
Allianz Asset Management GmbH764,209$1.15M0.00%+263,389+52.6%Added
Jupiter Asset Management Ltd765,198$1.16M0.01%00.0%Unchanged
Barclays PLC768,078$1.16M0.00%+579,657+307.6%Added
Swiss National Bank837,855$1.27M0.00%−96,200−10.3%Reduced
Credit Suisse AG896,018$1.35M0.00%+260,379+41.0%Added
Deutsche Bank AG951,120$1.44M0.00%+722,249+315.6%Added
Two Sigma Investments, LP968,815$1.46M0.00%−471,367−32.7%Reduced
Intrinsic Edge Capital Management LLC1,000,000$1.51M0.16%+100,000+11.1%Added
AWM Investment Company, Inc.1,100,000$1.66M0.22%+100,000+10.0%Added
Two Sigma Advisers, LP1,136,897$1.72M0.00%−176,200−13.4%Reduced
Nuveen Asset Management, LLC1,147,369$1.73M0.00%−1,517,045−56.9%Reduced
UBS Group AG1,413,300$2.13M0.00%+399,290+39.4%Added