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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Opko Health, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
229
−5 vs. Q4 2021
Shares held
195.0M
+4.82M (+2.5%) vs. Q4 2021
Total value
$671.0M
−$243.7M (−26.6%) vs. Q4 2021
New holders
35
54 more added
Sold out
40
73 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 229 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ1 2022: $671.0M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2021.

Institutions holding OPK in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Alps Advisors Inc700,368$2.41M0.03%−88,162−11.2%Reduced
Jupiter Asset Management Ltd788,416$2.70M0.03%00.0%Unchanged
AWM Investment Company, Inc.800,000$2.75M0.35%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.801,974$2.76M0.15%−40,352−4.8%Reduced
UBS Group AG879,386$3.03M0.00%+157,935+21.9%Added
Swiss National Bank1,047,200$3.60M0.00%+72,900+7.5%Added
Susquehanna International Group, LLP1,214,277$4.18M0.01%−2,759,565−69.4%Reduced
Phoenix Holdings Ltd.1,328,562$4.57M0.08%+1,328,562New
Nordea Investment Management AB1,329,997$4.71M0.01%+9,908+0.8%Added
Rafferty Asset Management, LLC1,639,109$5.64M0.03%+752,379+84.8%Added
Millennium Management LLC1,765,569$6.07M0.01%+1,285,809+268.0%Added
Bank of America Corp1,794,830$6.17M0.00%+1,175,492+189.8%Added
Bank of New York Mellon Corp2,115,948$7.28M0.00%−4,996−0.2%Reduced
Invesco Ltd.2,579,006$8.87M0.00%+2,138,491+485.5%Added
Prudential Financial Inc2,587,076$8.90M0.01%−94,880−3.5%Reduced
Morgan Stanley2,621,574$9.02M0.00%+1,760,173+204.3%Added
JPMorgan Chase & Co2,676,143$9.21M0.00%+463,047+20.9%Added
Goldman Sachs Group Inc3,001,411$10.3M0.00%−858,033−22.2%Reduced
Nuveen Asset Management, LLC3,493,482$12.5M0.00%+1,2720.0%Added
Norges Bank3,832,941$13.2M0.00%−443,442−10.4%Reduced
Charles Schwab Investment Management Inc3,870,903$13.3M0.00%+296,038+8.3%Added
D. E. Shaw & Co., Inc.5,375,226$18.5M0.02%+1,294,225+31.7%Added
Northern Trust Corp5,734,926$19.7M0.00%−500,674−8.0%Reduced
Dimensional Fund Advisors LP7,184,414$24.7M0.01%+3,037,320+73.2%Added
Geode Capital Management, LLC7,767,491$26.7M0.00%+37,079+0.5%Added
Oracle Investment Management Inc8,985,756$30.9M6.22%−3,233,317−26.5%Reduced
State Street Corp27,688,831$95.3M0.00%+10,014,088+56.7%Added
BlackRock Inc.33,870,368$116.5M0.00%−520,544−1.5%Reduced
Vanguard Group Inc36,072,131$124.1M0.00%+346,707+1.0%Added
Connor, Clark & Lunn Investment Management Ltd.0$00.00%−627,454−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−508,967−100.0%Sold out
Toronto Dominion Bank0$00.00%−437,732−100.0%Sold out
Old Mission Capital LLC0$00.00%−412,551−100.0%Sold out
Verition Fund Management LLC0$00.00%−375,702−100.0%Sold out
Susquehanna Fundamental Investments, LLC0$00.00%−356,280−100.0%Sold out
HRT Financial LP0$00.00%−313,544−100.0%Sold out
Intrinsic Edge Capital Management LLC0$00.00%−300,000−100.0%Sold out
Wolverine Asset Management LLC0$00.00%−138,500−100.0%Sold out
Sax Wealth Advisors, LLC0$00.00%−84,110−100.0%Sold out
Bank of Nova Scotia0$00.00%−77,477−100.0%Sold out
Sowell Financial Services LLC0$00.00%−75,200−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−65,604−100.0%Sold out
Cornerstone Investment Partners, LLC0$00.00%−55,500−100.0%Sold out
Walleye Trading LLC0$00.00%−40,680−100.0%Sold out
Gotham Asset Management, LLC0$00.00%−39,488−100.0%Sold out
Twinbeech Capital LP0$00.00%−27,816−100.0%Sold out
Janney Montgomery Scott LLC0$00.00%−25,350−100.0%Sold out
Arkadios Wealth Advisors0$00.00%−25,000−100.0%Sold out
Teamwork Financial Advisors, LLC0$00.00%−23,760−100.0%Sold out
Spire Wealth Management0$00.00%−23,727−100.0%Sold out
Pearl River Capital, LLC0$00.00%−23,314−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−21,276−100.0%Sold out
Allianz Asset Management GmbH0$00.00%−19,990−100.0%Sold out
National Asset Management, Inc.0$00.00%−18,600−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−17,135−100.0%Sold out
Modera Wealth Management, LLC0$00.00%−15,196−100.0%Sold out
Natixis0$00.00%−14,000−100.0%Sold out
Wolverine Trading, LLC0$00.00%−12,699−100.0%Sold out
Gladstone Institutional Advisory LLC0$00.00%−11,622−100.0%Sold out
Russell Investments Group, Ltd.0$00.00%−10,437−100.0%Sold out
Cornerstone Advisory, LLC0$00.00%−6,000−100.0%Sold out
Northwestern Mutual Wealth Management Co0$00.00%−2,500−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−1,600−100.0%Sold out
TCI Wealth Advisors, Inc.0$00.00%−1,374−100.0%Sold out
Eaton Vance Management0$00.00%−1,195−100.0%Sold out
Amplius Wealth Advisors, LLC0$00.00%−1,000−100.0%Sold out
Masso Torrence Wealth Management Inc.0$00.00%−839−100.0%Sold out
Snowden Capital Advisors LLC0$00.00%−300−100.0%Sold out
Burleson & Company, LLC0$00.00%−1−100.0%Sold out
Columbia Asset Management––––Not filed
Harbour Investments, Inc.––––Not filed