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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Opko Health, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
236
+30 vs. Q3 2021
Shares held
190.2M
+6.95M (+3.8%) vs. Q3 2021
Total value
$914.8M
+$246.0M (+36.8%) vs. Q3 2021
New holders
53
58 more added
Sold out
23
63 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 236 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ4 2021: $914.8M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2021.

Institutions holding OPK in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Alliancebernstein L.P.597,900$2.88M0.00%−300,000−33.4%Reduced
Rhumbline Advisers615,881$2.96M0.00%−4,975−0.8%Reduced
Bank of America Corp619,338$2.98M0.00%+399,970+182.3%Added
Connor, Clark & Lunn Investment Management Ltd.627,454$3.02M0.01%−361,676−36.6%Reduced
Wells Fargo & Company685,660$3.30M0.00%−334,792−32.8%Reduced
UBS Group AG721,451$3.47M0.00%−95,826−11.7%Reduced
Citigroup Inc745,733$3.59M0.00%+132,243+21.6%Added
ExodusPoint Capital Management, LP782,145$3.76M0.05%+345,531+79.1%Added
Alps Advisors Inc788,530$3.79M0.04%+788,530New
Jupiter Asset Management Ltd788,416$3.82M0.04%+224,398+39.8%Added
AWM Investment Company, Inc.800,000$3.85M0.39%00.0%Unchanged
Citadel Advisors LLC828,065$3.98M0.00%+616,393+291.2%Added
Hennion & Walsh Asset Management, Inc.842,326$4.05M0.20%−769,741−47.7%Reduced
Morgan Stanley861,401$4.14M0.00%−262,464−23.4%Reduced
Rafferty Asset Management, LLC886,730$4.26M0.02%+16,064+1.8%Added
Swiss National Bank974,300$4.69M0.00%+14,300+1.5%Added
Jane Street Group, LLC1,342,228$6.46M0.01%+863,575+180.4%Added
Nordea Investment Management AB1,320,089$6.53M0.01%−8,753−0.7%Reduced
Bank of New York Mellon Corp2,120,944$10.2M0.00%+166,335+8.5%Added
JPMorgan Chase & Co2,213,096$10.6M0.00%+936,522+73.4%Added
Prudential Financial Inc2,681,956$12.9M0.02%−1,099,863−29.1%Reduced
Nuveen Asset Management, LLC3,492,210$16.8M0.00%+656,465+23.1%Added
Charles Schwab Investment Management Inc3,574,865$17.2M0.01%+24,106+0.7%Added
Goldman Sachs Group Inc3,859,444$18.6M0.00%+1,844,799+91.6%Added
Susquehanna International Group, LLP3,973,842$19.1M0.03%+966,579+32.1%Added
D. E. Shaw & Co., Inc.4,081,001$19.6M0.02%+2,003,147+96.4%Added
Dimensional Fund Advisors LP4,147,094$19.9M0.01%−326,001−7.3%Reduced
Norges Bank4,276,383$20.6M0.00%+1,215,448+39.7%Added
Northern Trust Corp6,235,600$30.0M0.00%−76,350−1.2%Reduced
Point72 Asset Management, L.P.6,654,123$32.0M0.14%+6,654,123New
Geode Capital Management, LLC7,730,412$37.2M0.00%+1,6820.0%Added
Oracle Investment Management Inc12,219,073$58.8M8.63%−600,000−4.7%Reduced
State Street Corp17,674,743$85.0M0.00%−5,699,872−24.4%Reduced
BlackRock Inc.34,390,912$165.4M0.00%−434,768−1.2%Reduced
Vanguard Group Inc35,725,424$171.8M0.00%+259,540+0.7%Added
Castleview Partners, LLC16,835––+16,835New
Renaissance Technologies LLC0$00.00%−910,153−100.0%Sold out
Phoenix Holdings Ltd.0$00.00%−266,862−100.0%Sold out
Ergoteles LLC0$00.00%−113,021−100.0%Sold out
Hussman Strategic Advisors, Inc.0$00.00%−93,000−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−49,641−100.0%Sold out
Pinnacle Associates Ltd0$00.00%−43,975−100.0%Sold out
Susquehanna International Group Ltd.0$00.00%−26,549−100.0%Sold out
Boston Private Wealth LLC0$00.00%−21,770−100.0%Sold out
Two Sigma Investments, LP0$00.00%−17,804−100.0%Sold out
Aries Wealth Management0$00.00%−15,200−100.0%Sold out
Tuttle Tactical Management0$00.00%−11,603−100.0%Sold out
Linscomb & Williams, Inc.0$00.00%−11,000−100.0%Sold out
Eqis Capital Management, Inc.0$00.00%−10,309−100.0%Sold out
Nomura Holdings Inc0$00.00%−6,400−100.0%Sold out
Antonetti Capital Management LLC0$00.00%−4,000−100.0%Sold out
Bank of Montreal0$00.00%−3,588−100.0%Sold out
JNBA Financial Advisors0$00.00%−750−100.0%Sold out
Emfo, LLC0$00.00%−740−100.0%Sold out
Walled Lake Planning & Wealth Management, LLC0$00.00%−500−100.0%Sold out
Newbridge Financial Services Group, Inc.0$00.00%−500−100.0%Sold out
Firestone Capital Management0$00.00%−200−100.0%Sold out
Baystate Wealth Management LLC0$00.00%−99−100.0%Sold out
Jacobi Capital Management LLC0$00.00%−100−100.0%Sold out