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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
422
+57 vs. Q1 2026
Shares held
30.3M
+2.19M (+7.8%) vs. Q1 2026
Total value
$11.1B
+$3.82B (+52.7%) vs. Q1 2026
New holders
93
178 more added
Sold out
36
109 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 422 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2026: $11.1B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2026.

Institutions holding KRYS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Portside Wealth Group, LLC679$252.4K0.03%+679New
Advisory Services Network, LLC674$250.5K0.00%−291−30.2%Reduced
M&T Bank Corp668$247.8K0.00%+668New
Wealth Enhancement Advisory Services, LLC651$238.1K0.00%+651New
GF Fund Management Co. Ltd.620$230.4K0.00%−31−4.8%Reduced
National Bank of Canada617$229.1K0.00%+617New
Concurrent Investment Advisors, LLC616$228.9K0.00%+616New
denkapparat Operations GmbH608$226.0K0.07%+608New
Sage Rhino Capital LLC604$224.5K0.04%+604New
Eurizon Capital SGR S.p.A.587$222.2K0.00%+34+6.1%Added
Alliance Wealth Advisors, LLC586$217.8K0.04%+586New
EJMK Ventures LLC561$208.5K0.09%+561New
Ark Wealth Advisors LLC548$203.7K0.18%+548New
Peregrine Asset Advisers, Inc.547$203.3K0.04%+547New
Global Retirement Partners, LLC519$192.9K0.00%+519New
Covestor Ltd493$183.0K0.11%+193+64.3%Added
Allworth Financial LP469$174.3K0.00%+421+877.1%Added
Hantz Financial Services, Inc.465$173.0K0.00%−9−1.9%Reduced
Advisors Asset Management, Inc.422$156.8K0.00%+130+44.5%Added
Bryn Mawr Trust Co393$146.1K0.00%00.0%Unchanged
Horizon Investments, LLC342$127.1K0.00%+38+12.5%Added
Smartleaf Asset Management LLC308$116.5K0.00%00.0%Unchanged
Quantbot Technologies LP305$113.4K0.00%+172+129.3%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.299$111.1K0.00%−56−15.8%Reduced
USA Financial Formulas269$100.0K0.02%+269New
SRS Capital Advisors, Inc.268$99.6K0.00%+264+6,600.0%Added
US Bancorp251$93.3K0.00%+17+7.3%Added
Caldwell Trust Co250$92.9K0.01%00.0%Unchanged
Harbor Investment Advisory, LLC247$91.8K0.01%+247New
Kemnay Advisory Services Inc.232$86.2K0.01%+16+7.4%Added
Salomon & Ludwin, LLC227$84.3K0.01%+26+12.9%Added
Acadian Asset Management LLC218$81.0K0.00%+218New
Rockefeller Capital Management L.P.217$80.7K0.00%−14−6.1%Reduced
Versant Capital Management, Inc214$79.5K0.01%+140+189.2%Added
Concord Wealth Partners213$79.1K0.01%+213New
Optiver Holding B.V.211$78.4K0.00%+211New
Huntington National Bank193$71.7K0.00%+10+5.5%Added
Umb Bank N A172$63.9K0.00%+21+13.9%Added
AdvisorNet Financial, Inc171$63.6K0.00%00.0%Unchanged
Key Financial Inc151$56.1K0.01%00.0%Unchanged
Signaturefd, LLC132$49.1K0.00%+27+25.7%Added
Bernard Wealth Management Corp.130$48.3K0.02%+130New
SBI Securities Co., Ltd.123$45.7K0.00%+54+78.3%Added
Los Angeles Capital Management LLC118$43.9K0.00%−2,053−94.6%Reduced
Bayforest Capital Ltd106$39.4K0.04%+106New
Reyes Financial Architecture, Inc.100$37.2K0.02%00.0%Unchanged
Toronto Dominion Bank96$35.7K0.00%+96New
Basecamp Wealth Advisors LLC94$34.9K0.01%+9+10.6%Added
Sterling Capital Management LLC91$33.8K0.00%−70−43.5%Reduced
Massmutual Trust Co FSB90$33.5K0.00%+4+4.7%Added
Farther Finance Advisors, LLC83$30.9K0.00%+28+50.9%Added
EverSource Wealth Advisors, LLC82$30.5K0.00%−26−24.1%Reduced
Silvant Capital Management LLC80$29.7K0.00%+80New
E Fund Management (Hong Kong) Co., Ltd.77$28.6K0.01%+20+35.1%Added
Bare Financial Services, Inc72$26.8K0.01%+25+53.2%Added
IFP Advisors, Inc55$20.4K0.00%−10−15.4%Reduced
Private Wealth Management Group, LLC55$20.4K0.00%00.0%Unchanged
SMA Capital LLC55$20.4K0.01%+55New
Rialto Wealth Management, LLC52$19.3K0.00%+51+5,100.0%Added
Westside Investment Management, Inc.50$18.6K0.00%+15+42.9%Added
Parkside Financial Bank & Trust49$18.2K0.00%+15+44.1%Added
Persistent Asset Partners Ltd49$18.2K0.01%+49New
Harbour Investments, Inc.39$14.5K0.00%+6+18.2%Added
Keating Financial Advisory Services, Inc.39$14.5K0.00%+11+39.3%Added
GWM Advisors LLC34$12.8K0.00%−3−8.1%Reduced
Quent Capital, LLC34$12.6K0.00%00.0%Unchanged
Rothschild Investment LLC33$12.3K0.00%+5+17.9%Added
Accent Capital Management, LLC31$11.5K0.00%+31New
Fulcrum Asset Management LLP28$10.6K0.00%+28New
Acumen Wealth Advisors, LLC27$10.0K0.00%−7−20.6%Reduced
Larson Financial Group LLC27$10.0K0.00%+11+68.8%Added
Caitong International Asset Management Co., Ltd27$10.0K0.00%+27New
Rakuten Securities, Inc.21$7.80K0.00%+21New
Trust Co of Vermont20$7.43K0.00%+20New
Zions Bancorporation, National Association17$6.32K0.00%+5+41.7%Added
Truvestments Capital LLC17$6.32K0.00%+17New
Bell Investment Advisors, Inc16$5.95K0.00%00.0%Unchanged
Farmers & Merchants Investments Inc15$5.58K0.00%00.0%Unchanged
IMA Wealth, Inc.15$5.58K0.00%+5+50.0%Added
CVA Family Office, LLC15$5.58K0.00%+12+400.0%Added
Cornerstone Financial Management LLC14$5.20K0.00%00.0%Unchanged
Colonial Trust Co14$5.20K0.00%+6+75.0%Added
Fortitude Family Office, LLC13$4.83K0.00%+2+18.2%Added
JFS Wealth Advisors, LLC12$4.46K0.00%+7+140.0%Added
Walleye Capital LLC12$4.46K0.00%−342−96.6%Reduced
Clearstead Advisors, LLC11$4.09K0.00%+11New
JPL Wealth Management, LLC10$3.72K0.00%00.0%Unchanged
Aspect Partners, LLC10$3.72K0.00%+10New
Hughes Financial Services, LLC9$3.35K0.00%+4+80.0%Added
Retirement Wealth Solutions LLC8$2.97K0.00%00.0%Unchanged
International Assets Investment Management, LLC8$2.97K0.00%+4+100.0%Added
Dogwood Wealth Management LLC7$2.60K0.00%+7New
Action Point Financial Planning, LLC6$2.23K0.00%+6New
Plante Moran Financial Advisors, LLC6$2.23K0.00%+6New
Avion Wealth6$2.00K0.00%00.0%Unchanged
UMA Financial Services, Inc.5$1.86K0.00%+1+25.0%Added
Salem Investment Counselors Inc5$1.86K0.00%+5New
Glen Eagle Advisors, LLC5$1.86K0.00%00.0%Unchanged
Private Trust Co NA5$1.86K0.00%+5New
Cape Investment Advisory, Inc.5$1.86K0.00%+5New