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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
422
+57 vs. Q1 2026
Shares held
30.3M
+2.19M (+7.8%) vs. Q1 2026
Total value
$11.1B
+$3.82B (+52.7%) vs. Q1 2026
New holders
93
178 more added
Sold out
36
109 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 422 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2026: $11.1B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2026.

Institutions holding KRYS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Teacher Retirement System of Texas2,414$897.2K0.00%−409−14.5%Reduced
RMB Capital Management, LLC2,400$892.0K0.01%+2,400New
Pier 88 Investment Partners LLC2,400$892.0K0.21%−1,100−31.4%Reduced
Blair William & Co2,397$890.9K0.00%−51−2.1%Reduced
Ameritas Investment Partners, Inc.2,372$881.6K0.02%+317+15.4%Added
Public Employees Retirement Association of Colorado2,363$878.0K0.00%00.0%Unchanged
Empowered Funds, LLC2,325$864.1K0.00%+49+2.2%Added
Janney Montgomery Scott LLC2,309$858.0K0.00%+139+6.4%Added
Crossmark Global Holdings, Inc.2,186$812.5K0.01%−108−4.7%Reduced
Summit Global Investments2,167$805.0K0.04%+2,167New
Ballentine Partners, LLC2,138$794.6K0.01%+23+1.1%Added
Swiss Life Asset Management Ltd2,136$793.9K0.00%−29−1.3%Reduced
HighTower Advisors, LLC2,129$791.3K0.00%+80+3.9%Added
Alps Advisors Inc2,035$756.3K0.00%+35+1.8%Added
Yorktown Management & Research Co Inc2,000$743.3K0.46%00.0%Unchanged
Royal Bank of Canada1,961$728.0K0.00%+928+89.8%Added
Vident Advisory, LLC1,956$727.0K0.01%+342+21.2%Added
AlphaCentric Advisors LLC1,945$722.9K0.61%+27+1.4%Added
Cerity Partners LLC1,899$705.9K0.00%+1,899New
Susquehanna International Group, LLP1,899$705.8K0.00%−7,143−79.0%Reduced
Measured Wealth Private Client Group, LLC1,887$701.3K0.17%+61+3.3%Added
Baader Bank INC1,800$669.0K0.05%+1,800New
Seven Fleet Capital Management LP1,774$659.3K0.11%−2,542−58.9%Reduced
Truist Financial Corp1,773$659.0K0.00%+609+52.3%Added
Vise Technologies, Inc.1,762$654.9K0.01%+338+23.7%Added
Federation des caisses Desjardins du Quebec1,733$644.1K0.00%+1,683+3,366.0%Added
O'Shaughnessy Asset Management, LLC1,708$634.8K0.00%−115−6.3%Reduced
Optimize Financial Inc1,705$633.7K0.23%−5−0.3%Reduced
Sound Capital Solutions LLC1,705$633.7K0.15%+1,705New
Parallel Advisors, LLC1,699$631.5K0.01%+11+0.7%Added
CIBC Bancorp USA Inc.1,680$624.4K0.00%+415+32.8%Added
Gsa Capital Partners LLP1,643$611.0K0.04%+1,643New
Mindset Wealth Management, LLC1,600$594.7K0.11%+150+10.3%Added
Tower Research Capital LLC (TRC)1,585$589.1K0.01%−733−31.6%Reduced
Bokf, NA1,573$584.6K0.01%−256−14.0%Reduced
Sound View Wealth Advisors Group, LLC1,519$564.6K0.04%−75−4.7%Reduced
QRG Capital Management, Inc.1,501$557.9K0.00%+220+17.2%Added
Greenwood Capital Associates LLC1,495$555.6K0.05%+661+79.3%Added
Captrust Financial Advisors1,448$538.2K0.00%+269+22.8%Added
Argent Trust Co1,426$530.0K0.02%+165+13.1%Added
Vontobel Holding Ltd.1,402$521.1K0.00%−716−33.8%Reduced
Allstate Corp1,389$516.3K0.01%−3,044−68.7%Reduced
Stratos Wealth Partners, LTD.1,382$513.6K0.01%−77−5.3%Reduced
Jones Financial Companies LLLP1,380$513.6K0.00%+725+110.7%Added
Ensign Peak Advisors, Inc1,369$508.8K0.00%00.0%Unchanged
Aviva PLC1,355$503.6K0.00%−336−19.9%Reduced
Gotham Asset Management, LLC1,330$494.3K0.00%+7+0.5%Added
E Fund Management Co., Ltd.1,323$491.7K0.01%−958−42.0%Reduced
Mirae Asset Global Investments Co., Ltd.1,318$489.9K0.00%−207−13.6%Reduced
Pacer Advisors, Inc.1,315$489.0K0.00%−1,232−48.4%Reduced
Vestcor Inc1,311$487.0K0.01%00.0%Unchanged
Diversify Advisory Services, LLC1,373$483.0K0.01%+1,373New
Diversify Wealth Management, LLC1,373$483.0K0.01%+1,373New
Hidden Cove Wealth Management, LLC1,220$453.4K0.25%−82−6.3%Reduced
DnB Asset Management AS1,211$450.1K0.00%−1,889−60.9%Reduced
Nisa Investment Advisors, LLC1,211$450.1K0.00%+274+29.2%Added
Net Worth Advisory Group1,207$448.8K0.11%−100−7.7%Reduced
Ethic Inc.1,206$448.4K0.01%+40+3.4%Added
Mount Yale Investment Advisors, LLC1,204$447.5K0.01%+74+6.5%Added
Nykredit A/S1,178$437.8K0.00%+1,178New
New Age Alpha Advisors, LLC1,152$428.2K0.02%−50−4.2%Reduced
Evergreen Capital Management LLC1,124$417.8K0.01%+30+2.7%Added
XTX Topco Ltd1,121$416.6K0.01%−6,358−85.0%Reduced
Fifth Third Wealth Advisors LLC1,109$412.2K0.01%+90+8.8%Added
Mariner, LLC1,079$401.0K0.00%+31+3.0%Added
Linden Thomas Advisory Services, LLC1,064$395.5K0.03%−8−0.7%Reduced
Hohimer Wealth Management, LLC1,038$385.8K0.04%+4+0.4%Added
MAI Capital Management1,035$384.7K0.00%+25+2.5%Added
Welch Group, LLC1,000$371.7K0.01%00.0%Unchanged
GAMMA Investing LLC998$370.9K0.01%+140+16.3%Added
Toroso Investments, LLC989$367.6K0.00%−99−9.1%Reduced
Roman Butler Fullerton & Co1,009$366.7K0.09%+1,009New
Inspire Advisors, LLC958$355.9K0.02%+958New
Jane Street Group, LLC956$355.3K0.00%+956New
NLB Skladi, upravljanje premozenja, d.o.o.955$354.9K0.01%00.0%Unchanged
RSM US Wealth Management LLC935$347.5K0.00%+83+9.7%Added
Kingswood Wealth Advisors, LLC926$344.2K0.01%−464−33.4%Reduced
Sequoia Financial Advisors, LLC923$343.1K0.00%−70−7.0%Reduced
Freestone Grove Partners LP920$341.9K0.00%−2,002−68.5%Reduced
Hennion & Walsh Asset Management, Inc.906$336.7K0.01%+906New
Everence Capital Management Inc892$332.0K0.02%+92+11.5%Added
Total Clarity Wealth Management, Inc.890$330.8K0.06%+890New
CIBC Asset Management Inc888$330.0K0.00%00.0%Unchanged
Brinker Capital Investments, LLC887$329.6K0.00%+59+7.1%Added
Abel Hall, LLC874$324.8K0.06%+874New
Glenmede Trust Co NA874$324.8K0.00%+874New
iA Global Asset Management Inc.870$323.0K0.00%+870New
Fiduciary Trust Co840$312.2K0.00%00.0%Unchanged
Archer Investment Corp830$308.5K0.06%+100+13.7%Added
Diametric Capital, LP830$308.5K0.03%+830New
Pinnacle Wealth Planning Services, Inc.814$302.5K0.03%+20+2.5%Added
Camden Capital, LLC800$297.3K0.01%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.764$284.0K0.00%−383−33.4%Reduced
Mitsubishi UFJ Trust & Banking Corp757$281.4K0.00%+757New
Shelton Capital Management718$266.9K0.00%−122−14.5%Reduced
Exchange Traded Concepts, LLC714$265.4K0.00%+26+3.8%Added
Ritholtz Wealth Management701$260.5K0.00%+701New
Oppenheimer Asset Management Inc.696$258.7K0.00%−97−12.2%Reduced
PSP Research LLC692$257.2K0.14%+692New
KBC Group NV685$255.0K0.00%00.0%Unchanged