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Krystal Biotech, Inc.

KRYS
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001711279

In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Krystal Biotech, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
422
+57 vs. Q1 2026
Shares held
30.3M
+2.19M (+7.8%) vs. Q1 2026
Total value
$11.1B
+$3.82B (+52.7%) vs. Q1 2026
New holders
93
178 more added
Sold out
36
109 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 422 institutions
Q1 2021: 113 institutionsQ2 2021: 113 institutionsQ3 2021: 113 institutionsQ4 2021: 140 institutionsQ1 2022: 135 institutionsQ2 2022: 137 institutionsQ3 2022: 148 institutionsQ4 2022: 154 institutionsQ1 2023: 160 institutionsQ2 2023: 183 institutionsQ3 2023: 188 institutionsQ4 2023: 194 institutionsQ1 2024: 234 institutionsQ2 2024: 245 institutionsQ3 2024: 283 institutionsQ4 2024: 264 institutionsQ1 2025: 299 institutionsQ2 2025: 275 institutionsQ3 2025: 284 institutionsQ4 2025: 334 institutionsQ1 2026: 368 institutionsQ2 2026: 422 institutions
Value heldQ2 2026: $11.1B
Q1 2021: $1.27BQ2 2021: $1.12BQ3 2021: $850.7MQ4 2021: $1.35BQ1 2022: $1.37BQ2 2022: $1.36BQ3 2022: $1.45BQ4 2022: $1.66BQ1 2023: $1.68BQ2 2023: $2.71BQ3 2023: $2.76BQ4 2023: $3.03BQ1 2024: $4.49BQ2 2024: $5.24BQ3 2024: $5.15BQ4 2024: $4.35BQ1 2025: $4.98BQ2 2025: $3.80BQ3 2025: $4.94BQ4 2025: $7.01BQ1 2026: $7.32BQ2 2026: $11.1B
Institutions holding KRYS and their total value by quarter
QuarterHoldersValue
Q2 2026422$11.1B
Q1 2026368$7.32B
Q4 2025334$7.01B
Q3 2025284$4.94B
Q2 2025275$3.80B
Q1 2025299$4.98B
Q4 2024264$4.35B
Q3 2024283$5.15B
Q2 2024245$5.24B
Q1 2024234$4.49B
Q4 2023194$3.03B
Q3 2023188$2.76B
Q2 2023183$2.71B
Q1 2023160$1.68B
Q4 2022154$1.66B
Q3 2022148$1.45B
Q2 2022137$1.36B
Q1 2022135$1.37B
Q4 2021140$1.35B
Q3 2021113$850.7M
Q2 2021113$1.12B
Q1 2021113$1.27B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q1 2026.

Institutions holding KRYS in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Mediolanum International Funds Ltd15,940$6.03M0.05%+15,940New
Castleark Management LLC16,150$6.00M0.16%−15,480−48.9%Reduced
SG Americas Securities, LLC16,147$6.00M0.00%+10,248+173.7%Added
WCM Investment Management, LLC15,753$5.96M0.01%+15,753New
Cim, LLC15,703$5.84M0.75%+713+4.8%Added
Mirae Asset Global ETFs Holdings Ltd.15,297$5.69M0.01%+176+1.2%Added
EFG International AG15,304$5.69M0.10%−4,745−23.7%Reduced
MetLife Investment Management15,196$5.65M0.03%+1,654+12.2%Added
State Board of Administration of Florida Retirement System14,483$5.38M0.01%−1,273−8.1%Reduced
Fiera Capital Corp14,251$5.30M0.02%−9,895−41.0%Reduced
AQR Capital Management LLC14,002$5.20M0.00%−112−0.8%Reduced
Natixis Advisors, L.P.13,649$5.07M0.01%+1,524+12.6%Added
Illinois Municipal Retirement Fund13,455$5.00M0.06%−696−4.9%Reduced
State of Alaska, Department of Revenue13,385$4.97M0.05%−4,099−23.4%Reduced
Envestnet Asset Management Inc13,212$4.91M0.00%+1,229+10.3%Added
Kornitzer Capital Management Inc13,126$4.88M0.10%+13,126New
State of Wisconsin Investment Board12,998$4.83M0.01%−7,693−37.2%Reduced
Credit Agricole S A12,976$4.82M0.01%00.0%Unchanged
Allianz Asset Management GmbH12,731$4.73M0.00%+10,831+570.1%Added
Nomura Asset Management International Inc.12,642$4.70M0.01%+2,424+23.7%Added
Torray LLC12,156$4.52M0.61%+124+1.0%Added
Commonwealth Equity Services, LLC12,116$4.50M0.01%+525+4.5%Added
Bridge City Capital, LLC11,816$4.39M1.00%−229−1.9%Reduced
Vanguard Global Advisers, LLC11,759$4.37M0.00%+483+4.3%Added
Louisiana State Employees Retirement System11,500$4.27M0.06%+100+0.9%Added
Privium Fund Management B.V.11,170$4.15M0.76%00.0%Unchanged
Brown Capital Management LLC10,968$4.08M0.81%+1,721+18.6%Added
Intech Investment Management LLC10,525$3.91M0.04%−2,995−22.2%Reduced
Advisor Group Holdings, Inc.10,498$3.90M0.00%+10,075+2,381.8%Added
Virginia Retirement Systems Et Al10,400$3.87M0.02%+900+9.5%Added
Palisade Capital Management LLC10,065$3.74M0.16%+10,065New
State of Tennessee, Treasury Department9,845$3.66M0.01%−409−4.0%Reduced
HSBC Holdings PLC9,598$3.65M0.00%+9,598New
Odyssean, LLC9,349$3.47M0.57%+4,530+94.0%Added
Clough Capital Partners L P9,257$3.44M0.28%+755+8.9%Added
Kennedy Capital Management, Inc.9,034$3.36M0.06%+4,130+84.2%Added
Erste Asset Management GmbH8,700$3.29M0.03%00.0%Unchanged
Rafferty Asset Management, LLC8,836$3.28M0.01%−8,851−50.0%Reduced
Legato Capital Management LLC8,713$3.24M0.27%+1,740+25.0%Added
Cetera Investment Advisers8,361$3.11M0.00%+2,155+34.7%Added
Evolutionary Tree Capital Management, LLC8,301$3.09M5.82%−4,013−32.6%Reduced
Police & Firemen's Retirement System of New Jersey7,709$2.87M0.02%+962+14.3%Added
Tealwood Asset Management Inc7,561$2.81M1.08%−103−1.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)7,452$2.77M0.01%+2,313+45.0%Added
Barclays PLC7,436$2.76M0.00%+2,467+49.6%Added
Martingale Asset Management L P7,311$2.72M0.06%+103+1.4%Added
Yousif Capital Management, LLC7,192$2.67M0.03%+61+0.9%Added
Amalgamated Bank7,045$2.62M0.02%−334−4.5%Reduced
STRS Ohio6,800$2.53M0.01%+400+6.3%Added
Guggenheim Capital LLC6,720$2.50M0.02%+3,202+91.0%Added
State of New Jersey Common Pension Fund D6,662$2.48M0.01%−771−10.4%Reduced
Transcend Wealth Collective, LLC6,522$2.42M0.16%+4,011+159.7%Added
Fifth Third Bancorp6,521$2.42M0.00%+596+10.1%Added
Teachers Retirement System of the State of Kentucky6,458$2.40M0.02%00.0%Unchanged
Commonwealth of Pennsylvania Public School Empls Retrmt Sys6,222$2.31M0.01%−160−2.5%Reduced
American Century Companies Inc6,204$2.31M0.00%+3,487+128.3%Added
Quantum Private Wealth, LLC6,119$2.27M0.58%−1,062−14.8%Reduced
Two Sigma Investments, LP6,084$2.26M0.00%+6,084New
Atika Capital Management LLC6,000$2.23M0.22%−4,625−43.5%Reduced
Oregon Public Employees Retirement Fund5,998$2.23M0.02%+49+0.8%Added
Profund Advisors LLC5,770$2.14M0.06%−3,020−34.4%Reduced
Arizona State Retirement System5,686$2.11M0.01%−287−4.8%Reduced
Vanguard Investments Australia, Ltd.5,615$2.09M0.01%+285+5.3%Added
RE Advisers Corp5,500$2.04M0.05%+5,500New
Fred Alger Management, LLC5,418$2.01M0.01%+5,418New
Penserra Capital Management LLC5,142$1.91M0.01%+5,142New
USS Investment Management Ltd4,900$1.82M0.01%+4,900New
Cookson Peirce & Co Inc4,898$1.82M0.06%+204+4.3%Added
Cambridge Investment Research Advisors, Inc.4,805$1.79M0.00%+4,805New
KLP Kapitalforvaltning AS4,800$1.78M0.01%00.0%Unchanged
State of Wyoming4,767$1.77M0.18%+4,767New
ProShare Advisors LLC4,760$1.77M0.00%−417−8.1%Reduced
China Universal Asset Management Co., Ltd.4,692$1.74M0.10%−495−9.5%Reduced
Toth Financial Advisory Corp4,511$1.68M0.16%+4,505+75,083.3%Added
Amundi4,368$1.62M0.00%−1,338−23.4%Reduced
LPL Financial LLC4,317$1.60M0.00%+2,552+144.6%Added
Knights of Columbus Asset Advisors LLC4,175$1.55M0.08%+4,175New
Quantinno Capital Management LP4,018$1.49M0.00%+847+26.7%Added
Regal Investment Advisors LLC3,913$1.45M0.08%−137−3.4%Reduced
Omers Administration Corp3,880$1.44M0.01%−220−5.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH3,822$1.42M0.00%−2,407−38.6%Reduced
Maryland State Retirement & Pension System3,816$1.42M0.02%+52+1.4%Added
Confluence Wealth Services, Inc.3,792$1.41M0.04%+870+29.8%Added
Assetmark, Inc3,739$1.39M0.00%+582+18.4%Added
Virtus Investment Advisers, Inc.3,657$1.36M0.32%+208+6.0%Added
Resona Asset Management Co.,Ltd.3,387$1.26M0.01%+193+6.0%Added
JustInvest LLC3,309$1.23M0.01%+282+9.3%Added
Bank of Montreal3,291$1.22M0.00%+129+4.1%Added
HighVista Strategies LLC3,260$1.21M0.28%+1,436+78.7%Added
New York Life Investment Management LLC3,167$1.18M0.01%+3,167New
Hanseatic Management Services Inc3,120$1.16M0.85%+123+4.1%Added
Ellsworth Advisors, LLC3,268$1.14M0.19%+23+0.7%Added
Stifel Financial Corp2,800$1.04M0.00%+2,800New
Citadel Advisors LLC2,725$1.01M0.00%−10.0%Reduced
Sanctuary Advisors, LLC2,692$1.00M0.00%−3,338−55.4%Reduced
Pathstone Holdings, LLC2,672$993.1K0.00%+431+19.2%Added
The PNC Financial Services Group, Inc.2,631$977.9K0.00%+646+32.5%Added
Xponance, Inc.2,522$937.4K0.01%+183+7.8%Added
Cornell Pochily Investment Advisors, Inc.2,515$934.8K0.25%+2,515New
Susquehanna Portfolio Strategies, LLC2,495$927.3K0.01%−1,609−39.2%Reduced