Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Krystal Biotech, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 284
- +15 vs. Q2 2025
- Shares held
- 28.0M
- +649.0K (+2.4%) vs. Q2 2025
- Total value
- $4.94B
- +$1.18B (+31.5%) vs. Q2 2025
- New holders
- 46
- 106 more added
- Sold out
- 31
- 86 more reduced
6 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avanza Fonder AB | 1,418 | $250.3K | 0.01% | +477+50.7% | Added |
| Bellevue Group AG | 1,312 | $231.6K | 0.00% | +62+5.0% | Added |
| Gotham Asset Management, LLC | 1,307 | $230.7K | 0.00% | +1,307 | New |
| Argent Trust Co | 1,307 | $230.7K | 0.01% | +1,307 | New |
| Oppenheimer Asset Management Inc. | 1,263 | $223.0K | 0.00% | +1,263 | New |
| Hohimer Wealth Management, LLC | 1,215 | $214.5K | 0.03% | +1,215 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,119 | $197.5K | 0.00% | +3+0.3% | Added |
| Tower Research Capital LLC (TRC) | 993 | $175.3K | 0.00% | −2,005−66.9% | Reduced |
| Nisa Investment Advisors, LLC | 926 | $163.5K | 0.00% | +40+4.5% | Added |
| Advisory Services Network, LLC | 854 | $150.8K | 0.00% | +854 | New |
| KBC Group NV | 685 | $121.0K | 0.00% | 00.0% | Unchanged |
| Quest Partners LLC | 664 | $117.2K | 0.01% | +85+14.7% | Added |
| GF Fund Management Co. Ltd. | 623 | $110.0K | 0.00% | −113−15.4% | Reduced |
| Pacer Advisors, Inc. | 607 | $107.2K | 0.00% | +152+33.4% | Added |
| Canada Pension Plan Investment Board | 600 | $105.9K | 0.00% | −400−40.0% | Reduced |
| GAMMA Investing LLC | 497 | $87.7K | 0.00% | +212+74.4% | Added |
| Exchange Traded Concepts, LLC | 496 | $87.6K | 0.00% | +496 | New |
| Smartleaf Asset Management LLC | 422 | $74.6K | 0.00% | +212+101.0% | Added |
| Royal Bank of Canada | 398 | $70.0K | 0.00% | −1,413−78.0% | Reduced |
| Abich Financial Wealth Management LLC | 395 | $69.7K | 0.02% | +395 | New |
| Bryn Mawr Trust Co | 393 | $69.4K | 0.00% | +173+78.6% | Added |
| Advisor Group Holdings, Inc. | 388 | $61.9K | 0.00% | −5−1.3% | Reduced |
| Pilgrim Partners Asia Pte Ltd | 330 | $58.3K | 0.03% | +330 | New |
| US Bancorp | 310 | $54.7K | 0.00% | −194−38.5% | Reduced |
| Hantz Financial Services, Inc. | 292 | $52.0K | 0.00% | +111+61.3% | Added |
| MAI Capital Management | 284 | $50.1K | 0.00% | +126+79.7% | Added |
| SRS Capital Advisors, Inc. | 256 | $45.2K | 0.00% | +250+4,166.7% | Added |
| Caldwell Trust Co | 250 | $44.1K | 0.00% | 00.0% | Unchanged |
| Danske Bank A/S | 200 | $35.3K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 190 | $33.5K | 0.00% | −66−25.8% | Reduced |
| Salomon & Ludwin, LLC | 182 | $33.4K | 0.00% | +182 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 174 | $31.0K | 0.00% | 00.0% | Unchanged |
| AdvisorNet Financial, Inc | 171 | $30.2K | 0.00% | +171 | New |
| Group One Trading, L.P. | 160 | $28.2K | 0.00% | +160 | New |
| Key Financial Inc | 151 | $27.1K | 0.01% | 00.0% | Unchanged |
| Bessemer Group Inc | 149 | $26.0K | 0.00% | +77+106.9% | Added |
| Quadrant Capital Group LLC | 136 | $24.0K | 0.00% | +136 | New |
| Fifth Third Bancorp | 131 | $23.1K | 0.00% | +41+45.6% | Added |
| Natixis | 122 | $21.5K | 0.00% | +122 | New |
| Umb Bank N A | 107 | $18.9K | 0.00% | +64+148.8% | Added |
| Rockefeller Capital Management L.P. | 105 | $18.5K | 0.00% | +105 | New |
| Reyes Financial Architecture, Inc. | 100 | $17.7K | 0.01% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 91 | $16.0K | 0.00% | −13−12.5% | Reduced |
| Signaturefd, LLC | 90 | $15.9K | 0.00% | +11+13.9% | Added |
| IFP Advisors, Inc | 76 | $13.4K | 0.00% | +66+660.0% | Added |
| Massmutual Trust Co FSB | 72 | $12.7K | 0.00% | +12+20.0% | Added |
| Versant Capital Management, Inc | 71 | $12.5K | 0.00% | +2+2.9% | Added |
| SBI Securities Co., Ltd. | 68 | $12.0K | 0.00% | −2−2.9% | Reduced |
| Rise Advisors, LLC | 66 | $11.7K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 63 | $11.1K | 0.00% | +32+103.2% | Added |
| Sterling Capital Management LLC | 60 | $10.6K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 55 | $9.71K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 50 | $8.83K | 0.00% | 00.0% | Unchanged |
| Bare Financial Services, Inc | 43 | $7.59K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 37 | $6.21K | 0.00% | +5+15.6% | Added |
| GWM Advisors LLC | 34 | $6.06K | 0.00% | 00.0% | Unchanged |
| Quent Capital, LLC | 34 | $6.00K | 0.00% | +34 | New |
| Clearstead Advisors, LLC | 33 | $5.83K | 0.00% | +9+37.5% | Added |
| Farther Finance Advisors, LLC | 33 | $5.83K | 0.00% | +9+37.5% | Added |
| Rothschild Investment LLC | 26 | $4.59K | 0.00% | −13−33.3% | Reduced |
| Parkside Financial Bank & Trust | 25 | $4.42K | 0.00% | +10+66.7% | Added |
| Allworth Financial LP | 20 | $3.53K | 0.00% | −24−54.5% | Reduced |
| Trust Co of Vermont | 20 | $3.53K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 18 | $3.18K | 0.00% | +7+63.6% | Added |
| Principal Securities, Inc. | 17 | $3.00K | 0.00% | +7+70.0% | Added |
| Larson Financial Group LLC | 17 | $3.00K | 0.00% | +15+750.0% | Added |
| Bell Investment Advisors, Inc | 16 | $2.83K | 0.00% | −3−15.8% | Reduced |
| Farmers & Merchants Investments Inc | 15 | $2.65K | 0.00% | 00.0% | Unchanged |
| Wealthspire Advisors, LLC | 15 | $2.65K | 0.00% | +15 | New |
| Sound Income Strategies, LLC | 10 | $1.89K | 0.00% | 00.0% | Unchanged |
| JPL Wealth Management, LLC | 10 | $1.77K | 0.00% | +10 | New |
| Salem Investment Counselors Inc | 8 | $1.41K | 0.00% | +8 | New |
| Ronald Blue Trust, Inc. | 6 | $1.06K | 0.00% | 00.0% | Unchanged |
| Atlantic Trust, LLC | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Rakuten Securities, Inc. | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Glen Eagle Advisors, LLC | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Hughes Financial Services, LLC | 4 | $798 | 0.00% | 00.0% | Unchanged |
| Fortitude Family Office, LLC | 4 | $706 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 4 | $706 | 0.00% | +3+300.0% | Added |
| JFS Wealth Advisors, LLC | 2 | $354 | 0.00% | 00.0% | Unchanged |
| Retirement Wealth Solutions LLC | 2 | $354 | 0.00% | +2 | New |
| Abound Wealth Management | 1 | $177 | 0.00% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 1 | $177 | 0.00% | +1 | New |
| Avion Wealth | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Logos Global Management LP | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −89,800−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −53,934−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −30,252−100.0% | Sold out |
| Edgestream Partners, L.P. | 0 | $0 | 0.00% | −19,678−100.0% | Sold out |
| Sphera Funds Management Ltd. | 0 | $0 | 0.00% | −7,335−100.0% | Sold out |
| M&G Plc | 0 | $0 | 0.00% | −6,748−100.0% | Sold out |
| Shay Capital LLC | 0 | $0 | 0.00% | −6,500−100.0% | Sold out |
| Summit Global Investments | 0 | $0 | 0.00% | −4,547−100.0% | Sold out |
| Bryce Point Capital, LLC | 0 | $0 | 0.00% | −4,323−100.0% | Sold out |
| M&T Bank Corp | 0 | $0 | 0.00% | −3,785−100.0% | Sold out |
| Hennion & Walsh Asset Management, Inc. | 0 | $0 | 0.00% | −3,253−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −2,435−100.0% | Sold out |
| Tempus Wealth Planning, LLC | 0 | $0 | 0.00% | −2,379−100.0% | Sold out |
| Nebula Research & Development LLC | 0 | $0 | 0.00% | −2,355−100.0% | Sold out |
| Capstone Investment Advisors, LLC | 0 | $0 | 0.00% | −2,196−100.0% | Sold out |