Krystal Biotech, Inc.
KRYS- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001711279
In the last 90 days, Krystal Biotech, Inc. insiders filed 0 open-market purchases and 3 sales; 422 institutions reported holding it in 13F filings for Q2 2026, worth $11.1B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Krystal Biotech, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 284
- +15 vs. Q2 2025
- Shares held
- 28.0M
- +649.0K (+2.4%) vs. Q2 2025
- Total value
- $4.94B
- +$1.18B (+31.5%) vs. Q2 2025
- New holders
- 46
- 106 more added
- Sold out
- 31
- 86 more reduced
6 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting KRYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 422 | $11.1B |
| Q1 2026 | 368 | $7.32B |
| Q4 2025 | 334 | $7.01B |
| Q3 2025 | 284 | $4.94B |
| Q2 2025 | 275 | $3.80B |
| Q1 2025 | 299 | $4.98B |
| Q4 2024 | 264 | $4.35B |
| Q3 2024 | 283 | $5.15B |
| Q2 2024 | 245 | $5.24B |
| Q1 2024 | 234 | $4.49B |
| Q4 2023 | 194 | $3.03B |
| Q3 2023 | 188 | $2.76B |
| Q2 2023 | 183 | $2.71B |
| Q1 2023 | 160 | $1.68B |
| Q4 2022 | 154 | $1.66B |
| Q3 2022 | 148 | $1.45B |
| Q2 2022 | 137 | $1.36B |
| Q1 2022 | 135 | $1.37B |
| Q4 2021 | 140 | $1.35B |
| Q3 2021 | 113 | $850.7M |
| Q2 2021 | 113 | $1.12B |
| Q1 2021 | 113 | $1.27B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Krystal Biotech, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Abound Wealth Management | 1 | $177 | 0.00% | 00.0% | Unchanged |
| Tortoise Investment Management, LLC | 1 | $177 | 0.00% | +1 | New |
| JFS Wealth Advisors, LLC | 2 | $354 | 0.00% | 00.0% | Unchanged |
| Retirement Wealth Solutions LLC | 2 | $354 | 0.00% | +2 | New |
| Fortitude Family Office, LLC | 4 | $706 | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 4 | $706 | 0.00% | +3+300.0% | Added |
| Hughes Financial Services, LLC | 4 | $798 | 0.00% | 00.0% | Unchanged |
| Atlantic Trust, LLC | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Rakuten Securities, Inc. | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Glen Eagle Advisors, LLC | 5 | $883 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 6 | $1.06K | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 8 | $1.41K | 0.00% | +8 | New |
| JPL Wealth Management, LLC | 10 | $1.77K | 0.00% | +10 | New |
| Sound Income Strategies, LLC | 10 | $1.89K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 15 | $2.65K | 0.00% | 00.0% | Unchanged |
| Wealthspire Advisors, LLC | 15 | $2.65K | 0.00% | +15 | New |
| Bell Investment Advisors, Inc | 16 | $2.83K | 0.00% | −3−15.8% | Reduced |
| Principal Securities, Inc. | 17 | $3.00K | 0.00% | +7+70.0% | Added |
| Larson Financial Group LLC | 17 | $3.00K | 0.00% | +15+750.0% | Added |
| Global Retirement Partners, LLC | 18 | $3.18K | 0.00% | +7+63.6% | Added |
| Allworth Financial LP | 20 | $3.53K | 0.00% | −24−54.5% | Reduced |
| Trust Co of Vermont | 20 | $3.53K | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 25 | $4.42K | 0.00% | +10+66.7% | Added |
| Rothschild Investment LLC | 26 | $4.59K | 0.00% | −13−33.3% | Reduced |
| Farther Finance Advisors, LLC | 33 | $5.83K | 0.00% | +9+37.5% | Added |
| Clearstead Advisors, LLC | 33 | $5.83K | 0.00% | +9+37.5% | Added |
| Quent Capital, LLC | 34 | $6.00K | 0.00% | +34 | New |
| GWM Advisors LLC | 34 | $6.06K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 37 | $6.21K | 0.00% | +5+15.6% | Added |
| Bare Financial Services, Inc | 43 | $7.59K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 50 | $8.83K | 0.00% | 00.0% | Unchanged |
| Private Wealth Management Group, LLC | 55 | $9.71K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 60 | $10.6K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 63 | $11.1K | 0.00% | +32+103.2% | Added |
| Rise Advisors, LLC | 66 | $11.7K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 68 | $12.0K | 0.00% | −2−2.9% | Reduced |
| Versant Capital Management, Inc | 71 | $12.5K | 0.00% | +2+2.9% | Added |
| Massmutual Trust Co FSB | 72 | $12.7K | 0.00% | +12+20.0% | Added |
| IFP Advisors, Inc | 76 | $13.4K | 0.00% | +66+660.0% | Added |
| Signaturefd, LLC | 90 | $15.9K | 0.00% | +11+13.9% | Added |
| Daiwa Securities Group Inc. | 91 | $16.0K | 0.00% | −13−12.5% | Reduced |
| Reyes Financial Architecture, Inc. | 100 | $17.7K | 0.01% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 105 | $18.5K | 0.00% | +105 | New |
| Umb Bank N A | 107 | $18.9K | 0.00% | +64+148.8% | Added |
| Natixis | 122 | $21.5K | 0.00% | +122 | New |
| Fifth Third Bancorp | 131 | $23.1K | 0.00% | +41+45.6% | Added |
| Quadrant Capital Group LLC | 136 | $24.0K | 0.00% | +136 | New |
| Bessemer Group Inc | 149 | $26.0K | 0.00% | +77+106.9% | Added |
| Key Financial Inc | 151 | $27.1K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 160 | $28.2K | 0.00% | +160 | New |
| AdvisorNet Financial, Inc | 171 | $30.2K | 0.00% | +171 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 174 | $31.0K | 0.00% | 00.0% | Unchanged |
| Salomon & Ludwin, LLC | 182 | $33.4K | 0.00% | +182 | New |
| Huntington National Bank | 190 | $33.5K | 0.00% | −66−25.8% | Reduced |
| Danske Bank A/S | 200 | $35.3K | 0.00% | 00.0% | Unchanged |
| Caldwell Trust Co | 250 | $44.1K | 0.00% | 00.0% | Unchanged |
| SRS Capital Advisors, Inc. | 256 | $45.2K | 0.00% | +250+4,166.7% | Added |
| MAI Capital Management | 284 | $50.1K | 0.00% | +126+79.7% | Added |
| Hantz Financial Services, Inc. | 292 | $52.0K | 0.00% | +111+61.3% | Added |
| US Bancorp | 310 | $54.7K | 0.00% | −194−38.5% | Reduced |
| Pilgrim Partners Asia Pte Ltd | 330 | $58.3K | 0.03% | +330 | New |
| Advisor Group Holdings, Inc. | 388 | $61.9K | 0.00% | −5−1.3% | Reduced |
| Bryn Mawr Trust Co | 393 | $69.4K | 0.00% | +173+78.6% | Added |
| Abich Financial Wealth Management LLC | 395 | $69.7K | 0.02% | +395 | New |
| Royal Bank of Canada | 398 | $70.0K | 0.00% | −1,413−78.0% | Reduced |
| Smartleaf Asset Management LLC | 422 | $74.6K | 0.00% | +212+101.0% | Added |
| Exchange Traded Concepts, LLC | 496 | $87.6K | 0.00% | +496 | New |
| GAMMA Investing LLC | 497 | $87.7K | 0.00% | +212+74.4% | Added |
| Canada Pension Plan Investment Board | 600 | $105.9K | 0.00% | −400−40.0% | Reduced |
| Pacer Advisors, Inc. | 607 | $107.2K | 0.00% | +152+33.4% | Added |
| GF Fund Management Co. Ltd. | 623 | $110.0K | 0.00% | −113−15.4% | Reduced |
| Quest Partners LLC | 664 | $117.2K | 0.01% | +85+14.7% | Added |
| KBC Group NV | 685 | $121.0K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 854 | $150.8K | 0.00% | +854 | New |
| Nisa Investment Advisors, LLC | 926 | $163.5K | 0.00% | +40+4.5% | Added |
| Tower Research Capital LLC (TRC) | 993 | $175.3K | 0.00% | −2,005−66.9% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,119 | $197.5K | 0.00% | +3+0.3% | Added |
| Hohimer Wealth Management, LLC | 1,215 | $214.5K | 0.03% | +1,215 | New |
| Oppenheimer Asset Management Inc. | 1,263 | $223.0K | 0.00% | +1,263 | New |
| Argent Trust Co | 1,307 | $230.7K | 0.01% | +1,307 | New |
| Gotham Asset Management, LLC | 1,307 | $230.7K | 0.00% | +1,307 | New |
| Bellevue Group AG | 1,312 | $231.6K | 0.00% | +62+5.0% | Added |
| Vident Advisory, LLC | 1,418 | $250.3K | 0.00% | −564−28.5% | Reduced |
| Avanza Fonder AB | 1,418 | $250.3K | 0.01% | +477+50.7% | Added |
| Mindset Wealth Management, LLC | 1,470 | $259.5K | 0.07% | +1,470 | New |
| O'Shaughnessy Asset Management, LLC | 1,485 | $262.1K | 0.00% | +1,485 | New |
| CWM, LLC | 1,536 | $271.0K | 0.00% | −47−3.0% | Reduced |
| Mackenzie Financial Corp | 1,597 | $281.9K | 0.00% | 00.0% | Unchanged |
| Transcend Wealth Collective, LLC | 1,680 | $296.6K | 0.02% | +1,680 | New |
| The PNC Financial Services Group, Inc. | 1,694 | $299.0K | 0.00% | +272+19.1% | Added |
| City Center Advisors, LLC | 1,702 | $300.5K | 0.29% | +1,702 | New |
| Campbell & CO Investment Adviser LLC | 1,721 | $303.8K | 0.02% | −270−13.6% | Reduced |
| Covestor Ltd | 1,778 | $314.0K | 0.17% | +405+29.5% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,798 | $317.4K | 0.00% | +3+0.2% | Added |
| Parallel Advisors, LLC | 1,863 | $328.9K | 0.01% | 00.0% | Unchanged |
| Altfest L J & Co Inc | 1,870 | $330.1K | 0.04% | +1,870 | New |
| Xponance, Inc. | 1,951 | $344.4K | 0.00% | +22+1.1% | Added |
| Virginia Retirement Systems Et Al | 2,000 | $353.1K | 0.00% | −5,800−74.4% | Reduced |
| Farallon Capital Management, L.L.C. | 2,000 | $353.1K | 0.00% | 00.0% | Unchanged |