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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q3 2026

Institutional positions in Design Therapeutics, Inc. as of Sep 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Q3 2026 data is still coming in (13F filing deadline: Nov 16, 2026), so these numbers are incomplete.

Institutional holders
1
−1 vs. Q2 2026
Shares held
86
−239 (−73.5%) vs. Q2 2026
Total value
$1.08K
−$3.62K (−77.0%) vs. Q2 2026
New holders
0
0 more added
Sold out
1
0 more reduced

134 institutions that held it in Q2 2026 haven't filed for Q3 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holders
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value held
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q3 2026

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q2 2026.

Institutions holding DSGN in Q3 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Versant Capital Management, Inc86$1.08K0.00%00.0%Unchanged
Massmutual Trust Co FSB0$00.00%−239−100.0%Sold out
Sr One Capital Management, LP––––Not filed
Logos Global Management LP––––Not filed
Baker Bros. Advisors LP––––Not filed
Driehaus Capital Management LLC––––Not filed
BlackRock, Inc.––––Not filed
Point72 Asset Management, L.P.––––Not filed
Trails Edge Capital Partners, LP––––Not filed
Frazier Life Sciences Management, L.P.––––Not filed
Vivo Capital, LLC––––Not filed
Vanguard Capital Management LLC––––Not filed
Caption Management, LLC––––Not filed
Almitas Capital LLC––––Not filed
Geode Capital Management, LLC––––Not filed
Sofinnova Investments, Inc.––––Not filed
FMR LLC––––Not filed
Morgan Stanley––––Not filed
State Street Corp––––Not filed
Woodline Partners LP––––Not filed
Dimensional Fund Advisors LP––––Not filed
Goldman Sachs Group Inc––––Not filed
Jacobs Levy Equity Management, Inc––––Not filed
Acadian Asset Management LLC––––Not filed
Siren, L.L.C.––––Not filed
Qube Research & Technologies Ltd––––Not filed
Renaissance Technologies LLC––––Not filed
Kennedy Capital Management, Inc.––––Not filed
Northern Trust Corp––––Not filed
Algert Global LLC––––Not filed
Acuta Capital Partners, LLC––––Not filed
Charles Schwab Investment Management Inc––––Not filed
Vanguard Portfolio Management LLC––––Not filed
Vanguard Fiduciary Trust Co––––Not filed
Prudential Financial Inc––––Not filed
D. E. Shaw & Co., Inc.––––Not filed
Eversept Partners, LP––––Not filed
KVP Capital Advisors, LP––––Not filed
J. Goldman & Co LP––––Not filed
Millennium Management LLC––––Not filed
Raymond James Financial Inc––––Not filed
Balyasny Asset Management LLC––––Not filed
Elmind Capital, LP––––Not filed
Nuveen, LLC––––Not filed
DAFNA Capital Management LLC––––Not filed
Bank of New York Mellon Corp––––Not filed
China Universal Asset Management Co., Ltd.––––Not filed
Citadel Advisors LLC––––Not filed
SummitTX Capital, L.P.––––Not filed
American Century Companies Inc––––Not filed
Palumbo Wealth Management LLC––––Not filed
AQR Capital Management LLC––––Not filed
Ameriprise Financial Inc––––Not filed
Russell Investments Group, Ltd.––––Not filed
Alps Advisors Inc––––Not filed
State of Wisconsin Investment Board––––Not filed
STRS Ohio––––Not filed
Verdad Advisers, LP––––Not filed
Bank of America Corp––––Not filed
ExodusPoint Capital Management, LP––––Not filed
Rhumbline Advisers––––Not filed
Vanguard Global Advisers, LLC––––Not filed
UBS Group AG––––Not filed
Susquehanna Portfolio Strategies, LLC––––Not filed
Two Sigma Investments, LP––––Not filed
Canada Pension Plan Investment Board––––Not filed
Oppenheimer & Co Inc––––Not filed
Alliancebernstein L.P.––––Not filed
Deutsche Bank AG––––Not filed
Virtus Investment Advisers, Inc.––––Not filed
Squarepoint Ops LLC––––Not filed
Trexquant Investment LP––––Not filed
Wells Fargo & Company––––Not filed
CI Private Wealth, LLC––––Not filed
Bridgeway Capital Management, LLC––––Not filed
Quantinno Capital Management LP––––Not filed
Price T Rowe Associates Inc––––Not filed
SEI Investments Co––––Not filed
XTX Topco Ltd––––Not filed
AlphaCentric Advisors LLC––––Not filed
Invesco Ltd.––––Not filed
Public Employees Retirement System of Ohio––––Not filed
MetLife Investment Management––––Not filed
Wellington Management Group LLP––––Not filed
JPMorgan Chase & Co––––Not filed
Citigroup Inc––––Not filed
Creative Planning––––Not filed
Susquehanna International Group, LLP––––Not filed
Nisa Investment Advisors, LLC––––Not filed
Mirae Asset Global ETFs Holdings Ltd.––––Not filed
Y-Intercept (Hong Kong) Ltd––––Not filed
Susquehanna Fundamental Investments, LLC––––Not filed
Royal Bank of Canada––––Not filed
Barclays PLC––––Not filed
New York State Common Retirement Fund––––Not filed
Gsa Capital Partners LLP––––Not filed
Police & Firemen's Retirement System of New Jersey––––Not filed
BNP Paribas Arbitrage, SA––––Not filed
Clearstead Advisors, LLC––––Not filed
Tower Research Capital LLC (TRC)––––Not filed