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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
125
+9 vs. Q4 2025
Shares held
38.0M
+1.50M (+4.1%) vs. Q4 2025
Total value
$404.1M
+$61.9M (+18.1%) vs. Q4 2025
New holders
22
56 more added
Sold out
13
28 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 125 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ1 2026: $404.1M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding DSGN in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
California State Teachers Retirement System1,292$13.7K0.00%−179−12.2%Reduced
GF Fund Management Co. Ltd.1,271$13.5K0.00%+153+13.7%Added
UBS Asset Management Americas Inc1,143$12.2K0.00%+763+200.8%Added
Sterling Capital Management LLC791$8.42K0.00%−586−42.6%Reduced
Clearstead Advisors, LLC610$6.49K0.00%00.0%Unchanged
Private Wealth Management Group, LLC533$5.67K0.00%−25−4.5%Reduced
CWM, LLC423$4.50K0.00%+184+77.0%Added
Farther Finance Advisors, LLC386$4.25K0.00%+1+0.3%Added
Advisor Group Holdings, Inc.306$3.26K0.00%+296+2,960.0%Added
UMA Financial Services, Inc.268$2.85K0.00%00.0%Unchanged
Massmutual Trust Co FSB239$2.54K0.00%00.0%Unchanged
Stone House Investment Management, LLC239$2.54K0.00%+239New
Optiver Holding B.V.224$2.38K0.00%−104−31.7%Reduced
Larson Financial Group LLC181$1.93K0.00%+178+5,933.3%Added
Allworth Financial LP130$1.38K0.00%+130New
US Bancorp61$6490.00%+61New
Root Financial Partners, LLC38$4040.00%+38New
Rothschild Investment LLC23$2450.00%+23New
EverSource Wealth Advisors, LLC10$1070.00%+7+233.3%Added
National Bank of Canada9$960.00%+9New
MAI Capital Management8$860.00%+8New
True Wealth Design, LLC1$110.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd1$110.00%+1New
Essential Partners LLC1$110.00%+1New
Capital Advisors, Ltd. LLC12$00.00%00.0%Unchanged
Frazier Life Sciences Management, L.P.0$00.00%−521,000−100.0%Sold out
Diadema Partners LP0$00.00%−100,320−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−61,852−100.0%Sold out
Persistent Asset Partners Ltd0$00.00%−34,989−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−25,300−100.0%Sold out
Virtu Financial LLC0$00.00%−22,651−100.0%Sold out
9823 Capital, L.P.0$00.00%−19,197−100.0%Sold out
Axq Capital, LP0$00.00%−11,728−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−11,396−100.0%Sold out
Torren Management, LLC0$00.00%−2,820−100.0%Sold out
Amalgamated Bank0$00.00%−751−100.0%Sold out
Daiwa Securities Group Inc.0$00.00%−100−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−47−100.0%Sold out
Vanguard Group Inc––––Not filed