Design Therapeutics, Inc.
DSGN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001807120
No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 125
- +9 vs. Q4 2025
- Shares held
- 38.0M
- +1.50M (+4.1%) vs. Q4 2025
- Total value
- $404.1M
- +$61.9M (+18.1%) vs. Q4 2025
- New holders
- 22
- 56 more added
- Sold out
- 13
- 28 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 136 | $626.4M |
| Q1 2026 | 125 | $404.1M |
| Q4 2025 | 117 | $357.6M |
| Q3 2025 | 95 | $259.7M |
| Q2 2025 | 93 | $116.4M |
| Q1 2025 | 98 | $133.0M |
| Q4 2024 | 95 | $206.5M |
| Q3 2024 | 100 | $172.3M |
| Q2 2024 | 95 | $107.5M |
| Q1 2024 | 93 | $123.9M |
| Q4 2023 | 88 | $84.0M |
| Q3 2023 | 87 | $77.6M |
| Q2 2023 | 97 | $244.4M |
| Q1 2023 | 96 | $223.3M |
| Q4 2022 | 83 | $414.2M |
| Q3 2022 | 79 | $667.2M |
| Q2 2022 | 74 | $541.7M |
| Q1 2022 | 63 | $613.7M |
| Q4 2021 | 60 | $773.1M |
| Q3 2021 | 52 | $414.8M |
| Q2 2021 | 50 | $546.2M |
| Q1 2021 | 43 | $755.2M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Capital Advisors, Ltd. LLC | 12 | $0 | 0.00% | 00.0% | Unchanged |
| True Wealth Design, LLC | 1 | $11 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 1 | $11 | 0.00% | +1 | New |
| Essential Partners LLC | 1 | $11 | 0.00% | +1 | New |
| MAI Capital Management | 8 | $86 | 0.00% | +8 | New |
| National Bank of Canada | 9 | $96 | 0.00% | +9 | New |
| EverSource Wealth Advisors, LLC | 10 | $107 | 0.00% | +7+233.3% | Added |
| Rothschild Investment LLC | 23 | $245 | 0.00% | +23 | New |
| Root Financial Partners, LLC | 38 | $404 | 0.00% | +38 | New |
| US Bancorp | 61 | $649 | 0.00% | +61 | New |
| Allworth Financial LP | 130 | $1.38K | 0.00% | +130 | New |
| Larson Financial Group LLC | 181 | $1.93K | 0.00% | +178+5,933.3% | Added |
| Optiver Holding B.V. | 224 | $2.38K | 0.00% | −104−31.7% | Reduced |
| Massmutual Trust Co FSB | 239 | $2.54K | 0.00% | 00.0% | Unchanged |
| Stone House Investment Management, LLC | 239 | $2.54K | 0.00% | +239 | New |
| UMA Financial Services, Inc. | 268 | $2.85K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 306 | $3.26K | 0.00% | +296+2,960.0% | Added |
| Farther Finance Advisors, LLC | 386 | $4.25K | 0.00% | +1+0.3% | Added |
| CWM, LLC | 423 | $4.50K | 0.00% | +184+77.0% | Added |
| Private Wealth Management Group, LLC | 533 | $5.67K | 0.00% | −25−4.5% | Reduced |
| Clearstead Advisors, LLC | 610 | $6.49K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 791 | $8.42K | 0.00% | −586−42.6% | Reduced |
| UBS Asset Management Americas Inc | 1,143 | $12.2K | 0.00% | +763+200.8% | Added |
| GF Fund Management Co. Ltd. | 1,271 | $13.5K | 0.00% | +153+13.7% | Added |
| California State Teachers Retirement System | 1,292 | $13.7K | 0.00% | −179−12.2% | Reduced |
| GAMMA Investing LLC | 1,472 | $15.7K | 0.00% | +722+96.3% | Added |
| Tower Research Capital LLC (TRC) | 1,545 | $16.4K | 0.00% | −2,728−63.8% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,594 | $17.0K | 0.00% | +367+29.9% | Added |
| The PNC Financial Services Group, Inc. | 1,816 | $19.3K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 2,026 | $21.6K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 2,077 | $22.1K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 2,570 | $27.3K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,971 | $31.6K | 0.00% | +203+7.3% | Added |
| Caz Investments LP | 3,500 | $37.2K | 0.04% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 3,684 | $39.2K | 0.00% | +2,946+399.2% | Added |
| Citigroup Inc | 4,263 | $45.4K | 0.00% | +1,150+36.9% | Added |
| Police & Firemen's Retirement System of New Jersey | 6,598 | $70.2K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 9,027 | $96.0K | 0.00% | −17,759−66.3% | Reduced |
| ADAR1 Capital Management, LLC | 10,000 | $106.4K | 0.01% | +10,000 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 11,363 | $120.9K | 0.00% | +272+2.5% | Added |
| Royal Bank of Canada | 11,366 | $121.0K | 0.00% | +10,728+1,681.5% | Added |
| Mirabella Financial Services LLP | 11,814 | $125.7K | 0.01% | +11,814 | New |
| Vanguard Global Advisers, LLC | 11,839 | $126.0K | 0.00% | +11,839 | New |
| Baader Bank INC | 12,792 | $136.1K | 0.01% | −7,208−36.0% | Reduced |
| Mariner, LLC | 13,066 | $138.9K | 0.00% | +244+1.9% | Added |
| JPMorgan Chase & Co | 14,134 | $146.6K | 0.00% | −317−2.2% | Reduced |
| Quantinno Capital Management LP | 14,128 | $150.3K | 0.00% | +14,128 | New |
| Dynamic Technology Lab Private Ltd | 14,749 | $156.9K | 0.03% | +14,749 | New |
| Nisa Investment Advisors, LLC | 14,824 | $157.7K | 0.00% | +3,000+25.4% | Added |
| Public Employees Retirement System of Ohio | 15,193 | $161.7K | 0.00% | +8,100+114.2% | Added |
| MetLife Investment Management | 15,249 | $162.2K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 15,294 | $162.7K | 0.00% | +15,294 | New |
| Engineers Gate Manager LP | 16,090 | $171.2K | 0.00% | +2,078+14.8% | Added |
| Two Sigma Investments, LP | 16,300 | $173.4K | 0.00% | −29,937−64.7% | Reduced |
| Price T Rowe Associates Inc | 16,370 | $175.0K | 0.00% | +659+4.2% | Added |
| UBS Group AG | 17,091 | $181.8K | 0.00% | −8,446−33.1% | Reduced |
| Velan Capital Investment Management LP | 20,000 | $212.8K | 0.13% | 00.0% | Unchanged |
| Deutsche Bank AG | 20,644 | $219.7K | 0.00% | +5,103+32.8% | Added |
| AlphaCentric Advisors LLC | 21,231 | $225.9K | 0.23% | +969+4.8% | Added |
| Bank of America Corp | 23,264 | $247.5K | 0.00% | −4,182−15.2% | Reduced |
| Russell Investments Group, Ltd. | 25,437 | $270.6K | 0.00% | +203+0.8% | Added |
| AQR Capital Management LLC | 25,957 | $276.2K | 0.00% | +12,227+89.1% | Added |
| CI Private Wealth, LLC | 27,169 | $289.1K | 0.00% | +204+0.8% | Added |
| Qube Research & Technologies Ltd | 34,183 | $363.7K | 0.00% | +34,183 | New |
| Rhumbline Advisers | 34,860 | $370.9K | 0.00% | +82+0.2% | Added |
| Ameriprise Financial Inc | 34,990 | $372.3K | 0.00% | −123,393−77.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 35,109 | $373.6K | 0.03% | +827+2.4% | Added |
| Alliancebernstein L.P. | 46,120 | $432.6K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 44,700 | $475.6K | 0.00% | +19,500+77.4% | Added |
| Prudential Financial Inc | 45,810 | $487.4K | 0.00% | +3,100+7.3% | Added |
| State of Wisconsin Investment Board | 49,214 | $523.6K | 0.00% | −1,443−2.8% | Reduced |
| Alps Advisors Inc | 50,209 | $534.2K | 0.00% | +3,438+7.4% | Added |
| BNP Paribas Arbitrage, SA | 50,272 | $534.9K | 0.00% | −44,556−47.0% | Reduced |
| Bridgeway Capital Management, LLC | 52,000 | $553.3K | 0.01% | −26,500−33.8% | Reduced |
| Barclays PLC | 55,790 | $593.6K | 0.00% | −31,270−35.9% | Reduced |
| Canada Pension Plan Investment Board | 60,400 | $642.7K | 0.00% | +5,800+10.6% | Added |
| XTX Topco Ltd | 60,939 | $648.4K | 0.01% | +25,655+72.7% | Added |
| American Century Companies Inc | 65,638 | $698.4K | 0.00% | +7,840+13.6% | Added |
| Palumbo Wealth Management LLC | 71,408 | $759.8K | 0.19% | +2,031+2.9% | Added |
| EAM Investors, LLC | 78,949 | $840.0K | 0.10% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 79,645 | $847.4K | 0.00% | −5,330−6.3% | Reduced |
| Squarepoint Ops LLC | 86,117 | $916.3K | 0.00% | +39,975+86.6% | Added |
| Caption Management, LLC | 86,708 | $922.6K | 0.04% | +86,708 | New |
| Verdad Advisers, LP | 92,310 | $982.2K | 1.11% | +92,310 | New |
| Jane Street Group, LLC | 103,902 | $1.11M | 0.00% | −122,610−54.1% | Reduced |
| Raymond James Financial Inc | 108,449 | $1.15M | 0.00% | −1,314−1.2% | Reduced |
| Millennium Management LLC | 108,928 | $1.16M | 0.00% | −71,938−39.8% | Reduced |
| Trexquant Investment LP | 117,111 | $1.25M | 0.01% | +17,144+17.1% | Added |
| Lynx1 Capital Management LP | 119,516 | $1.27M | 0.20% | +50,000+71.9% | Added |
| Nuveen, LLC | 126,815 | $1.35M | 0.00% | +1,555+1.2% | Added |
| SEI Investments Co | 133,203 | $1.42M | 0.00% | +80,473+152.6% | Added |
| Vanguard Portfolio Management LLC | 138,565 | $1.47M | 0.00% | +138,565 | New |
| Invesco Ltd. | 141,920 | $1.51M | 0.00% | −163,837−53.6% | Reduced |
| Acuta Capital Partners, LLC | 145,900 | $1.55M | 1.10% | −5,006−3.3% | Reduced |
| Marshall Wace, LLP | 151,008 | $1.61M | 0.00% | −74,520−33.0% | Reduced |
| Vanguard Fiduciary Trust Co | 195,658 | $2.08M | 0.00% | +195,658 | New |
| Algert Global LLC | 204,739 | $2.18M | 0.03% | +16,970+9.0% | Added |
| Elmind Capital, LP | 207,900 | $2.21M | 0.63% | 00.0% | Unchanged |
| Citadel Advisors LLC | 231,513 | $2.46M | 0.00% | −228,361−49.7% | Reduced |
| Charles Schwab Investment Management Inc | 241,485 | $2.57M | 0.00% | +4,622+2.0% | Added |