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Design Therapeutics, Inc.

DSGN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001807120

No open-market purchases or sales by Design Therapeutics, Inc. insiders were filed in the last 90 days; 136 institutions reported holding it in 13F filings for Q2 2026, worth $626.4M in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Design Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
63
+3 vs. Q4 2021
Shares held
38.0M
+1.82M (+5.0%) vs. Q4 2021
Total value
$613.7M
−$159.4M (−20.6%) vs. Q4 2021
New holders
6
30 more added
Sold out
3
16 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DSGN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 63 institutions
Q1 2021: 43 institutionsQ2 2021: 50 institutionsQ3 2021: 52 institutionsQ4 2021: 60 institutionsQ1 2022: 63 institutionsQ2 2022: 74 institutionsQ3 2022: 79 institutionsQ4 2022: 83 institutionsQ1 2023: 96 institutionsQ2 2023: 97 institutionsQ3 2023: 87 institutionsQ4 2023: 88 institutionsQ1 2024: 93 institutionsQ2 2024: 95 institutionsQ3 2024: 100 institutionsQ4 2024: 95 institutionsQ1 2025: 98 institutionsQ2 2025: 93 institutionsQ3 2025: 95 institutionsQ4 2025: 117 institutionsQ1 2026: 125 institutionsQ2 2026: 136 institutions
Value heldQ1 2022: $613.7M
Q1 2021: $755.2MQ2 2021: $546.2MQ3 2021: $414.8MQ4 2021: $773.1MQ1 2022: $613.7MQ2 2022: $541.7MQ3 2022: $667.2MQ4 2022: $414.2MQ1 2023: $223.3MQ2 2023: $244.4MQ3 2023: $77.6MQ4 2023: $84.0MQ1 2024: $123.9MQ2 2024: $107.5MQ3 2024: $172.3MQ4 2024: $206.5MQ1 2025: $133.0MQ2 2025: $116.4MQ3 2025: $259.7MQ4 2025: $357.6MQ1 2026: $404.1MQ2 2026: $626.4M
Institutions holding DSGN and their total value by quarter
QuarterHoldersValue
Q2 2026136$626.4M
Q1 2026125$404.1M
Q4 2025117$357.6M
Q3 202595$259.7M
Q2 202593$116.4M
Q1 202598$133.0M
Q4 202495$206.5M
Q3 2024100$172.3M
Q2 202495$107.5M
Q1 202493$123.9M
Q4 202388$84.0M
Q3 202387$77.6M
Q2 202397$244.4M
Q1 202396$223.3M
Q4 202283$414.2M
Q3 202279$667.2M
Q2 202274$541.7M
Q1 202263$613.7M
Q4 202160$773.1M
Q3 202152$414.8M
Q2 202150$546.2M
Q1 202143$755.2M

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Design Therapeutics, Inc.; share changes are against Q4 2021.

Institutions holding DSGN in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of Wyoming93$2.00K0.00%+16+20.8%Added
Daiwa Securities Group Inc.162$3.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.233$4.00K0.00%+28+13.7%Added
Assetmark, Inc263$4.00K0.00%+263New
Tower Research Capital LLC (TRC)390$6.00K0.00%−881−69.3%Reduced
Wells Fargo & Company653$10.0K0.00%−9,290−93.4%Reduced
UBS Group AG998$16.0K0.00%+963+2,751.4%Added
Zurcher Kantonalbank (Zurich Cantonalbank)1,448$23.0K0.00%+1,448New
Prospera Financial Services Inc1,404$23.0K0.00%+1,404New
Royal Bank of Canada1,634$26.0K0.00%−4,267−72.3%Reduced
Metropolitan Life Insurance Co2,027$32.7K0.00%−6,021−74.8%Reduced
Ameritas Investment Partners, Inc.2,055$33.0K0.00%00.0%Unchanged
Legal & General Group Plc2,536$41.0K0.00%+73+3.0%Added
Amalgamated Bank3,871$63.0K0.00%+3,871New
Amalgamated Financial Corp.3,871$63.0K0.00%+3,871New
ProShare Advisors LLC10,755$174.0K0.00%−2,841−20.9%Reduced
California State Teachers Retirement System11,428$185.0K0.00%−3,093−21.3%Reduced
Morgan Stanley12,816$207.0K0.00%−488−3.7%Reduced
American International Group, Inc.13,202$213.0K0.00%−930−6.6%Reduced
Deutsche Bank AG14,790$239.0K0.00%−2,228−13.1%Reduced
MetLife Investment Management16,885$272.7K0.00%+6,021+55.4%Added
DekaBank Deutsche Girozentrale18,700$299.0K0.00%+1,700+10.0%Added
Citigroup Inc18,722$302.0K0.00%−9,477−33.6%Reduced
JPMorgan Chase & Co20,239$327.0K0.00%+4,504+28.6%Added
Qube Research & Technologies Ltd20,396$329.0K0.00%−2,656−11.5%Reduced
New York State Common Retirement Fund21,876$353.0K0.00%+8,919+68.8%Added
Rhumbline Advisers28,284$457.0K0.00%+4,995+21.4%Added
State of Wisconsin Investment Board35,600$575.0K0.00%+18,200+104.6%Added
TD Asset Management Inc44,318$716.0K0.00%−21,400−32.6%Reduced
Manufacturers Life Insurance Company, The49,479$793.7K0.00%+36,353+277.0%Added
Ensign Peak Advisors, Inc50,000$808.0K0.00%00.0%Unchanged
Bank of America Corp57,199$924.0K0.00%+2,262+4.1%Added
Tekla Capital Management LLC65,351$1.05M0.04%00.0%Unchanged
Bank of New York Mellon Corp89,956$1.45M0.00%+22,848+34.0%Added
Nuveen Asset Management, LLC79,078$1.47M0.00%+5,965+8.2%Added
Goldman Sachs Group Inc117,132$1.89M0.00%+49,294+72.7%Added
Charles Schwab Investment Management Inc122,368$1.98M0.00%+3,812+3.2%Added
Norges Bank200,000$3.23M0.00%00.0%Unchanged
Adage Capital Partners GP, L.L.C.200,000$3.23M0.01%+35,000+21.2%Added
Ghost Tree Capital, LLC200,000$3.23M1.60%+65,000+48.1%Added
Northern Trust Corp211,034$3.41M0.00%−981−0.5%Reduced
Barclays PLC226,511$3.66M0.00%+226,511New
Rock Springs Capital Management LP345,597$5.58M0.14%+10,350+3.1%Added
Geode Capital Management, LLC366,745$5.92M0.00%+15,304+4.4%Added
Artal Group S.A.400,000$6.46M0.27%00.0%Unchanged
Eventide Asset Management, LLC400,000$6.46M0.10%00.0%Unchanged
State Street Corp403,541$6.52M0.00%+61,280+17.9%Added
Vivo Capital, LLC476,589$7.70M0.53%−54,402−10.2%Reduced
Principal Financial Group Inc543,912$8.78M0.01%+21,458+4.1%Added
Price T Rowe Associates Inc574,012$9.27M0.00%−213,653−27.1%Reduced
Wellington Management Group LLP999,173$16.1M0.00%+143,635+16.8%Added
FMR LLC1,027,366$16.6M0.00%+27,366+2.7%Added
Janus Henderson Group PLC1,118,551$18.1M0.01%+181,784+19.4%Added
Baker Bros. Advisors LP1,436,636$23.2M0.13%00.0%Unchanged
Vanguard Group Inc1,873,893$30.3M0.00%+3,391+0.2%Added
Ra Capital Management, L.P.2,186,636$35.3M0.77%00.0%Unchanged
Avoro Capital Advisors LLC2,222,222$35.9M0.66%+586,122+35.8%Added
EcoR1 Capital, LLC2,371,445$38.3M1.20%+218,448+10.1%Added
Citadel Advisors LLC2,534,702$40.9M0.05%00.0%Unchanged
Logos Global Management LP2,797,501$45.2M5.86%+25,000+0.9%Added
BlackRock Inc.3,150,820$50.9M0.00%+935,196+42.2%Added
Cormorant Asset Management, LP5,156,994$83.3M6.39%−283,459−5.2%Reduced
Sr One Capital Management, LP5,626,476$90.9M46.52%00.0%Unchanged
HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse)0$00.00%−280,991−100.0%Sold out
Invesco Ltd.0$00.00%−9,622−100.0%Sold out
SG Americas Securities, LLC0$00.00%−5,639−100.0%Sold out