Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 95
- −2 vs. Q4 2024
- Shares held
- 41.7M
- −155.0K (−0.4%) vs. Q4 2024
- Total value
- $354.4M
- −$232.1M (−39.6%) vs. Q4 2024
- New holders
- 15
- 28 more added
- Sold out
- 17
- 30 more reduced
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 10,885,357 | $92.4M | 1.02% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 3,692,069 | $31.3M | 0.09% | −862,831−18.9% | Reduced |
| FCPM III Services B.V. | 3,452,330 | $29.3M | 7.08% | 00.0% | Unchanged |
| Armistice Capital, LLC | 2,672,000 | $22.7M | 0.61% | +476,000+21.7% | Added |
| Westfield Capital Management Co LP | 2,657,305 | $22.6M | 0.11% | +46,968+1.8% | Added |
| Siren, L.L.C. | 1,812,752 | $15.4M | 0.87% | −26,646−1.4% | Reduced |
| Price T Rowe Associates Inc | 1,536,584 | $13.0M | 0.00% | −48,543−3.1% | Reduced |
| Long Focus Capital Management, LLC | 1,293,753 | $11.0M | 0.75% | +750,661+138.2% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,219,688 | $10.4M | 0.03% | +64,037+5.5% | Added |
| Candriam Luxembourg S.C.A. | 1,205,207 | $10.2M | 0.06% | +117,331+10.8% | Added |
| Ra Capital Management, L.P. | 1,093,477 | $9.28M | 0.16% | 00.0% | Unchanged |
| Morgan Stanley | 999,837 | $8.49M | 0.00% | +137,700+16.0% | Added |
| EcoR1 Capital, LLC | 910,000 | $7.73M | 0.46% | 00.0% | Unchanged |
| Deep Track Capital, LP | 767,016 | $6.51M | 0.21% | −509,065−39.9% | Reduced |
| Principal Financial Group Inc | 631,260 | $5.36M | 0.00% | +224,790+55.3% | Added |
| Tybourne Capital Management (HK) Ltd | 576,343 | $4.89M | 20.77% | −693,192−54.6% | Reduced |
| Bank of America Corp | 563,559 | $4.78M | 0.00% | +170,700+43.5% | Added |
| AXA S.A. | 553,682 | $4.70M | 0.02% | −277−0.1% | Reduced |
| Millennium Management LLC | 453,428 | $3.85M | 0.00% | +276,671+156.5% | Added |
| Jefferies Financial Group Inc. | 408,889 | $3.47M | 0.06% | +408,889 | New |
| Woodline Partners LP | 363,751 | $3.09M | 0.02% | +363,751 | New |
| BlackRock, Inc. | 322,876 | $2.74M | 0.00% | −42,532−11.6% | Reduced |
| Renaissance Technologies LLC | 301,500 | $2.56M | 0.00% | +32,000+11.9% | Added |
| Platinum Investment Management Ltd | 287,599 | $2.44M | 0.14% | −21,460−6.9% | Reduced |
| Silvercrest Asset Management Group LLC | 265,693 | $2.26M | 0.02% | +127,953+92.9% | Added |
| Palo Alto Investors LP | 248,934 | $2.11M | 0.40% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 215,900 | $1.83M | 0.01% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 214,278 | $1.82M | 0.03% | −12,464−5.5% | Reduced |
| TD Asset Management Inc | 193,092 | $1.64M | 0.00% | −22,924−10.6% | Reduced |
| Aquilo Capital Management, LLC | 171,695 | $1.46M | 3.93% | −50,216−22.6% | Reduced |
| UBS Oconnor LLC | 148,722 | $1.26M | 0.03% | +68,486+85.4% | Added |
| Harbor Capital Advisors, Inc. | 148,129 | $1.26M | 0.06% | +16,624+12.6% | Added |
| Manufacturers Life Insurance Company, The | 138,249 | $1.17M | 0.00% | +13,752+11.0% | Added |
| Legal & General Group Plc | 135,658 | $1.17M | 0.00% | −3,417−2.5% | Reduced |
| Citadel Advisors LLC | 130,070 | $1.10M | 0.00% | −14,160−9.8% | Reduced |
| Acadian Asset Management LLC | 126,062 | $1.06M | 0.00% | +126,062 | New |
| State Street Corp | 85,653 | $727.2K | 0.00% | −2,112−2.4% | Reduced |
| Caption Management, LLC | 81,559 | $692.4K | 0.03% | −81,517−50.0% | Reduced |
| DAFNA Capital Management LLC | 80,799 | $686.0K | 0.19% | −40,000−33.1% | Reduced |
| UBS Group AG | 72,702 | $617.2K | 0.00% | −59,659−45.1% | Reduced |
| Nan Fung Group Holdings Ltd | 68,943 | $585.3K | 0.48% | 00.0% | Unchanged |
| Shay Capital LLC | 60,000 | $509.4K | 0.15% | +60,000 | New |
| Moore Capital Management, LP | 50,000 | $424.5K | 0.01% | +50,000 | New |
| Cubist Systematic Strategies, LLC | 47,249 | $401.1K | 0.01% | −2,650−5.3% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 42,729 | $363.0K | 0.00% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 30,000 | $256.0K | 0.00% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 28,857 | $245.0K | 0.11% | −15,016−34.2% | Reduced |
| Goldman Sachs Group Inc | 25,192 | $213.9K | 0.00% | +25,192 | New |
| Woodstock Corp | 24,981 | $212.1K | 0.02% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 21,377 | $181.5K | 0.00% | −17,438−44.9% | Reduced |
| Tocqueville Asset Management L.P. | 18,300 | $155.4K | 0.00% | +3,600+24.5% | Added |
| Royal Bank of Canada | 17,940 | $152.0K | 0.00% | +8,167+83.6% | Added |
| Portland Investment Counsel Inc. | 15,000 | $127.3K | 0.04% | +15,000 | New |
| Erste Asset Management GmbH | 14,000 | $125.6K | 0.00% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 14,396 | $122.2K | 0.00% | 00.0% | Unchanged |
| Cerity Partners LLC | 13,350 | $113.3K | 0.00% | +13,350 | New |
| The PNC Financial Services Group, Inc. | 13,080 | $111.0K | 0.00% | +180+1.4% | Added |
| Exchange Traded Concepts, LLC | 12,764 | $108.4K | 0.00% | +6,057+90.3% | Added |
| Envestnet Asset Management Inc | 12,420 | $105.4K | 0.00% | +12,420 | New |
| Gsa Capital Partners LLP | 11,952 | $101.0K | 0.01% | +11,952 | New |
| Crossmark Global Holdings, Inc. | 11,400 | $96.8K | 0.00% | +22+0.2% | Added |
| SEI Investments Co | 10,637 | $90.3K | 0.00% | +10,637 | New |
| China Universal Asset Management Co., Ltd. | 8,833 | $75.0K | 0.01% | −496−5.3% | Reduced |
| Virtus Investment Advisers, Inc. | 8,162 | $69.3K | 0.02% | +8,162 | New |
| JPMorgan Chase & Co | 7,044 | $59.8K | 0.00% | −663−8.6% | Reduced |
| Deutsche Bank AG | 6,417 | $54.5K | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 5,100 | $43.3K | 0.00% | +5,100 | New |
| Barclays PLC | 3,308 | $28.1K | 0.00% | +696+26.6% | Added |
| Natixis | 2,126 | $17.9K | 0.00% | −172−7.5% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,464 | $13.1K | 0.00% | −2−0.1% | Reduced |
| Rhumbline Advisers | 1,304 | $11.1K | 0.00% | +147+12.7% | Added |
| Assetmark, Inc | 1,282 | $10.9K | 0.00% | +22+1.7% | Added |
| BNP Paribas Arbitrage, SA | 1,211 | $10.3K | 0.00% | +531+78.1% | Added |
| GF Fund Management Co. Ltd. | 1,126 | $9.56K | 0.00% | +202+21.9% | Added |
| Tower Research Capital LLC (TRC) | 1,081 | $9.18K | 0.00% | +156+16.9% | Added |
| GAMMA Investing LLC | 1,058 | $8.98K | 0.00% | +141+15.4% | Added |
| Citigroup Inc | 689 | $5.85K | 0.00% | +59+9.4% | Added |
| Manchester Capital Management LLC | 590 | $5.01K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 571 | $4.00K | 0.00% | +571 | New |
| HighMark Wealth Management LLC | 435 | $3.69K | 0.00% | −4,000−90.2% | Reduced |
| FMR LLC | 316 | $2.68K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 250 | $2.24K | 0.00% | +100+66.7% | Added |
| Boston Private Wealth LLC | 210 | $1.78K | 0.00% | +210 | New |
| Winch Advisory Services, LLC | 172 | $1.46K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 166 | $1.41K | 0.00% | −300−64.4% | Reduced |
| Daiwa Securities Group Inc. | 103 | $1.00K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 100 | $785 | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 61 | $518 | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 22 | $187 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 18 | $152 | 0.00% | −742−97.6% | Reduced |
| EverSource Wealth Advisors, LLC | 13 | $110 | 0.00% | −11−45.8% | Reduced |
| Ronald Blue Trust, Inc. | 11 | $93 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 10 | $85 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 6 | $51 | 0.00% | −1−14.3% | Reduced |
| Caitong International Asset Management Co., Ltd | 2 | $17 | 0.00% | −146−98.6% | Reduced |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −352,481−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −280,327−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −197,108−100.0% | Sold out |
| HighVista Strategies LLC | 0 | $0 | 0.00% | −124,430−100.0% | Sold out |
| Springhill Fund Asset Management (HK) Co Ltd | 0 | $0 | 0.00% | −116,400−100.0% | Sold out |