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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q2 2022

Institutional positions in Bicycle Therapeutics PLC as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
82
−23 vs. Q1 2022
Shares held
22.7M
+2.52M (+12.5%) vs. Q1 2022
Total value
$381.1M
−$503.4M (−56.9%) vs. Q1 2022
New holders
17
32 more added
Sold out
40
16 more reduced

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 82 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ2 2022: $381.1M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q1 2022.

Institutions holding BCYC in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Deep Track Capital, LP2,900,000$48.7M3.36%+1,044,007+56.3%Added
Logos Global Management LP1,700,000$28.5M5.23%+750,000+78.9%Added
Point72 Asset Management, L.P.1,445,000$24.2M0.11%−174,802−10.8%Reduced
Janus Henderson Group PLC1,374,489$23.1M0.02%−318,285−18.8%Reduced
RTW Investments, LP1,276,276$21.4M0.55%00.0%Unchanged
Tybourne Capital Management (HK) Ltd1,154,126$19.4M1.40%00.0%Unchanged
Paradigm Biocapital Advisors LP1,048,516$17.6M3.51%+1,048,516New
Samlyn Capital, LLC1,040,239$17.5M0.35%+613,696+143.9%Added
SV Health Investors, LLC907,032$15.2M34.74%−10,186−1.1%Reduced
Eventide Asset Management, LLC853,800$14.3M0.31%−409,671−32.4%Reduced
Candriam Luxembourg S.C.A.834,676$14.0M0.12%+834,676New
Morgan Stanley821,204$13.8M0.00%+733,287+834.1%Added
FMR LLC708,080$11.9M0.00%−95,668−11.9%Reduced
First Light Asset Management, LLC704,282$11.8M1.38%−185,892−20.9%Reduced
Sio Capital Management, LLC688,989$11.6M4.55%+636,201+1,205.2%Added
AXA S.A.463,027$7.77M0.03%+317,773+218.8%Added
Price T Rowe Associates Inc421,261$7.07M0.00%−264,615−38.6%Reduced
Two Sigma Advisers, LP415,200$6.97M0.02%+286,400+222.4%Added
Verition Fund Management LLC399,023$6.70M0.15%+264,819+197.3%Added
Two Sigma Investments, LP380,654$6.39M0.02%+203,332+114.7%Added
Millennium Management LLC333,701$5.60M0.01%+170,334+104.3%Added
Citadel Advisors LLC243,334$4.08M0.01%+243,334New
BlackRock Inc.191,106$3.21M0.00%+977+0.5%Added
Pura Vida Investments, LLC183,121$3.07M0.49%+183,121New
ExodusPoint Capital Management, LP182,125$3.06M0.04%+182,125New
Goldman Sachs Group Inc154,326$2.59M0.00%−8,939−5.5%Reduced
Renaissance Technologies LLC153,200$2.57M0.00%+88,801+137.9%Added
HighVista Strategies LLC151,207$2.54M1.53%+132,909+726.4%Added
Alliancebernstein L.P.132,306$2.22M0.00%+132,306New
DAFNA Capital Management LLC131,200$2.20M0.60%+78,000+146.6%Added
Handelsbanken Fonder AB130,000$2.18M0.01%00.0%Unchanged
Qube Research & Technologies Ltd124,696$2.09M0.02%+115,890+1,316.0%Added
Voloridge Investment Management, LLC123,050$2.06M0.01%+123,050New
Allianz Asset Management GmbH84,485$1.42M0.00%+84,485New
Bellevue Group AG84,400$1.42M0.02%+47,900+131.2%Added
JPMorgan Chase & Co83,458$1.40M0.00%+73,555+742.8%Added
Marshall Wace, LLP80,123$1.34M0.00%+69,504+654.5%Added
Parkman Healthcare Partners LLC60,426$1.01M0.37%+3,131+5.5%Added
UBS Oconnor LLC57,625$967.0K0.01%+57,625New
Acadian Asset Management LLC56,909$954.0K0.00%+20,950+58.3%Added
Harbor Capital Advisors, Inc.51,027$856.0K0.65%+22,085+76.3%Added
Victory Capital Management Inc33,412$561.0K0.00%−518,003−93.9%Reduced
SG Americas Securities, LLC30,328$509.0K0.01%−51−0.2%Reduced
Manufacturers Life Insurance Company, The25,136$431.3K0.00%+5,603+28.7%Added
Eagle Health Investments LP23,500$394.0K0.09%+23,500New
AtonRa Partners23,019$386.0K0.35%+6,394+38.5%Added
Schonfeld Strategic Advisors LLC21,300$358.0K0.00%+13,300+166.3%Added
Tekla Capital Management LLC20,065$337.0K0.01%+9,979+98.9%Added
Ensign Peak Advisors, Inc18,260$306.0K0.00%00.0%Unchanged
Alps Advisors Inc17,590$295.0K0.00%+17,590New
State Street Corp17,474$293.0K0.00%+6,787+63.5%Added
Bank of America Corp17,297$290.0K0.00%+14,187+456.2%Added
TD Asset Management Inc15,586$262.0K0.00%−13,500−46.4%Reduced
Erste Asset Management GmbH14,000$240.2K0.01%00.0%Unchanged
Man Group plc–$233.0K0.00%–New
UBS Group AG12,966$218.0K0.00%+4,082+45.9%Added
DekaBank Deutsche Girozentrale13,200$214.0K0.00%00.0%Unchanged
Geode Capital Management, LLC11,133$186.0K0.00%00.0%Unchanged
Trexquant Investment LP10,899$183.0K0.01%+10,899New
Woodstock Corp10,320$173.0K0.02%00.0%Unchanged
Legal & General Group Plc9,133$154.0K0.00%−2,133−18.9%Reduced
Virtus ETF Advisers LLC7,946$133.0K0.05%+4,959+166.0%Added
HighMark Wealth Management LLC4,235$71.0K0.06%00.0%Unchanged
Quantbot Technologies LP3,612$60.0K0.01%+3,612New
Cutler Group LP2,500$41.0K0.01%−50−2.0%Reduced
Tower Research Capital LLC (TRC)1,079$18.0K0.00%+683+172.5%Added
Advisor Group Holdings, Inc.950$16.0K0.00%−3,089−76.5%Reduced
Citigroup Inc589$10.0K0.00%−159−21.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)535$9.00K0.00%00.0%Unchanged
High Net Worth Advisory Group LLC500$8.00K0.00%00.0%Unchanged
Captrust Financial Advisors354$6.00K0.00%00.0%Unchanged
US Bancorp383$6.00K0.00%+149+63.7%Added
BNP Paribas Arbitrage, SA333$5.59K0.00%+333New
Royal Bank of Canada190$3.00K0.00%−57−23.1%Reduced
Rockefeller Capital Management L.P.213$3.00K0.00%+48+29.1%Added
Daiwa Securities Group Inc.58$1.00K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.40$1.00K0.00%00.0%Unchanged
Zullo Investment Group, Inc.50$1.00K0.00%00.0%Unchanged
Crewe Advisors LLC83$1.00K0.00%+83New
Meeder Asset Management Inc2$00.00%00.0%Unchanged
Parallel Advisors, LLC5$00.00%00.0%Unchanged
Wells Fargo & Company1$00.00%+1New
Loomis Sayles & Co L P0$00.00%−643,775−100.0%Sold out
Frazier Life Sciences Management, L.P.0$00.00%−603,521−100.0%Sold out
Great Point Partners LLC0$00.00%−550,592−100.0%Sold out
EcoR1 Capital, LLC0$00.00%−547,453−100.0%Sold out
Ikarian Capital, LLC0$00.00%−478,784−100.0%Sold out
Driehaus Capital Management LLC0$00.00%−229,290−100.0%Sold out
Opaleye Management Inc.0$00.00%−175,000−100.0%Sold out
Sofinnova Investments, Inc.0$00.00%−163,559−100.0%Sold out
Dorsey Wright & Associates0$00.00%−126,982−100.0%Sold out
Altium Capital Management LP0$00.00%−120,000−100.0%Sold out
Ghost Tree Capital, LLC0$00.00%−100,000−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−46,770−100.0%Sold out
LMR Partners LLP0$00.00%−40,283−100.0%Sold out
Fred Alger Management, LLC0$00.00%−39,246−100.0%Sold out
Caption Management, LLC0$00.00%−38,013−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−36,164−100.0%Sold out
Stifel Financial Corp0$00.00%−31,746−100.0%Sold out
Jump Financial, LLC0$00.00%−28,176−100.0%Sold out