Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Bicycle Therapeutics PLC as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 110
- +15 vs. Q1 2025
- Shares held
- 41.2M
- −534.9K (−1.3%) vs. Q1 2025
- Total value
- $286.3M
- −$68.0M (−19.2%) vs. Q1 2025
- New holders
- 29
- 37 more added
- Sold out
- 14
- 21 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 10,885,357 | $75.7M | 0.73% | 00.0% | Unchanged |
| FCPM III Services B.V. | 3,452,330 | $24.0M | 6.50% | 00.0% | Unchanged |
| Armistice Capital, LLC | 2,800,000 | $19.5M | 0.74% | +128,000+4.8% | Added |
| Westfield Capital Management Co LP | 2,780,491 | $19.3M | 0.08% | +123,186+4.6% | Added |
| Siren, L.L.C. | 2,012,752 | $14.0M | 0.72% | +200,000+11.0% | Added |
| Point72 Asset Management, L.P. | 1,772,600 | $12.3M | 0.03% | −1,919,469−52.0% | Reduced |
| Price T Rowe Associates Inc | 1,468,393 | $10.2M | 0.00% | −68,191−4.4% | Reduced |
| Millennium Management LLC | 1,443,619 | $10.0M | 0.01% | +990,191+218.4% | Added |
| Long Focus Capital Management, LLC | 1,317,293 | $9.16M | 0.59% | +23,540+1.8% | Added |
| Deep Track Capital, LP | 1,203,244 | $8.36M | 0.27% | +436,228+56.9% | Added |
| Candriam Luxembourg S.C.A. | 1,172,387 | $8.15M | 0.05% | −32,820−2.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,041,456 | $7.24M | 0.02% | −178,232−14.6% | Reduced |
| Morgan Stanley | 1,037,153 | $7.21M | 0.00% | +37,316+3.7% | Added |
| Tybourne Capital Management (HK) Ltd | 993,743 | $6.91M | 20.00% | +417,400+72.4% | Added |
| Bank of America Corp | 830,634 | $5.77M | 0.00% | +267,075+47.4% | Added |
| Principal Financial Group Inc | 697,267 | $4.85M | 0.00% | +66,007+10.5% | Added |
| Acadian Asset Management LLC | 698,501 | $4.84M | 0.01% | +572,439+454.1% | Added |
| Jefferies Financial Group Inc. | 461,100 | $3.20M | 0.05% | +52,211+12.8% | Added |
| Woodline Partners LP | 362,325 | $2.52M | 0.01% | −1,426−0.4% | Reduced |
| Renaissance Technologies LLC | 318,400 | $2.21M | 0.00% | +16,900+5.6% | Added |
| Platinum Investment Management Ltd | 285,381 | $1.98M | 0.13% | −2,218−0.8% | Reduced |
| AXA S.A. | 280,152 | $1.95M | 0.01% | −273,530−49.4% | Reduced |
| Silvercrest Asset Management Group LLC | 265,693 | $1.85M | 0.01% | 00.0% | Unchanged |
| BlackRock, Inc. | 264,348 | $1.84M | 0.00% | −58,528−18.1% | Reduced |
| Palo Alto Investors LP | 248,934 | $1.73M | 0.37% | 00.0% | Unchanged |
| Eversept Partners, LP | 211,469 | $1.47M | 0.15% | +211,469 | New |
| Handelsbanken Fonder AB | 200,000 | $1.39M | 0.00% | −15,900−7.4% | Reduced |
| TD Asset Management Inc | 193,092 | $1.34M | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 174,910 | $1.21M | 0.00% | +39,252+28.9% | Added |
| Pinnacle Associates Ltd | 171,953 | $1.20M | 0.02% | −42,325−19.8% | Reduced |
| UBS Oconnor LLC | 143,800 | $999.4K | 0.03% | −4,922−3.3% | Reduced |
| Manufacturers Life Insurance Company, The | 140,492 | $976.4K | 0.00% | +2,243+1.6% | Added |
| Citadel Advisors LLC | 139,467 | $969.3K | 0.00% | +9,397+7.2% | Added |
| Harbor Capital Advisors, Inc. | 138,661 | $964.0K | 0.04% | −9,468−6.4% | Reduced |
| Janney Montgomery Scott LLC | 100,291 | $697.0K | 0.00% | +100,291 | New |
| Soleus Capital Management, L.P. | 100,000 | $695.0K | 0.05% | +100,000 | New |
| Cubist Systematic Strategies, LLC | 87,717 | $609.6K | 0.01% | +40,468+85.6% | Added |
| Monimus Capital Management, LP | 85,224 | $592.3K | 0.48% | +85,224 | New |
| Moore Capital Management, LP | 75,000 | $521.3K | 0.01% | +25,000+50.0% | Added |
| Rangeley Capital, LLC | 75,000 | $521.3K | 0.66% | +75,000 | New |
| Two Sigma Advisers, LP | 70,200 | $487.9K | 0.00% | +70,200 | New |
| Nan Fung Group Holdings Ltd | 68,943 | $479.2K | 0.76% | 00.0% | Unchanged |
| State Street Corp | 65,997 | $458.7K | 0.00% | −19,656−22.9% | Reduced |
| DAFNA Capital Management LLC | 64,492 | $448.2K | 0.12% | −16,307−20.2% | Reduced |
| Two Sigma Investments, LP | 56,198 | $390.6K | 0.00% | +56,198 | New |
| Goldman Sachs Group Inc | 52,265 | $363.2K | 0.00% | +27,073+107.5% | Added |
| Dynamic Technology Lab Private Ltd | 45,950 | $320.0K | 0.04% | +45,950 | New |
| Skandinaviska Enskilda Banken AB (publ) | 42,729 | $296.5K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 40,412 | $280.9K | 0.00% | +19,035+89.0% | Added |
| Paloma Partners Management Co | 39,250 | $272.8K | 0.06% | +39,250 | New |
| UBS Group AG | 33,375 | $232.0K | 0.00% | −39,327−54.1% | Reduced |
| DekaBank Deutsche Girozentrale | 30,000 | $211.0K | 0.00% | 00.0% | Unchanged |
| Man Group plc | 28,675 | $199.3K | 0.00% | +28,675 | New |
| UBS Asset Management Americas Inc | 27,300 | $189.7K | 0.00% | +22,200+435.3% | Added |
| Susquehanna International Group, LLP | 26,567 | $184.6K | 0.00% | +26,567 | New |
| Alps Advisors Inc | 25,757 | $179.0K | 0.00% | +25,757 | New |
| Woodstock Corp | 23,927 | $166.3K | 0.02% | −1,054−4.2% | Reduced |
| Tocqueville Asset Management L.P. | 22,900 | $159.2K | 0.00% | +4,600+25.1% | Added |
| Jane Street Group, LLC | 22,607 | $157.1K | 0.00% | +22,607 | New |
| Quadrature Capital Ltd | 17,738 | $122.9K | 0.00% | +17,738 | New |
| Jump Financial, LLC | 16,740 | $116.3K | 0.00% | +16,740 | New |
| Portland Investment Counsel Inc. | 15,000 | $108.6K | 0.03% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 15,402 | $107.0K | 0.00% | +15,402 | New |
| Erste Asset Management GmbH | 14,000 | $101.4K | 0.00% | 00.0% | Unchanged |
| State of Tennessee, Treasury Department | 14,382 | $100.0K | 0.00% | +14,382 | New |
| Cerity Partners LLC | 14,350 | $99.7K | 0.00% | +1,000+7.5% | Added |
| Horizon Kinetics Asset Management LLC | 13,792 | $95.9K | 0.00% | −604−4.2% | Reduced |
| Graham Capital Management, L.P. | 13,102 | $91.1K | 0.00% | +13,102 | New |
| The PNC Financial Services Group, Inc. | 13,080 | $90.9K | 0.00% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 12,304 | $85.5K | 0.00% | +12,304 | New |
| Squarepoint Ops LLC | 11,874 | $82.5K | 0.00% | +11,874 | New |
| Crossmark Global Holdings, Inc. | 11,389 | $79.2K | 0.00% | −11−0.1% | Reduced |
| Virtus Investment Advisers, Inc. | 10,821 | $75.2K | 0.03% | +2,659+32.6% | Added |
| SEI Investments Co | 10,637 | $73.9K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 10,362 | $72.0K | 0.00% | −7,578−42.2% | Reduced |
| Ausdal Financial Partners, Inc. | 10,000 | $69.5K | 0.00% | +10,000 | New |
| Federation des caisses Desjardins du Quebec | 9,603 | $66.8K | 0.00% | +9,542+15,642.6% | Added |
| China Universal Asset Management Co., Ltd. | 8,866 | $61.6K | 0.01% | +33+0.4% | Added |
| JPMorgan Chase & Co | 7,637 | $53.1K | 0.00% | +593+8.4% | Added |
| Tower Research Capital LLC (TRC) | 4,159 | $28.9K | 0.00% | +3,078+284.7% | Added |
| Barclays PLC | 3,476 | $24.2K | 0.00% | +168+5.1% | Added |
| Rhumbline Advisers | 3,005 | $20.9K | 0.00% | +1,701+130.4% | Added |
| Assetmark, Inc | 2,073 | $14.4K | 0.00% | +791+61.7% | Added |
| Natixis | 1,947 | $13.9K | 0.00% | −179−8.4% | Reduced |
| Raymond James Financial Inc | 1,933 | $13.4K | 0.00% | +1,933 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,705 | $11.8K | 0.00% | +241+16.5% | Added |
| Caitong International Asset Management Co., Ltd | 1,517 | $10.5K | 0.01% | +1,515+75,750.0% | Added |
| GAMMA Investing LLC | 1,488 | $10.3K | 0.00% | +430+40.6% | Added |
| Clearstead Advisors, LLC | 1,393 | $9.68K | 0.00% | +1,393 | New |
| Group One Trading, L.P. | 1,294 | $8.99K | 0.00% | +1,128+679.5% | Added |
| Simplex Trading, LLC | 1,241 | $8.00K | 0.00% | +670+117.3% | Added |
| GF Fund Management Co. Ltd. | 1,126 | $7.83K | 0.00% | 00.0% | Unchanged |
| Skopos Labs, Inc. | 923 | $6.42K | 0.00% | +923 | New |
| Citigroup Inc | 913 | $6.34K | 0.00% | +224+32.5% | Added |
| Manchester Capital Management LLC | 590 | $4.10K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 530 | $3.68K | 0.00% | −681−56.2% | Reduced |
| HighMark Wealth Management LLC | 435 | $3.02K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 316 | $2.20K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 250 | $1.81K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 200 | $1.39K | 0.00% | +200 | New |