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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
101
+17 vs. Q2 2023
Shares held
32.4M
+8.21M (+33.9%) vs. Q2 2023
Total value
$651.3M
+$34.0M (+5.5%) vs. Q2 2023
New holders
24
36 more added
Sold out
7
23 more reduced

1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 101 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ3 2023: $651.3M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2023.

Institutions holding BCYC in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Paradigm Biocapital Advisors LP3,642,307$73.2M4.99%+1,656,877+83.5%Added
Deep Track Capital, LP3,490,506$70.1M2.72%+671,461+23.8%Added
First Light Asset Management, LLC2,070,853$41.6M3.95%+331,404+19.1%Added
Jefferies Financial Group Inc.1,948,000$39.1M0.98%00.0%Unchanged
Morgan Stanley1,621,749$32.6M0.00%+182,182+12.7%Added
Point72 Asset Management, L.P.1,299,500$26.1M0.09%+821,500+171.9%Added
Braidwell LP1,289,872$25.9M0.82%+1,289,872New
Tybourne Capital Management (HK) Ltd1,281,820$25.8M3.60%00.0%Unchanged
Candriam Luxembourg S.C.A.1,253,261$25.2M0.21%−20,000−1.6%Reduced
Polar Capital Holdings Plc1,011,500$20.3M0.15%+252,000+33.2%Added
Suvretta Capital Management, LLC1,010,976$20.3M1.10%+1,010,976New
Armistice Capital, LLC1,000,000$20.1M0.60%+124,000+14.2%Added
Verition Fund Management LLC916,382$18.4M0.25%+237,370+35.0%Added
Janus Henderson Group PLC910,930$18.3M0.01%−370,394−28.9%Reduced
Baker Bros. Advisors LP843,814$17.0M0.10%00.0%Unchanged
Ra Capital Management, L.P.800,000$16.1M0.32%+800,000New
Sio Capital Management, LLC796,933$16.0M4.96%−171,738−17.7%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.640,882$12.9M0.04%+131,572+25.8%Added
Price T Rowe Associates Inc593,053$11.9M0.00%+295,768+99.5%Added
AXA S.A.575,067$11.6M0.04%+21,435+3.9%Added
Deerfield Management Company, L.P. (Series C)448,753$9.02M0.20%+448,753New
Nomura Holdings Inc400,000$8.04M0.09%00.0%Unchanged
Camber Capital Management LP400,000$8.04M0.29%+400,000New
Soleus Capital Management, L.P.391,800$7.87M0.79%−20,000−4.9%Reduced
Millennium Management LLC315,093$6.33M0.01%+236,334+300.1%Added
Platinum Investment Management Ltd285,479$5.74M0.22%+285,479New
FMR LLC266,347$5.35M0.00%−20,800−7.2%Reduced
Rubric Capital Management LP205,423$4.13M0.17%00.0%Unchanged
BlackRock Inc.194,084$3.90M0.00%+12,976+7.2%Added
Kennedy Capital Management, Inc.156,705$3.15M0.08%+33,517+27.2%Added
Citadel Advisors LLC135,697$2.73M0.00%+24,541+22.1%Added
Handelsbanken Fonder AB134,500$2.70M0.02%00.0%Unchanged
Parkman Healthcare Partners LLC122,721$2.47M0.45%−49,564−28.8%Reduced
DAFNA Capital Management LLC122,200$2.45M0.76%00.0%Unchanged
Voya Investment Management LLC113,355$2.28M0.00%+24,985+28.3%Added
Deutsche Bank AG96,370$1.94M0.00%+88,000+1,051.4%Added
Legal & General Group Plc92,463$1.86M0.00%+12,207+15.2%Added
HighVista Strategies LLC92,434$1.86M0.86%00.0%Unchanged
Renaissance Technologies LLC82,000$1.65M0.00%+11,100+15.7%Added
TD Asset Management Inc81,786$1.64M0.00%+58,200+246.8%Added
Group One Trading, L.P.81,226$1.63M0.06%−2,741−3.3%Reduced
UBS Oconnor LLC77,902$1.57M0.03%00.0%Unchanged
Trexquant Investment LP70,719$1.42M0.04%+70,719New
Two Sigma Advisers, LP70,700$1.42M0.00%−68,700−49.3%Reduced
JPMorgan Chase & Co68,499$1.38M0.00%−27,652−28.8%Reduced
Susquehanna International Group, LLP65,681$1.32M0.00%+3,017+4.8%Added
Cubist Systematic Strategies, LLC65,545$1.32M0.02%+40,848+165.4%Added
AlphaCentric Advisors LLC58,500$1.18M0.67%+58,500New
Schonfeld Strategic Advisors LLC52,100$1.05M0.01%−14,000−21.2%Reduced
Ghisallo Capital Management LLC50,000$1.00M0.10%+50,000New
Jane Street Group, LLC49,374$991.9K0.00%+49,374New
Bellevue Group AG39,200$787.5K0.01%+14,200+56.8%Added
Fishman Jay A Ltd37,500$753.4K0.10%+17,000+82.9%Added
Jump Financial, LLC37,067$744.7K0.03%+18,906+104.1%Added
Manufacturers Life Insurance Company, The36,092$725.1K0.00%+10,956+43.6%Added
State Street Corp35,866$720.5K0.00%+27,200+313.9%Added
Simplex Trading, LLC31,534$633.0K0.02%−34,909−52.5%Reduced
DekaBank Deutsche Girozentrale30,000$584.0K0.00%00.0%Unchanged
Alpha DNA Investment Management LLC27,957$561.7K0.36%+27,957New
AE Wealth Management LLC24,773$497.7K0.00%+24,773New
Mach-1 Financial Group, Inc.24,701$496.2K0.21%+24,701New
Harbor Capital Advisors, Inc.24,210$486.4K0.10%+3,165+15.0%Added
Two Sigma Investments, LP22,930$460.7K0.00%−29,696−56.4%Reduced
Maven Securities LTD22,500$452.0K0.05%+22,500New
Woodstock Corp20,553$412.9K0.05%00.0%Unchanged
Geode Capital Management, LLC17,144$344.4K0.00%00.0%Unchanged
Allianz Asset Management GmbH17,000$341.5K0.00%−3,400−16.7%Reduced
Engineers Gate Manager LP16,076$323.0K0.01%+16,076New
Horizon Kinetics Asset Management LLC15,000$301.4K0.01%00.0%Unchanged
Erste Asset Management GmbH14,000$283.2K0.00%00.0%Unchanged
AtonRa Partners11,588$232.8K0.49%−2,631−18.5%Reduced
UBS Group AG11,305$227.1K0.00%−1,307−10.4%Reduced
Tower Research Capital LLC (TRC)9,867$198.2K0.01%+7,447+307.7%Added
Bank of America Corp6,296$126.5K0.00%−236−3.6%Reduced
Exchange Traded Concepts, LLC5,021$100.9K0.00%−255−4.8%Reduced
Sandia Investment Management LP5,000$100.5K0.03%+5,000New
BIT Capital GmbH4,850$97.4K0.01%00.0%Unchanged
HighMark Wealth Management LLC4,435$89.1K0.07%+200+4.7%Added
Virtus ETF Advisers LLC3,705$74.4K0.05%−369−9.1%Reduced
Advisor Group Holdings, Inc.3,348$67.3K0.00%+1,028+44.3%Added
Natixis2,768$55.1K0.00%−7−0.3%Reduced
Cutler Group LP2,400$48.0K0.01%−3,652−60.3%Reduced
First Manhattan Co2,200$44.2K0.00%+2,200New
BluePath Capital Management, LLC1,534$30.8K0.03%+1,534New
Aquatic Capital Management LLC900$18.0K0.00%+900New
China Universal Asset Management Co., Ltd.679$13.6K0.00%+340+100.3%Added
Royal Bank of Canada535$11.0K0.00%+153+40.1%Added
Citigroup Inc532$10.7K0.00%−71−11.8%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)514$10.3K0.00%−170−24.9%Reduced
Comerica Bank450$9.04K0.00%+450New
Rhumbline Advisers410$8.23K0.00%+30+7.9%Added
BNP Paribas Arbitrage, SA348$6.99K0.00%+159+84.1%Added
Macroview Investment Management LLC335$6.73K0.01%+335New
Quantbot Technologies LP300$6.03K0.00%+300New
Raleigh Capital Management Inc.185$3.72K0.00%00.0%Unchanged
Barclays PLC168$3.38K0.00%+84+100.0%Added
Highline Wealth Partners LLC110$2.21K0.00%+110New
Daiwa Securities Group Inc.103$2.00K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.40$8040.00%00.0%Unchanged
Bell Investment Advisors, Inc24$4830.00%−13−35.1%Reduced