Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 98
- −11 vs. Q4 2025
- Shares held
- 37.5M
- −1.71M (−4.4%) vs. Q4 2025
- Total value
- $173.6M
- −$103.3M (−37.3%) vs. Q4 2025
- New holders
- 15
- 43 more added
- Sold out
- 26
- 16 more reduced
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 10,885,357 | $50.5M | 0.29% | 00.0% | Unchanged |
| FCPM III Services B.V. | 3,468,430 | $16.1M | 2.23% | 00.0% | Unchanged |
| Armistice Capital, LLC | 3,398,000 | $15.8M | 0.52% | +162,000+5.0% | Added |
| Long Focus Capital Management, LLC | 3,310,687 | $15.4M | 0.67% | +1,677,596+102.7% | Added |
| Acadian Asset Management LLC | 1,968,025 | $9.11M | 0.01% | +296,767+17.8% | Added |
| Siren, L.L.C. | 1,560,882 | $7.24M | 0.20% | −451,870−22.5% | Reduced |
| GSK plc | 1,529,561 | $7.10M | 1.18% | 00.0% | Unchanged |
| Principal Financial Group Inc | 1,174,625 | $5.45M | 0.00% | +26,353+2.3% | Added |
| Price T Rowe Associates Inc | 1,028,243 | $4.77M | 0.00% | −143,544−12.3% | Reduced |
| Renaissance Technologies LLC | 979,300 | $4.54M | 0.01% | +412,700+72.8% | Added |
| Morgan Stanley | 618,327 | $2.87M | 0.00% | +153,105+32.9% | Added |
| Schroder Investment Management Group | 615,833 | $2.67M | 0.00% | +31,063+5.3% | Added |
| Diadema Partners LP | 476,424 | $2.21M | 0.91% | +476,424 | New |
| Birchview Capital, LP | 463,599 | $2.15M | 1.22% | +899+0.2% | Added |
| Silvercrest Asset Management Group LLC | 428,684 | $1.99M | 0.01% | −48,292−10.1% | Reduced |
| Marshall Wace, LLP | 377,335 | $1.75M | 0.00% | +338,540+872.6% | Added |
| Citadel Advisors LLC | 377,085 | $1.75M | 0.00% | +105,702+38.9% | Added |
| Qube Research & Technologies Ltd | 308,617 | $1.43M | 0.00% | +308,617 | New |
| Millennium Management LLC | 283,986 | $1.32M | 0.00% | −42,640−13.1% | Reduced |
| BlackRock, Inc. | 278,992 | $1.29M | 0.00% | −53,897−16.2% | Reduced |
| Moore Capital Management, LP | 275,000 | $1.28M | 0.05% | 00.0% | Unchanged |
| Rangeley Capital, LLC | 232,260 | $1.08M | 1.17% | +100,260+76.0% | Added |
| Jane Street Group, LLC | 218,115 | $1.01M | 0.00% | +154,925+245.2% | Added |
| Palo Alto Investors LP | 201,890 | $936.8K | 0.14% | −19,181−8.7% | Reduced |
| Eversept Partners, LP | 190,715 | $884.9K | 0.06% | +11,800+6.6% | Added |
| Pinnacle Associates Ltd | 185,410 | $860.3K | 0.01% | −5,070−2.7% | Reduced |
| Platinum Investment Management Ltd | 184,603 | $856.6K | 0.22% | 00.0% | Unchanged |
| Flax Pond Capital, LLC | 176,136 | $817.3K | 0.66% | +2,503+1.4% | Added |
| Two Sigma Investments, LP | 164,800 | $764.7K | 0.00% | +32,768+24.8% | Added |
| Point72 Asset Management, L.P. | 130,422 | $605.2K | 0.00% | +53,643+69.9% | Added |
| Manufacturers Life Insurance Company, The | 127,863 | $593.3K | 0.00% | 00.0% | Unchanged |
| Persistent Asset Partners Ltd | 120,437 | $558.8K | 0.22% | +120,437 | New |
| Peapod Lane Capital LLC | 121,106 | $550.2K | 0.45% | +121,106 | New |
| Marex Group plc | 115,000 | $533.6K | 0.01% | +36,594+46.7% | Added |
| Goldman Sachs Group Inc | 110,147 | $511.1K | 0.00% | +85,415+345.4% | Added |
| XTX Topco Ltd | 106,392 | $493.7K | 0.01% | +58,718+123.2% | Added |
| TD Asset Management Inc | 91,992 | $426.8K | 0.00% | −56,000−37.8% | Reduced |
| ADAR1 Capital Management, LLC | 71,298 | $330.8K | 0.02% | +71,298 | New |
| DAFNA Capital Management LLC | 64,492 | $299.2K | 0.07% | 00.0% | Unchanged |
| EntryPoint Capital, LLC | 63,906 | $296.5K | 0.09% | +63,906 | New |
| Man Group plc | 63,305 | $293.7K | 0.00% | +20,445+47.7% | Added |
| Axq Capital, LP | 63,134 | $292.9K | 0.04% | +63,134 | New |
| State of Tennessee, Treasury Department | 61,153 | $283.8K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 52,784 | $244.9K | 0.00% | +3,728+7.6% | Added |
| Jump Financial, LLC | 52,544 | $243.8K | 0.00% | +21,544+69.5% | Added |
| HRT Financial LP | 45,915 | $213.0K | 0.00% | +45,915 | New |
| Alps Advisors Inc | 40,651 | $188.6K | 0.00% | −344−0.8% | Reduced |
| Susquehanna International Group, LLP | 37,888 | $175.8K | 0.00% | −70,535−65.1% | Reduced |
| Virtus Investment Advisers, Inc. | 36,601 | $169.8K | 0.05% | +892+2.5% | Added |
| Engineers Gate Manager LP | 35,400 | $164.3K | 0.00% | +11,353+47.2% | Added |
| UBS Group AG | 32,159 | $149.2K | 0.00% | +6,483+25.2% | Added |
| State Street Corp | 30,512 | $141.6K | 0.00% | −39,666−56.5% | Reduced |
| Woodstock Corp | 29,146 | $135.2K | 0.01% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 26,842 | $125.0K | 0.01% | +26,842 | New |
| Aquatic Capital Management LLC | 26,160 | $121.4K | 0.00% | +7,343+39.0% | Added |
| Geode Capital Management, LLC | 25,129 | $116.6K | 0.00% | 00.0% | Unchanged |
| R Squared Ltd | 21,057 | $97.7K | 0.05% | +21,057 | New |
| State of New Jersey Common Pension Fund D | 20,105 | $93.3K | 0.00% | 00.0% | Unchanged |
| Vontobel Holding Ltd. | 20,000 | $92.8K | 0.00% | +10,000+100.0% | Added |
| Invesco Ltd. | 15,067 | $69.9K | 0.00% | +4,975+49.3% | Added |
| Portland Investment Counsel Inc. | 15,000 | $69.6K | 0.02% | 00.0% | Unchanged |
| Stifel Financial Corp | 14,687 | $68.1K | 0.00% | +14,687 | New |
| Royal Bank of Canada | 14,470 | $67.0K | 0.00% | +3,788+35.5% | Added |
| Forefront Analytics, LLC | 14,394 | $66.8K | 0.06% | +1,023+7.7% | Added |
| Federation des caisses Desjardins du Quebec | 14,302 | $66.5K | 0.00% | 00.0% | Unchanged |
| 49 Wealth Management, LLC | 14,317 | $66.4K | 0.00% | +14,317 | New |
| Cerity Partners LLC | 13,570 | $63.0K | 0.00% | +220+1.6% | Added |
| Horizon Kinetics Asset Management LLC | 13,188 | $61.2K | 0.00% | −604−4.4% | Reduced |
| Erste Asset Management GmbH | 14,000 | $60.8K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 12,571 | $58.3K | 0.00% | +1,400+12.5% | Added |
| Crossmark Global Holdings, Inc. | 11,408 | $52.9K | 0.00% | +9+0.1% | Added |
| Pinnacle Wealth Management Advisory Group, LLC | 10,985 | $51.0K | 0.00% | +985+9.9% | Added |
| Two Sigma Securities, LLC | 10,879 | $50.5K | 0.01% | +10,879 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 10,116 | $46.9K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 9,873 | $42.8K | 0.00% | −8,482−46.2% | Reduced |
| Legal & General Group Plc | 9,054 | $39.2K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 8,222 | $38.1K | 0.00% | +682+9.0% | Added |
| FNY Investment Advisers, LLC | 7,557 | $35.0K | 0.02% | +71+0.9% | Added |
| Natixis | 4,645 | $21.2K | 0.00% | 00.0% | Unchanged |
| Assetmark, Inc | 4,218 | $19.6K | 0.00% | +590+16.3% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,417 | $11.2K | 0.00% | +169+7.5% | Added |
| Barclays PLC | 2,357 | $10.9K | 0.00% | +1,795+319.4% | Added |
| Tower Research Capital LLC (TRC) | 1,966 | $9.12K | 0.00% | +298+17.9% | Added |
| Citigroup Inc | 1,295 | $6.01K | 0.00% | +4+0.3% | Added |
| GAMMA Investing LLC | 1,257 | $5.83K | 0.00% | −129−9.3% | Reduced |
| GF Fund Management Co. Ltd. | 1,032 | $4.79K | 0.00% | +123+13.5% | Added |
| BNP Paribas Arbitrage, SA | 1,016 | $4.71K | 0.00% | −100−9.0% | Reduced |
| Jones Financial Companies LLLP | 500 | $2.15K | 0.00% | +250+100.0% | Added |
| HighMark Wealth Management LLC | 435 | $2.02K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 200 | $928 | 0.00% | 00.0% | Unchanged |
| Winch Advisory Services, LLC | 172 | $798 | 0.00% | 00.0% | Unchanged |
| Basecamp Wealth Advisors LLC | 167 | $775 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 10 | $46 | 0.00% | +10 | New |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 9 | $42 | 0.00% | −134,680−100.0% | Reduced |
| SBI Securities Co., Ltd. | 6 | $28 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 5 | $23 | 0.00% | 00.0% | Unchanged |
| Caitlin John, LLC | 2 | $9 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 1 | $5 | 0.00% | +1 | New |
| Westfield Capital Management Co LP | 0 | $0 | 0.00% | −3,016,026−100.0% | Sold out |
| Candriam Luxembourg S.C.A. | 0 | $0 | 0.00% | −1,192,279−100.0% | Sold out |