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Bicycle Therapeutics PLC

BCYC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001761612

In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Bicycle Therapeutics PLC as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
−4 vs. Q4 2023
Shares held
30.5M
−879.2K (−2.8%) vs. Q4 2023
Total value
$759.1M
+$192.0M (+33.8%) vs. Q4 2023
New holders
13
30 more added
Sold out
17
32 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 95 institutions
Q1 2021: 39 institutionsQ2 2021: 54 institutionsQ3 2021: 69 institutionsQ4 2021: 101 institutionsQ1 2022: 105 institutionsQ2 2022: 82 institutionsQ3 2022: 79 institutionsQ4 2022: 87 institutionsQ1 2023: 89 institutionsQ2 2023: 85 institutionsQ3 2023: 101 institutionsQ4 2023: 101 institutionsQ1 2024: 95 institutionsQ2 2024: 107 institutionsQ3 2024: 105 institutionsQ4 2024: 97 institutionsQ1 2025: 95 institutionsQ2 2025: 110 institutionsQ3 2025: 99 institutionsQ4 2025: 109 institutionsQ1 2026: 98 institutionsQ2 2026: 103 institutions
Value heldQ1 2024: $759.1M
Q1 2021: $341.2MQ2 2021: $376.9MQ3 2021: $591.1MQ4 2021: $1.31BQ1 2022: $884.5MQ2 2022: $381.1MQ3 2022: $538.0MQ4 2022: $695.9MQ1 2023: $498.9MQ2 2023: $618.5MQ3 2023: $651.3MQ4 2023: $567.4MQ1 2024: $759.1MQ2 2024: $804.0MQ3 2024: $915.3MQ4 2024: $586.5MQ1 2025: $354.4MQ2 2025: $286.3MQ3 2025: $285.6MQ4 2025: $276.9MQ1 2026: $173.6MQ2 2026: $157.9M
Institutions holding BCYC and their total value by quarter
QuarterHoldersValue
Q2 2026103$157.9M
Q1 202698$173.6M
Q4 2025109$276.9M
Q3 202599$285.6M
Q2 2025110$286.3M
Q1 202595$354.4M
Q4 202497$586.5M
Q3 2024105$915.3M
Q2 2024107$804.0M
Q1 202495$759.1M
Q4 2023101$567.4M
Q3 2023101$651.3M
Q2 202385$618.5M
Q1 202389$498.9M
Q4 202287$695.9M
Q3 202279$538.0M
Q2 202282$381.1M
Q1 2022105$884.5M
Q4 2021101$1.31B
Q3 202169$591.1M
Q2 202154$376.9M
Q1 202139$341.2M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q4 2023.

Institutions holding BCYC in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP4,942,823$123.1M1.54%+3,152,433+176.1%Added
Deep Track Capital, LP3,490,506$86.9M2.50%00.0%Unchanged
Paradigm Biocapital Advisors LP3,246,759$80.8M2.85%−460,242−12.4%Reduced
Armistice Capital, LLC1,672,000$41.6M1.11%+136,000+8.9%Added
Tybourne Capital Management (HK) Ltd1,545,026$38.5M6.58%−105,294−6.4%Reduced
Morgan Stanley1,516,715$37.8M0.00%+487,490+47.4%Added
First Light Asset Management, LLC1,193,051$29.7M2.27%−357,420−23.1%Reduced
Westfield Capital Management Co LP1,038,917$25.9M0.14%+121,613+13.3%Added
Polar Capital Holdings Plc1,004,535$25.0M0.15%00.0%Unchanged
Suvretta Capital Management, LLC914,476$22.8M0.96%00.0%Unchanged
Candriam Luxembourg S.C.A.889,258$22.1M0.14%+20,000+2.3%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.883,105$22.0M0.06%+100,107+12.8%Added
Ra Capital Management, L.P.800,000$19.9M0.25%00.0%Unchanged
BlackRock Inc.575,030$14.3M0.00%+73,407+14.6%Added
AXA S.A.554,163$13.8M0.04%+770.0%Added
Parkman Healthcare Partners LLC524,253$13.1M1.60%+211,364+67.6%Added
Camber Capital Management LP450,000$11.2M0.39%00.0%Unchanged
Schonfeld Strategic Advisors LLC420,800$10.5M0.08%+313,800+293.3%Added
Price T Rowe Associates Inc401,646$10.0M0.00%+124,809+45.1%Added
Bank of America Corp396,812$9.88M0.00%−64,519−14.0%Reduced
Point72 Asset Management, L.P.342,594$8.53M0.02%+116,699+51.7%Added
Verition Fund Management LLC340,866$8.49M0.08%−399,673−54.0%Reduced
Platinum Investment Management Ltd333,001$8.29M0.33%−29,079−8.0%Reduced
Kennedy Capital Management, Inc.252,172$6.28M0.13%−164,313−39.5%Reduced
Rubric Capital Management LP205,423$5.12M0.15%00.0%Unchanged
Duquesne Family Office LLCSuperinvestorDuquesne Family Office190,200$4.74M0.13%+190,200New
Handelsbanken Fonder AB179,800$4.48M0.02%+40,000+28.6%Added
Renaissance Technologies LLC165,700$4.13M0.01%+60,200+57.1%Added
HighVista Strategies LLC158,293$3.94M1.41%00.0%Unchanged
Soleus Capital Management, L.P.153,000$3.81M0.33%+58,000+61.1%Added
Voya Investment Management LLC136,775$3.41M0.00%+23,625+20.9%Added
Legal & General Group Plc133,068$3.31M0.00%+263+0.2%Added
DAFNA Capital Management LLC122,200$3.04M0.69%00.0%Unchanged
Trexquant Investment LP92,552$2.30M0.05%−103,771−52.9%Reduced
UBS Oconnor LLC84,980$2.12M0.06%+11,379+15.5%Added
Pinnacle Associates Ltd80,090$1.99M0.03%+80,090New
Comerica Bank78,770$1.96M0.01%−3,080−3.8%Reduced
AlphaCentric Advisors LLC60,000$1.49M0.90%+60,000New
Citadel Advisors LLC59,440$1.48M0.00%−235,025−79.8%Reduced
Goldman Sachs Group Inc55,450$1.38M0.00%+55,450New
TD Asset Management Inc54,986$1.37M0.00%+19,800+56.3%Added
L & S Advisors Inc50,260$1.25M0.14%+40,070+393.2%Added
Two Sigma Advisers, LP46,600$1.16M0.00%−15,607−25.1%Reduced
National Bank of Canada48,700$1.11M0.00%+48,700New
Harbor Capital Advisors, Inc.43,480$1.08M0.14%+16,792+62.9%Added
Skandinaviska Enskilda Banken AB (publ)42,729$1.06M0.01%+42,729New
Wexford Capital LP34,879$868.5K0.18%00.0%Unchanged
Allianz Asset Management GmbH30,600$761.9K0.00%00.0%Unchanged
Two Sigma Investments, LP28,585$711.8K0.00%−75,043−72.4%Reduced
DekaBank Deutsche Girozentrale30,000$700.0K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The25,958$646.4K0.00%+12,785+97.1%Added
State Street Corp25,872$644.2K0.00%−3,694−12.5%Reduced
Woodstock Corp24,981$622.0K0.06%+3,502+16.3%Added
Concurrent Investment Advisors, LLC21,799$542.8K0.02%+21,799New
Geode Capital Management, LLC21,377$532.3K0.00%+2,540+13.5%Added
Gilder Gagnon Howe & Co LLC21,268$529.6K0.01%+21,268New
Jane Street Group, LLC20,197$502.9K0.00%−62,753−75.7%Reduced
Tocqueville Asset Management L.P.17,450$434.5K0.01%−5,900−25.3%Reduced
JPMorgan Chase & Co15,588$388.1K0.00%+5,482+54.2%Added
ADAR1 Capital Management, LLC14,430$359.3K0.10%−60,395−80.7%Reduced
Horizon Kinetics Asset Management LLC14,396$358.5K0.01%00.0%Unchanged
Erste Asset Management GmbH14,000$343.7K0.00%00.0%Unchanged
Danske Bank A/S13,330$331.9K0.00%+13,330New
Bellevue Group AG12,500$311.3K0.00%−7,500−37.5%Reduced
Exchange Traded Concepts, LLC12,421$309.3K0.01%+5,694+84.6%Added
Walleye Trading LLC11,371$283.1K0.00%−38,870−77.4%Reduced
UBS Group AG9,982$248.6K0.00%−1,168−10.5%Reduced
Simplex Trading, LLC9,830$244.0K0.01%+9,830New
Cubist Systematic Strategies, LLC9,420$234.6K0.00%−104,481−91.7%Reduced
Fishman Jay A Ltd9,000$224.1K0.02%−25,500−73.9%Reduced
PEAK6 Investments LLC9,000$224.1K0.01%00.0%Unchanged
BNP Paribas Arbitrage, SA8,834$220.0K0.00%−28,017−76.0%Reduced
PDS Planning, Inc8,450$210.4K0.02%+8,450New
Deutsche Bank AG8,070$200.9K0.00%−302−3.6%Reduced
The PNC Financial Services Group, Inc.7,700$191.7K0.00%+140+1.9%Added
China Universal Asset Management Co., Ltd.6,859$170.8K0.02%+2,858+71.4%Added
Virtus ETF Advisers LLC5,774$143.8K0.08%−398−6.4%Reduced
Leonteq Securities AG5,000$124.5K0.02%00.0%Unchanged
HighMark Wealth Management LLC4,435$110.4K0.07%00.0%Unchanged
Natixis2,568$63.2K0.00%−61−2.3%Reduced
First Manhattan Co2,200$54.8K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,389$34.6K0.00%−594−30.0%Reduced
GAMMA Investing LLC871$21.7K0.00%+349+66.9%Added
Rhumbline Advisers639$15.9K0.00%+229+55.9%Added
Tower Research Capital LLC (TRC)411$10.2K0.00%−1,917−82.3%Reduced
US Bancorp300$7.47K0.00%+300New
Royal Bank of Canada287$7.00K0.00%−59−17.1%Reduced
Citigroup Inc128$3.19K0.00%−15,500−99.2%Reduced
Macroview Investment Management LLC126$3.14K0.00%00.0%Unchanged
Daiwa Securities Group Inc.103$3.00K0.00%00.0%Unchanged
Group One Trading, L.P.91$2.27K0.00%−26,173−99.7%Reduced
Barclays PLC84$2.09K0.00%−14,948−99.4%Reduced
Gen-Wealth Partners Inc39$9710.00%+39New
Northwestern Mutual Wealth Management Co5$1250.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)4$1000.00%−454−99.1%Reduced
Jefferies Financial Group Inc.0$00.00%−1,948,000−100.0%Sold out
Ridgeback Capital Investments L.P.0$00.00%−844,235−100.0%Sold out
Nomura Holdings Inc0$00.00%−400,000−100.0%Sold out
FMR LLC0$00.00%−266,347−100.0%Sold out
Millennium Management LLC0$00.00%−249,135−100.0%Sold out