Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 99
- −11 vs. Q2 2025
- Shares held
- 36.9M
- −4.29M (−10.4%) vs. Q2 2025
- Total value
- $285.6M
- −$718.9K (−0.3%) vs. Q2 2025
- New holders
- 10
- 39 more added
- Sold out
- 21
- 23 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 10,885,357 | $84.3M | 0.61% | 00.0% | Unchanged |
| FCPM III Services B.V. | 3,452,330 | $26.7M | 5.34% | 00.0% | Unchanged |
| Armistice Capital, LLC | 2,978,000 | $23.0M | 0.72% | +178,000+6.4% | Added |
| Westfield Capital Management Co LP | 2,952,543 | $22.9M | 0.10% | +172,052+6.2% | Added |
| Siren, L.L.C. | 2,012,752 | $15.6M | 0.61% | 00.0% | Unchanged |
| Long Focus Capital Management, LLC | 1,418,695 | $11.0M | 0.63% | +101,402+7.7% | Added |
| Price T Rowe Associates Inc | 1,384,794 | $10.7M | 0.00% | −83,599−5.7% | Reduced |
| Acadian Asset Management LLC | 1,314,556 | $10.2M | 0.02% | +616,055+88.2% | Added |
| Candriam Luxembourg S.C.A. | 1,172,387 | $9.07M | 0.05% | 00.0% | Unchanged |
| Principal Financial Group Inc | 1,148,402 | $8.89M | 0.00% | +451,135+64.7% | Added |
| Millennium Management LLC | 1,054,746 | $8.16M | 0.01% | −388,873−26.9% | Reduced |
| Morgan Stanley | 822,705 | $6.37M | 0.00% | −214,448−20.7% | Reduced |
| Bank of America Corp | 591,535 | $4.58M | 0.00% | −239,099−28.8% | Reduced |
| Renaissance Technologies LLC | 518,700 | $4.01M | 0.01% | +200,300+62.9% | Added |
| Silvercrest Asset Management Group LLC | 476,976 | $3.69M | 0.02% | +211,283+79.5% | Added |
| Point72 Asset Management, L.P. | 430,900 | $3.34M | 0.01% | −1,341,700−75.7% | Reduced |
| Jefferies Financial Group Inc. | 401,926 | $3.11M | 0.03% | −59,174−12.8% | Reduced |
| BlackRock, Inc. | 282,418 | $2.19M | 0.00% | +18,070+6.8% | Added |
| Palo Alto Investors LP | 221,071 | $1.71M | 0.32% | −27,863−11.2% | Reduced |
| Legal & General Group Plc | 197,917 | $1.53M | 0.00% | +23,007+13.2% | Added |
| Pinnacle Associates Ltd | 196,618 | $1.52M | 0.02% | +24,665+14.3% | Added |
| Eversept Partners, LP | 194,440 | $1.50M | 0.12% | −17,029−8.1% | Reduced |
| Citadel Advisors LLC | 189,027 | $1.46M | 0.00% | +49,560+35.5% | Added |
| Platinum Investment Management Ltd | 184,603 | $1.43M | 0.09% | −100,778−35.3% | Reduced |
| Two Sigma Investments, LP | 184,537 | $1.43M | 0.00% | +128,339+228.4% | Added |
| TD Asset Management Inc | 178,092 | $1.38M | 0.00% | −15,000−7.8% | Reduced |
| Two Sigma Advisers, LP | 156,700 | $1.21M | 0.00% | +86,500+123.2% | Added |
| Birchview Capital, LP | 154,000 | $1.19M | 0.90% | +154,000 | New |
| Handelsbanken Fonder AB | 150,000 | $1.16M | 0.00% | −50,000−25.0% | Reduced |
| Manufacturers Life Insurance Company, The | 140,492 | $1.09M | 0.00% | 00.0% | Unchanged |
| Rangeley Capital, LLC | 130,000 | $1.01M | 0.95% | +55,000+73.3% | Added |
| Moore Capital Management, LP | 125,000 | $967.5K | 0.02% | +50,000+66.7% | Added |
| Cubist Systematic Strategies, LLC | 103,410 | $800.4K | 0.01% | +15,693+17.9% | Added |
| Jane Street Group, LLC | 102,459 | $793.0K | 0.00% | +79,852+353.2% | Added |
| Monimus Capital Management, LP | 85,224 | $659.6K | 0.49% | 00.0% | Unchanged |
| State Street Corp | 74,405 | $575.9K | 0.00% | +8,408+12.7% | Added |
| Nan Fung Group Holdings Ltd | 68,943 | $533.6K | 0.90% | 00.0% | Unchanged |
| DAFNA Capital Management LLC | 64,492 | $499.2K | 0.12% | 00.0% | Unchanged |
| SEI Investments Co | 49,056 | $379.7K | 0.00% | +38,419+361.2% | Added |
| State of Tennessee, Treasury Department | 44,842 | $347.1K | 0.00% | +30,460+211.8% | Added |
| Harbor Capital Advisors, Inc. | 41,368 | $320.0K | 0.02% | −97,293−70.2% | Reduced |
| Man Group plc | 40,891 | $316.5K | 0.00% | +12,216+42.6% | Added |
| Geode Capital Management, LLC | 39,925 | $309.0K | 0.00% | −487−1.2% | Reduced |
| DekaBank Deutsche Girozentrale | 30,000 | $220.0K | 0.00% | 00.0% | Unchanged |
| Dynamic Technology Lab Private Ltd | 27,959 | $216.0K | 0.04% | −17,991−39.2% | Reduced |
| Quadrature Capital Ltd | 27,894 | $215.6K | 0.00% | +10,156+57.3% | Added |
| Susquehanna International Group, LLP | 26,629 | $206.1K | 0.00% | +62+0.2% | Added |
| Alps Advisors Inc | 24,123 | $186.7K | 0.00% | −1,634−6.3% | Reduced |
| Woodstock Corp | 23,927 | $185.2K | 0.02% | 00.0% | Unchanged |
| Jump Financial, LLC | 21,421 | $165.8K | 0.00% | +4,681+28.0% | Added |
| State of New Jersey Common Pension Fund D | 20,105 | $155.6K | 0.00% | +20,105 | New |
| Portland Investment Counsel Inc. | 15,000 | $116.1K | 0.03% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 14,972 | $115.9K | 0.00% | +2,668+21.7% | Added |
| Horizon Kinetics Asset Management LLC | 14,396 | $111.4K | 0.00% | +604+4.4% | Added |
| Cerity Partners LLC | 14,350 | $111.1K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 14,302 | $110.7K | 0.00% | +4,699+48.9% | Added |
| Erste Asset Management GmbH | 14,000 | $106.5K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 13,421 | $103.9K | 0.00% | −1,981−12.9% | Reduced |
| Squarepoint Ops LLC | 13,259 | $102.6K | 0.00% | +1,385+11.7% | Added |
| Virtus Investment Advisers, Inc. | 13,094 | $101.3K | 0.03% | +2,273+21.0% | Added |
| The PNC Financial Services Group, Inc. | 13,080 | $101.2K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 12,953 | $100.3K | 0.00% | +12,953 | New |
| Royal Bank of Canada | 12,733 | $99.0K | 0.00% | +2,371+22.9% | Added |
| Graham Capital Management, L.P. | 12,375 | $95.8K | 0.00% | −727−5.5% | Reduced |
| Tocqueville Asset Management L.P. | 12,300 | $95.2K | 0.00% | −10,600−46.3% | Reduced |
| XTX Topco Ltd | 11,648 | $90.2K | 0.00% | +11,648 | New |
| Crossmark Global Holdings, Inc. | 11,390 | $88.2K | 0.00% | +10.0% | Added |
| UBS Group AG | 11,373 | $88.0K | 0.00% | −22,002−65.9% | Reduced |
| FNY Investment Advisers, LLC | 10,500 | $81.0K | 0.03% | +10,500 | New |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 10,116 | $78.3K | 0.00% | +10,116 | New |
| JPMorgan Chase & Co | 8,127 | $62.9K | 0.00% | +490+6.4% | Added |
| China Universal Asset Management Co., Ltd. | 8,104 | $62.7K | 0.01% | −762−8.6% | Reduced |
| Assetmark, Inc | 3,625 | $28.1K | 0.00% | +1,552+74.9% | Added |
| Rhumbline Advisers | 3,275 | $25.3K | 0.00% | +270+9.0% | Added |
| Citigroup Inc | 2,601 | $20.1K | 0.00% | +1,688+184.9% | Added |
| Barclays PLC | 2,272 | $17.6K | 0.00% | −1,204−34.6% | Reduced |
| GAMMA Investing LLC | 2,116 | $16.4K | 0.00% | +628+42.2% | Added |
| Natixis | 1,947 | $14.6K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 1,787 | $13.8K | 0.00% | +82+4.8% | Added |
| Tower Research Capital LLC (TRC) | 1,665 | $12.9K | 0.00% | −2,494−60.0% | Reduced |
| Clearstead Advisors, LLC | 1,393 | $10.8K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 995 | $7.70K | 0.00% | −131−11.6% | Reduced |
| BNP Paribas Arbitrage, SA | 811 | $6.28K | 0.00% | +281+53.0% | Added |
| Walleye Trading LLC | 630 | $4.88K | 0.00% | +630 | New |
| Manchester Capital Management LLC | 590 | $4.57K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 435 | $3.37K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 316 | $2.45K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 250 | $1.85K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 200 | $1.55K | 0.00% | 00.0% | Unchanged |
| Winch Advisory Services, LLC | 172 | $1.33K | 0.00% | 00.0% | Unchanged |
| Toth Financial Advisory Corp | 150 | $1.16K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 103 | $1.00K | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 18 | $139 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 18 | $132 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 11 | $85 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 7 | $54 | 0.00% | +1+16.7% | Added |
| EverSource Wealth Advisors, LLC | 6 | $46 | 0.00% | +6 | New |
| Rockefeller Capital Management L.P. | 5 | $39 | 0.00% | +5 | New |
| Caitlin John, LLC | 2 | $15 | 0.00% | +2 | New |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −1,203,244−100.0% | Sold out |