Bicycle Therapeutics PLC
BCYC- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001761612
In the last 90 days, Bicycle Therapeutics PLC insiders filed 0 open-market purchases and 5 sales; 103 institutions reported holding it in 13F filings for Q2 2026, worth $157.9M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Bicycle Therapeutics PLC as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 99
- −11 vs. Q2 2025
- Shares held
- 36.9M
- −4.29M (−10.4%) vs. Q2 2025
- Total value
- $285.6M
- −$718.9K (−0.3%) vs. Q2 2025
- New holders
- 10
- 39 more added
- Sold out
- 21
- 23 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting BCYC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 103 | $157.9M |
| Q1 2026 | 98 | $173.6M |
| Q4 2025 | 109 | $276.9M |
| Q3 2025 | 99 | $285.6M |
| Q2 2025 | 110 | $286.3M |
| Q1 2025 | 95 | $354.4M |
| Q4 2024 | 97 | $586.5M |
| Q3 2024 | 105 | $915.3M |
| Q2 2024 | 107 | $804.0M |
| Q1 2024 | 95 | $759.1M |
| Q4 2023 | 101 | $567.4M |
| Q3 2023 | 101 | $651.3M |
| Q2 2023 | 85 | $618.5M |
| Q1 2023 | 89 | $498.9M |
| Q4 2022 | 87 | $695.9M |
| Q3 2022 | 79 | $538.0M |
| Q2 2022 | 82 | $381.1M |
| Q1 2022 | 105 | $884.5M |
| Q4 2021 | 101 | $1.31B |
| Q3 2021 | 69 | $591.1M |
| Q2 2021 | 54 | $376.9M |
| Q1 2021 | 39 | $341.2M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Bicycle Therapeutics PLC; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Caitlin John, LLC | 2 | $15 | 0.00% | +2 | New |
| Rockefeller Capital Management L.P. | 5 | $39 | 0.00% | +5 | New |
| EverSource Wealth Advisors, LLC | 6 | $46 | 0.00% | +6 | New |
| SBI Securities Co., Ltd. | 7 | $54 | 0.00% | +1+16.7% | Added |
| Ronald Blue Trust, Inc. | 11 | $85 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 18 | $132 | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 18 | $139 | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 103 | $1.00K | 0.00% | 00.0% | Unchanged |
| Toth Financial Advisory Corp | 150 | $1.16K | 0.00% | 00.0% | Unchanged |
| Winch Advisory Services, LLC | 172 | $1.33K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 200 | $1.55K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 250 | $1.85K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 316 | $2.45K | 0.00% | 00.0% | Unchanged |
| HighMark Wealth Management LLC | 435 | $3.37K | 0.00% | 00.0% | Unchanged |
| Manchester Capital Management LLC | 590 | $4.57K | 0.00% | 00.0% | Unchanged |
| Walleye Trading LLC | 630 | $4.88K | 0.00% | +630 | New |
| BNP Paribas Arbitrage, SA | 811 | $6.28K | 0.00% | +281+53.0% | Added |
| GF Fund Management Co. Ltd. | 995 | $7.70K | 0.00% | −131−11.6% | Reduced |
| Clearstead Advisors, LLC | 1,393 | $10.8K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,665 | $12.9K | 0.00% | −2,494−60.0% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,787 | $13.8K | 0.00% | +82+4.8% | Added |
| Natixis | 1,947 | $14.6K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 2,116 | $16.4K | 0.00% | +628+42.2% | Added |
| Barclays PLC | 2,272 | $17.6K | 0.00% | −1,204−34.6% | Reduced |
| Citigroup Inc | 2,601 | $20.1K | 0.00% | +1,688+184.9% | Added |
| Rhumbline Advisers | 3,275 | $25.3K | 0.00% | +270+9.0% | Added |
| Assetmark, Inc | 3,625 | $28.1K | 0.00% | +1,552+74.9% | Added |
| China Universal Asset Management Co., Ltd. | 8,104 | $62.7K | 0.01% | −762−8.6% | Reduced |
| JPMorgan Chase & Co | 8,127 | $62.9K | 0.00% | +490+6.4% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 10,116 | $78.3K | 0.00% | +10,116 | New |
| FNY Investment Advisers, LLC | 10,500 | $81.0K | 0.03% | +10,500 | New |
| UBS Group AG | 11,373 | $88.0K | 0.00% | −22,002−65.9% | Reduced |
| Crossmark Global Holdings, Inc. | 11,390 | $88.2K | 0.00% | +10.0% | Added |
| XTX Topco Ltd | 11,648 | $90.2K | 0.00% | +11,648 | New |
| Tocqueville Asset Management L.P. | 12,300 | $95.2K | 0.00% | −10,600−46.3% | Reduced |
| Graham Capital Management, L.P. | 12,375 | $95.8K | 0.00% | −727−5.5% | Reduced |
| Royal Bank of Canada | 12,733 | $99.0K | 0.00% | +2,371+22.9% | Added |
| JustInvest LLC | 12,953 | $100.3K | 0.00% | +12,953 | New |
| The PNC Financial Services Group, Inc. | 13,080 | $101.2K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 13,094 | $101.3K | 0.03% | +2,273+21.0% | Added |
| Squarepoint Ops LLC | 13,259 | $102.6K | 0.00% | +1,385+11.7% | Added |
| Engineers Gate Manager LP | 13,421 | $103.9K | 0.00% | −1,981−12.9% | Reduced |
| Erste Asset Management GmbH | 14,000 | $106.5K | 0.00% | 00.0% | Unchanged |
| Federation des caisses Desjardins du Quebec | 14,302 | $110.7K | 0.00% | +4,699+48.9% | Added |
| Cerity Partners LLC | 14,350 | $111.1K | 0.00% | 00.0% | Unchanged |
| Horizon Kinetics Asset Management LLC | 14,396 | $111.4K | 0.00% | +604+4.4% | Added |
| Ameriprise Financial Inc | 14,972 | $115.9K | 0.00% | +2,668+21.7% | Added |
| Portland Investment Counsel Inc. | 15,000 | $116.1K | 0.03% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 20,105 | $155.6K | 0.00% | +20,105 | New |
| Jump Financial, LLC | 21,421 | $165.8K | 0.00% | +4,681+28.0% | Added |
| Woodstock Corp | 23,927 | $185.2K | 0.02% | 00.0% | Unchanged |
| Alps Advisors Inc | 24,123 | $186.7K | 0.00% | −1,634−6.3% | Reduced |
| Susquehanna International Group, LLP | 26,629 | $206.1K | 0.00% | +62+0.2% | Added |
| Quadrature Capital Ltd | 27,894 | $215.6K | 0.00% | +10,156+57.3% | Added |
| Dynamic Technology Lab Private Ltd | 27,959 | $216.0K | 0.04% | −17,991−39.2% | Reduced |
| DekaBank Deutsche Girozentrale | 30,000 | $220.0K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 39,925 | $309.0K | 0.00% | −487−1.2% | Reduced |
| Man Group plc | 40,891 | $316.5K | 0.00% | +12,216+42.6% | Added |
| Harbor Capital Advisors, Inc. | 41,368 | $320.0K | 0.02% | −97,293−70.2% | Reduced |
| State of Tennessee, Treasury Department | 44,842 | $347.1K | 0.00% | +30,460+211.8% | Added |
| SEI Investments Co | 49,056 | $379.7K | 0.00% | +38,419+361.2% | Added |
| DAFNA Capital Management LLC | 64,492 | $499.2K | 0.12% | 00.0% | Unchanged |
| Nan Fung Group Holdings Ltd | 68,943 | $533.6K | 0.90% | 00.0% | Unchanged |
| State Street Corp | 74,405 | $575.9K | 0.00% | +8,408+12.7% | Added |
| Monimus Capital Management, LP | 85,224 | $659.6K | 0.49% | 00.0% | Unchanged |
| Jane Street Group, LLC | 102,459 | $793.0K | 0.00% | +79,852+353.2% | Added |
| Cubist Systematic Strategies, LLC | 103,410 | $800.4K | 0.01% | +15,693+17.9% | Added |
| Moore Capital Management, LP | 125,000 | $967.5K | 0.02% | +50,000+66.7% | Added |
| Rangeley Capital, LLC | 130,000 | $1.01M | 0.95% | +55,000+73.3% | Added |
| Manufacturers Life Insurance Company, The | 140,492 | $1.09M | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 150,000 | $1.16M | 0.00% | −50,000−25.0% | Reduced |
| Birchview Capital, LP | 154,000 | $1.19M | 0.90% | +154,000 | New |
| Two Sigma Advisers, LP | 156,700 | $1.21M | 0.00% | +86,500+123.2% | Added |
| TD Asset Management Inc | 178,092 | $1.38M | 0.00% | −15,000−7.8% | Reduced |
| Two Sigma Investments, LP | 184,537 | $1.43M | 0.00% | +128,339+228.4% | Added |
| Platinum Investment Management Ltd | 184,603 | $1.43M | 0.09% | −100,778−35.3% | Reduced |
| Citadel Advisors LLC | 189,027 | $1.46M | 0.00% | +49,560+35.5% | Added |
| Eversept Partners, LP | 194,440 | $1.50M | 0.12% | −17,029−8.1% | Reduced |
| Pinnacle Associates Ltd | 196,618 | $1.52M | 0.02% | +24,665+14.3% | Added |
| Legal & General Group Plc | 197,917 | $1.53M | 0.00% | +23,007+13.2% | Added |
| Palo Alto Investors LP | 221,071 | $1.71M | 0.32% | −27,863−11.2% | Reduced |
| BlackRock, Inc. | 282,418 | $2.19M | 0.00% | +18,070+6.8% | Added |
| Jefferies Financial Group Inc. | 401,926 | $3.11M | 0.03% | −59,174−12.8% | Reduced |
| Point72 Asset Management, L.P. | 430,900 | $3.34M | 0.01% | −1,341,700−75.7% | Reduced |
| Silvercrest Asset Management Group LLC | 476,976 | $3.69M | 0.02% | +211,283+79.5% | Added |
| Renaissance Technologies LLC | 518,700 | $4.01M | 0.01% | +200,300+62.9% | Added |
| Bank of America Corp | 591,535 | $4.58M | 0.00% | −239,099−28.8% | Reduced |
| Morgan Stanley | 822,705 | $6.37M | 0.00% | −214,448−20.7% | Reduced |
| Millennium Management LLC | 1,054,746 | $8.16M | 0.01% | −388,873−26.9% | Reduced |
| Principal Financial Group Inc | 1,148,402 | $8.89M | 0.00% | +451,135+64.7% | Added |
| Candriam Luxembourg S.C.A. | 1,172,387 | $9.07M | 0.05% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 1,314,556 | $10.2M | 0.02% | +616,055+88.2% | Added |
| Price T Rowe Associates Inc | 1,384,794 | $10.7M | 0.00% | −83,599−5.7% | Reduced |
| Long Focus Capital Management, LLC | 1,418,695 | $11.0M | 0.63% | +101,402+7.7% | Added |
| Siren, L.L.C. | 2,012,752 | $15.6M | 0.61% | 00.0% | Unchanged |
| Westfield Capital Management Co LP | 2,952,543 | $22.9M | 0.10% | +172,052+6.2% | Added |
| Armistice Capital, LLC | 2,978,000 | $23.0M | 0.72% | +178,000+6.4% | Added |
| FCPM III Services B.V. | 3,452,330 | $26.7M | 5.34% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 10,885,357 | $84.3M | 0.61% | 00.0% | Unchanged |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −1,203,244−100.0% | Sold out |